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生物物理学杂志2007年第10期封面 购买


hepatocyte growth factor receptor c-met is associated with fas and when activated enhances drug-induced apoptosis in pediatric b acute lymphoblastic leukemia with t..
retinoic acid inhibits -catenin through suppression of cox-
mapping the interacting domains of stim1 and orai1 in ca2+ release-activated ca2+ channel activation
photosynthetic antenna size in higher plants is controlled by the plastoquinone redox state at the post-transcriptional rather than transcriptional level
glutathione depletion down-regulates tumor necrosis factor -induced nf-b activity via ib kinase-dependent and -independent mechanisms
toc159- and toc75-independent import of a transit sequence-less precursor into the inner envelope of chloroplasts
regulation of human cytidine triphosphate synthetase 1 by glycogen synthase kinase 3
a role for myosin 1e in cortical granule exocytosis in xenopus oocytes
exploring the ubiquinone binding cavity of respiratory complex i
enzymatic characterization of dihydrolipoamide dehydrogenase from streptococcus pneumoniae harboring its own substrate
phosphorylation blocks the activity of tubulin polymerization-promoting protein (tppp)
topology inversion of secg is essential for cytosolic seca-dependent stimulation of protein translocation
ubiquitination of -arrestin links seven-transmembrane receptor endocytosis and erk activation
design of a specific activator for skeletal muscle sodium channels uncovers channel architecture
human t-cell leukemia virus type 1 tax oncoprotein prevents dna damage-induced chromatin egress of hyperphosphorylated chk2
ibogaine, a noncompetitive inhibitor of serotonin transport, acts by stabilizing the cytoplasm-facing state of the transporter
blockade of tumor necrosis factor-induced bid cleavage by caspase-resistant rb
cytoskeletal anchoring of glast determines susceptibility to brain damage
translation-coupled translocation of yeast fumarase into mitochondria in vivo
a novel cav1.2 n terminus expressed in smooth muscle cells of resistance size arteries modifies channel regulation by auxiliary subunits
comparative biophysical characterization of p53 with the pro-apoptotic bak and the anti-apoptotic bcl-xl
gq directly activates p63rhogef and trio via a conserved extension of the dbl homology-associated pleckstrin homology domain
the neurodegenerative disease protein ataxin-1 antagonizes the neuronal survival function of myocyte enhancer factor-2
changes in g protein-coupled receptor sorting protein affinity regulate postendocytic targeting of g protein-coupled receptors
characterization of the c-terminal domain of a potassium channel from streptomyces lividans (kcsa)
activation of the diguanylate cyclase pled by phosphorylation-mediated dimerization
tap73 is a downstream target of p53 in controlling the cellular defense against stress
the metabolism and dechlorination of chlorotyrosine in vivo
src family kinases promote vessel stability by antagonizing the rho/rock pathway
gabaa 6-containing receptors are selectively compromised in cerebellar granule cells of the ataxic mouse, stargazer
the membrane topology of rtn3 and its effect on binding of rtn3 to bace1
contributions of galectin-3 and -9 to epithelial cell adhesion analyzed by single cell force spectroscopy
pro-apoptotic bim induction in response to nerve growth factor deprivation requires simultaneous activation of three different death signaling pathways
cytokine-like 1 (cytl1) regulates the chondrogenesis of mesenchymal cells
binding of cbl to a phospholipase c1-docking site on platelet-derived growth factor receptor provides a dual mechanism of negative regulation
cellular turnover of the polyglutamine disease protein ataxin-3 is regulated by its catalytic activity
an asparaginyl endopeptidase mediates in vivo protein backbone cyclization
kinase-active interleukin-1 receptor-associated kinases promote polyubiquitination and degradation of the pellino family
alternatively spliced t-cell receptor transcripts are up-regulated in response to disruption of either splicing elements or reading frame
activation of the integrated stress response regulates lovastatin-induced apoptosis
mechanism of stabilization of a bacterial collagen triple helix in the absence of hydroxyproline
cytochrome b5 increases the rate of product formation by cytochrome p450 2b4 and competes with cytochrome p450 reductase for a binding site on cytochrome p450 2b4
direct protein kinase c-dependent phosphorylation regulates the cell surface stability and activity of the potassium chloride cotransporter kcc2
the active protein-conducting channel of escherichia coli contains an apolar patch
analysis of carboxysomes from synechococcus pcc7942 reveals multiple rubisco complexes with carboxysomal proteins ccmm and ccaa
disruption of telomere maintenance by depletion of the mre11/rad50/nbs1 complex in cells that use alternative lengthening of telomeres
raft-dependent endocytosis of autocrine motility factor is phosphatidylinositol 3-kinase-dependent in breast carcinoma cells
glutathione binding to the bcl-2 homology-3 domain groove
stabilization of p53 in human cytomegalovirus-initiated cells is associated with sequestration of hdm2 and decreased p53 ubiquitination
the transforming acidic coiled coil 3 protein is essential for spindle-dependent chromosome alignment and mitotic survival
nucleobindin 1 controls the unfolded protein response by inhibiting atf6 activation
selective cysteine protease inhibition contributes to blood-feeding success of the tick ixodes scapularis
identification of residues important for agonist recognition and activation in gpr40
structure of compstatin in complex with complement component c3c reveals a new mechanism of complement inhibition
sorafenib functions to potently suppress ret tyrosine kinase activity by direct enzymatic inhibition and promoting ret lysosomal degradation independent of proteaso..
the ut-a1 urea transporter interacts with snapin, a snare-associated protein
the energy sensor amp-activated protein kinase directly regulates the mammalian foxo3 transcription factor
purification, cloning, and expression of an /-galactoside -2,3-sialyltransferase from a luminous marine bacterium, photobacterium phosphoreum
characterization of the metabolic activation of hepatitis c virus nucleoside inhibitor -d-2‘-deoxy-2‘-fluoro-2‘-c-methylcytidine (psi-6130) and identification of..
1,25-dihydroxyvitamin d3 suppresses renin gene transcription by blocking the activity of the cyclic amp response element in the renin gene promoter
mcl-1 as a buffer for proapoptotic bcl-2 family members during trail-induced apoptosis
differential regulation of vitamin d receptor (vdr) by the p53 family
caveolin-1 regulates the delivery and endocytosis of the glutamate transporter, excitatory amino acid carrier 1
akt mediates the effect of insulin on epithelial sodium channels by inhibiting nedd4-2
identification of a redox-sensitive cysteine in gcp60 that regulates its interaction with golgin-160
ccaat/enhancer-binding protein (c/ebp) maintains amelogenin expression in the absence of c/ebp in vivo
regulation of e2f1 function by the nuclear corepressor kap1
identification of novel autoxidation products of the -3 fatty acid eicosapentaenoic acid in vitro and in vivo
regulation of human lung adenocarcinoma cell migration and invasion by macrophage migration inhibitory factor
the pp2a-associated protein 4 plays a critical role in the regulation of cell spreading and migration
regulation of mesodermal differentiation of mouse embryonic stem cells by basement membranes
investigation into the role of macrophages in the formation and degradation of 2-microglobulin amyloid fibrils
visualization and manipulation of plasma membrane-endoplasmic reticulum contact sites indicates the presence of additional molecular components within the stim1-ora..
development of a stabilized form of the regulatory ck2 subunit that inhibits cell proliferation
evolutionarily conserved mammalian adenine nucleotide translocase 4 is essential for spermatogenesis
hepatocyte growth factor-regulated tyrosine kinase substrate (hrs) mediates post-endocytic trafficking of protease-activated receptor 2 and calcitonin receptor-like..
hierarchical delivery of an essential host colonization factor in enteropathogenic escherichia coli
diffusion and not active transport underlies and limits erk1/2 synapse-to-nucleus signaling in hippocampal neurons
snapin, a new regulator of receptor signaling, augments 1a-adrenoceptor-operated calcium influx through trpc6
genetic and pharmacological inhibition of rho-associated kinase ii enhances adipogenesis
phosphoinositide 3-kinase-independent non-genomic signals transit from the androgen receptor to akt1 in membrane raft microdomains
corticosteroid-binding globulin, a structural basis for steroid transport and proteinase-triggered release
crucial role of the disulfide bridge between botulinum neurotoxin light and heavy chains in protease translocation across membranes
rab-gtpase-dependent endocytic recycling of kv1.5 in atrial myocytes
enzymes responsible for synthesis of corneal keratan sulfate glycosaminoglycans
n-terminal extension of n-methylpurine dna glycosylase is required for turnover in hypoxanthine excision reaction
p24a, a type i transmembrane protein, controls arf1-dependent resensitization of protease-activated receptor-2 by influence on receptor trafficking
functional consequence of protein kinase a-dependent phosphorylation of the cardiac ryanodine receptor
iqgap1 regulates salmonella invasion through interactions with actin, rac1, and cdc42
characterization of a mutation in the phox homology domain of the nadph oxidase component p40phox identifies a mechanism for negative regulation of superoxide produ..
the ras-dependent erf control of cell proliferation and differentiation is mediated by c-myc repression
stress hormones regulate interleukin-6 expression by human ovarian carcinoma cells through a src-dependent mechanism
a ferritin-responsive internal ribosome entry site regulates folate metabolism
substrate modification with lysine 63-linked ubiquitin chains through the ubc13-uev1a ubiquitin-conjugating enzyme
adipose tissue integrity as a prerequisite for systemic energy balance
mechanistic roles of leptin in osteogenic stimulation in thoracic ligament flavum cells
membrane translocation of p-rex1 is mediated by g protein subunits and phosphoinositide 3-kinase
live cell imaging of outward and inward vesiculation induced by the complement c5b-9 complex
p21waf1/cip1 is a common transcriptional target of retinoid receptors
annexin 1 cleavage in activated neutrophils
regulation of heterotypic claudin compatibility
skeletal muscle fiber-type switching, exercise intolerance, and myopathy in pgc-1 muscle-specific knock-out animals
cross-sequence transmission of sporadic creutzfeldt-jakob disease creates a new prion strain
identification and characterization of human cdc7 nuclear retention and export sequences in the context of chromatin binding
t-cell intracellular antigen-1 (tia-1)-induced translational silencing promotes the decay of selected mrnas
allosteric transinhibition by specific antagonists in ccr2/cxcr4 heterodimers
characterization of ehp, a secreted complement inhibitory protein from staphylococcus aureus
synergy between the re-1 silencer of transcription and nfb in the repression of the neurotransmitter gene tac1 in human mesenchymal stem cells
the diaphanous inhibitory domain/diaphanous autoregulatory domain interaction is able to mediate heterodimerization between mdia1 and mdia2
matrix gla protein, an inhibitory morphogen in pulmonary vascular development
epigallocatechin-3-gallate (egcg), a green tea polyphenol, suppresses hepatic gluconeogenesis through 5‘-amp-activated protein kinase
proteolytic cleavage of ataxin-7 by caspase-7 modulates cellular toxicity and transcriptional dysregulation
ptx3 interacts with inter--trypsin inhibitor
connexin levels regulate keratinocyte differentiation in the epidermis
n-lysine propionylation controls the activity of propionyl-coa synthetase
predominant interaction of both ikaros and helios with the nurd complex in immature thymocytes
carboxyl-terminal proteolytic processing of cux1 by a caspase enables transcriptional activation in proliferating cells
development of cytosolic hypoxia and hypoxia-inducible factor stabilization are facilitated by aquaporin-1 expression
a structural hypothesis for the transition between bent and extended conformations of the leukocyte 2 integrins
structural basis of substrate-binding specificity of human arylamine n-acetyltransferases
nmr structural analysis of cadmium sensing by winged helix repressor cmtr
the chaotrope-soluble glycoprotein gp2 is a precursor of the insoluble glycoprotein framework of the chlamydomonas cell wall
glycogen synthase kinase-3 induces neuronal cell death via direct phosphorylation of mixed lineage kinase 3
zebrafish acid-sensing ion channel (asic) 4, characterization of homo- and heteromeric channels, and identification of regions important for activation by h+
unexpected inhibition of peptidoglycan ld-transpeptidase from enterococcus faecium by the -lactam imipenem
basal activation of p70s6k results in adipose-specific insulin resistance in protein-tyrosine phosphatase 1b–/– mice
mekk4 stimulation of p38 and jnk activity is negatively regulated by gsk3
stimulation of actin polymerization by vacuoles via cdc42p-dependent signaling
glutathione depletion is necessary for apoptosis in lymphoid cells independent of reactive oxygen species formation
cobalt stress in escherichia coli
ligand binding rapidly induces disulfide-dependent dimerization of glycoprotein vi on the platelet plasma membrane
janus kinase 3 regulates interleukin 2-induced mucosal wound repair through tyrosine phosphorylation of villin
polysialylated neuropilin-2 is expressed on the surface of human dendritic cells and modulates dendritic cell-t lymphocyte interactions
transmembrane segment iv contributes a functionally important interface for oligomerization of the class ii g protein-coupled secretin receptor
atr pathway is the primary pathway for activating g2/m checkpoint induction after re-replication
pgap1 knock-out mice show otocephaly and male infertility
cd44 regulates hepatocyte growth factor-mediated vascular integrity
nos2 regulation of nf-b by s-nitrosylation of p65
mutations designed to destabilize the receptor-bound conformation increase mica-nkg2d association rate and affinity
down syndrome critical region-1 is a transcriptional target of nuclear factor of activated t cells-c1 within the endocardium during heart development
peptide-receptive major histocompatibility complex class i molecules cycle between endoplasmic reticulum and cis-golgi in wild-type lymphocytes
structure/function characterization of µ-conotoxin kiiia, an analgesic, nearly irreversible blocker of mammalian neuronal sodium channels
lactogens promote beta cell survival through jak2/stat5 activation and bcl-xl upregulation
translocation of a phycoerythrin subunit across five biological membranes
dna binding suppresses human aif-m2 activity and provides a connection between redox chemistry, reactive oxygen species, and apoptosis
intrinsic signaling functions of the 4 integrin intracellular domain
stability of checkpoint kinase 2 is regulated via phosphorylation at serine 456
structure-function analysis of the wip role in t cell receptor-stimulated nfat activation
evidence for a dinuclear active site in the metallo--lactamase bcii with substoichiometric co(ii)
feasibility of pathways for transfer of acyl groups from mitochondria to the cytosol to form short chain acyl-coas in the pancreatic beta cell
conserved glutamate residues are critically involved in na+/nucleoside cotransport by human concentrative nucleoside transporter 1 (hcnt1)
the transmembrane domain is sufficient for sbh1p function, its association with the sec61 complex, and interaction with rtn1p
characterization of interactions of adapter protein rapl/nore1b with rap gtpases and their role in t cell migration
phenylalanine biosynthesis in arabidopsis thaliana
akt phosphorylates msti and prevents its proteolytic activation, blocking foxo3 phosphorylation and nuclear translocation
slc1 and slc4 encode partially redundant acyl-coenzyme a 1-acylglycerol-3-phosphate o-acyltransferases of budding yeast
ammonium scanning in an enzyme active site
binding between the integrin x2 (cd11c/cd18) and heparin
tm14 is a new member of the fibulin family (fibulin-7) that interacts with extracellular matrix molecules and is active for cell binding
klotho-related protein is a novel cytosolic neutral -glycosylceramidase
pre-steady-state kinetic characterization of the ap endonuclease activity of human ap endonuclease 1
tamoxifen induction of ccaat enhancer-binding protein is required for tamoxifen-induced apoptosis
reinvestigation of a selenopeptide with purportedly high glutathione peroxidase activity
increase in expression levels and resistance to sulfhydryl oxidation of peroxiredoxin isoforms in amyloid -resistant nerve cells
regulated proteolytic processing of tie1 modulates ligand responsiveness of the receptor-tyrosine kinase tie2
y box-binding protein-1 binds to the dengue virus 3‘-untranslated region and mediates antiviral effects
nerve growth factor induces endothelial cell invasion and cord formation by promoting matrix metalloproteinase-2 expression through the phosphatidylinositol 3-kinas..
dp5/hrk is a c-jun target gene and required for apoptosis induced by potassium deprivation in cerebellar granule neurons
regulation of ephexin1, a guanine nucleotide exchange factor of rho family gtpases, by fibroblast growth factor receptor-mediated tyrosine phosphorylation
a dimeric smac/diablo peptide directly relieves caspase-3 inhibition by xiap
interacting proteins dictate function of the minimal start domain phosphatidylcholine transfer protein/stard2
pseudomonas syringae type iii effector avrptob is phosphorylated in plant cells on serine 258, promoting its virulence activity
the m18 aspartyl aminopeptidase of the human malaria parasite plasmodium falciparum
the farnesyl-diphosphate/geranylgeranyl-diphosphate synthase of toxoplasma gondii is a bifunctional enzyme and a molecular target of bisphosphonates
disruption of cxc motif chemokine ligand-14 in mice ameliorates obesity-induced insulin resistance
role of adam-9 disintegrin-cysteine-rich domains in human keratinocyte migration
single molecule imaging of tid1/rdh54, a rad54 homolog that translocates on duplex dna and can disrupt joint molecules
purification, sequencing, and molecular identification of a mammalian pp-insp5 kinase that is activated when cells are exposed to hyperosmotic stress
cloning and characterization of two human vip1-like inositol hexakisphosphate and diphosphoinositol pentakisphosphate kinases
myoferlin regulates vascular endothelial growth factor receptor-2 stability and function
the structure of the haemophilus influenzae hmw1 pro-piece reveals a structural domain essential for bacterial two-partner secretion
nitro-fatty acid reaction with glutathione and cysteine
structural insight into the dual ligand specificity and mode of high density lipoprotein association of apolipoprotein d
ing1 mediates p53 accumulation and chromatin modification in response to oncogenic stress
heterodimerization with jun family members regulates c-fos nucleocytoplasmic traffic
high glucose increases angiopoietin-2 transcription in microvascular endothelial cells through methylglyoxal modification of msin3a
stereospecific proton transfer by a mobile catalyst in mammalian fructose-1,6-bisphosphate aldolase
the long form of the leptin receptor regulates stat5 and ribosomal protein s6 via alternate mechanisms
a single amino acid mutation in zebrafish (danio rerio) liver bile acid-binding protein can change the stoichiometry of ligand binding
the site of action of the antiterminator protein n from the lambdoid phage h-19b
jak2 tyrosine kinase phosphorylates pak1 and regulates pak1 activity and functions
leucine carboxyl methyltransferase-1 is necessary for normal progression through mitosis in mammalian cells
knockdown of the intraflagellar transport protein ift46 stimulates selective gene expression in mouse chondrocytes and affects early development in zebrafish
structural insights into activation of phosphatidylinositol 4-kinase (pik1) by yeast frequenin (frq1)
the mit domain of ubpy constitutes a chmp binding and endosomal localization signal required for efficient epidermal growth factor receptor degradation
noncanonical wnt-4 signaling enhances bone regeneration of mesenchymal stem cells in craniofacial defects through activation of p38 mapk
the bacteroides nbu1 integrase performs a homology-independent strand exchange to form a holliday junction intermediate
protection against -amyloid-induced apoptosis by peptides interacting with -amyloid
towards covalent vaccination
structural characterization of the human androgen receptor ligand-binding domain complexed with em5744, a rationally designed steroidal ligand bearing a bulky chain..
t-cell ubiquitin ligand affects cell death through a functional interaction with apoptosis-inducing factor, a key factor of caspase-independent apoptosis
cytosolic accumulation of hsp60 during apoptosis with or without apparent mitochondrial release
properties, regulation, and in vivo functions of a novel protein kinase d
ubiquitination of mammalian pex5p, the peroxisomal import receptor
induction of endogenous uncoupling protein 3 suppresses mitochondrial oxidant emission during fatty acid-supported respiration
respiratory deficiency mediates the regulation of cho1-encoded phosphatidylserine synthase by mrna stability in saccharomyces cerevisiae
incorporation of newly synthesized fatty acids into cytosolic glycerolipids in pea leaves occurs via acyl editing
microbial products stimulate human toll-like receptor 2 expression through histone modification surrounding a proximal nf-b-binding site
a pathway separate from the central channel through the nuclear pore complex for inorganic ions and small macromolecules
the structure of human 4f2hc ectodomain provides a model for homodimerization and electrostatic interaction with plasma membrane
p66shca and oxidative stress modulate myogenic differentiation and skeletal muscle regeneration after hind limb ischemia
role of the jak/stat pathway in the regulation of interleukin-8 transcription by oxidized phospholipids in vitro and in atherosclerosis in vivo
endoplasmic reticulum chaperones stabilize nicotinic receptor subunits and regulate receptor assembly
mitochondrial regulation of caspase activation by cytochrome oxidase and tetramethylphenylenediamine via cytosolic cytochrome c redox state
changes to the hiv long terminal repeat and to hiv integrase differentially impact hiv integrase assembly, activity, and the binding of strand transfer inhibitors
retrophosphorylation of mkk1 and mkk2 mapkks by the slt2 mapk in the yeast cell integrity pathway
comp acts as a catalyst in collagen fibrillogenesis
ccaat/enhancer-binding protein- participates in insulin-responsive expression of the factor vii gene
osmotically induced synthesis of the compatible solute hydroxyectoine is mediated by an evolutionarily conserved ectoine hydroxylase
lipopolysaccharide-mediated interferon regulatory factor activation involves tbk1-ikk-dependent lys63-linked polyubiquitination and phosphorylation of tank/i-traf
dynamic processing of recombinant dentin sialoprotein-phosphophoryn protein
circadian transcription depends on limiting amounts of the transcription co-activator nejire/cbp
characterization of recombinant cdr1, an arabidopsis aspartic proteinase involved in disease resistance
molecular mechanism of oxidative stress perception by the orp1 protein
cystic fibrosis transmembrane conductance regulator-independent phagosomal acidification in macrophages
basic fibroblast growth factor activates the mapk and nfb pathways that converge on elk-1 to control production of matrix metalloproteinase-13 by human adult articu..
p38 antagonizes p38 activity through c-jun-dependent ubiquitin-proteasome pathways in regulating ras transformation and stress response
the role of electrostatics in colicin nuclease domain translocation into bacterial cells
bis-methionine ligation to heme iron in the streptococcal cell surface protein shp facilitates rapid hemin transfer to htsa of the htsabc transporter
nmr solution structure of lipocalin-type prostaglandin d synthase
defective metabolic signaling in adenylate kinase ak1 gene knock-out hearts compromises post-ischemic coronary reflow
menin-mediated caspase 8 expression in suppressing multiple endocrine neoplasia type 1
s100b and s100a6 differentially modulate cell survival by interacting with distinct rage (receptor for advanced glycation end products) immunoglobulin domains
crystal structure and mutagenesis of the metallochaperone meab
the oxidase dsba folds a protein with a nonconsecutive disulfide
regulation of rgs2 and second messenger signaling in vascular smooth muscle cells by cgmp-dependent protein kinase
growth factor induction of cripto-1 shedding by glycosylphosphatidylinositol-phospholipase d and enhancement of endothelial cell migration
tetraspanin cd151 promotes cell migration by regulating integrin trafficking
cellular oligomerization of -synuclein is determined by the interaction of oxidized catechols with a c-terminal sequence
functional calcitonin gene-related peptide receptors are formed by the asymmetric assembly of a calcitonin receptor-like receptor homo-oligomer and a monomer of rec..
investigating the interaction between osteoprotegerin and receptor activator of nf-b or tumor necrosis factor-related apoptosis-inducing ligand
normal flux through atp-citrate lyase or fatty acid synthase is not required for glucose-stimulated insulin secretion
kinetic resolution of a tryptophan-radical intermediate in the reaction cycle of paracoccus denitrificans cytochrome c oxidase
a novel mechanism for substrate inhibition in mycobacterium tuberculosis d-3-phosphoglycerate dehydrogenase
structural and functional studies of the abundant tegument protein orf52 from murine gammaherpesvirus 68
nr4a orphan nuclear receptors modulate insulin action and the glucose transport system
(r)- and (s)-verapamil differentially modulate the multidrug-resistant protein mrp1
conditional deletion of gremlin causes a transient increase in bone formation and bone mass
role of the -helix 163-170 in factor xa catalytic activity
bk channels are linked to inositol 1,4,5-triphosphate receptors via lipid rafts
transcription termination factor rho can displace streptavidin from biotinylated rna
a calcium-gated lid and a large -roll sandwich are revealed by the crystal structure of extracellular lipase from serratia marcescens
holliday junction processing activity of the blm-topo iii-blap75 complex
the lipocalin 1-microglobulin has radical scavenging activity
presenilin 1 regulates epidermal growth factor receptor turnover and signaling in the endosomal-lysosomal pathway
functional characterization of premnaspirodiene oxygenase, a cytochrome p450 catalyzing regio- and stereo-specific hydroxylations of diverse sesquiterpene substrates
the -propensity of tau determines aggregation and synaptic loss in inducible mouse models of tauopathy
mammary epithelial-specific deletion of the focal adhesion kinase gene leads to severe lobulo-alveolar hypoplasia and secretory immaturity of the murine mammary gland
gestational choline deficiency causes global and igf2 gene dna hypermethylation by up-regulation of dnmt1 expression
identification and biochemical characterization of unique secretory nucleases of the human enteric pathogen, entamoeba histolytica
rsma is an anti-sigma factor that modulates its activity through a [2fe-2s] cluster cofactor
crystal structures of four types of human papillomavirus l1 capsid proteins
the eif2 kinases perk and pkr activate glycogen synthase kinase 3 to promote the proteasomal degradation of p53
human heat shock protein 70 enhances tumor antigen presentation through complex formation and intracellular antigen delivery without innate immune signaling
generation of multipotential mesendodermal progenitors from mouse embryonic stem cells via sustained wnt pathway activation
crystal structure of bacteriophage t4 5‘ nuclease in complex with a branched dna reveals how flap endonuclease-1 family nucleases bind their substrates
bone morphogenetic protein 2 functions via a conserved signaling pathway involving wnt4 to regulate uterine decidualization in the mouse and the human
pannexin1 channels contain a glycosylation site that targets the hexamer to the plasma membrane
mode of growth hormone action in osteoblasts
an endoplasmic reticulum transmembrane prolyl 4-hydroxylase is induced by hypoxia and acts on hypoxia-inducible factor
mps1 activation loop autophosphorylation enhances kinase activity
identification of a novel lysophospholipid acyltransferase in saccharomyces cerevisiae
a novel n-terminal isoform of the neuron-specific k-cl cotransporter kcc2
long-acting opioid antagonists disrupt receptor signaling and produce noncompetitive effects by activating c-jun n-terminal kinase
protein kinase c
uridylate-specific 3‘–5‘-exoribonucleases involved in uridylate-deletion rna editing in trypanosomatid mitochondria
membrane topology of the alg14 endoplasmic reticulum udp-glcnac transferase subunit
unraveling g protein-coupled receptor endocytosis pathways using real-time monitoring of agonist-promoted interaction between -arrestins and ap-2
variegin, a novel fast and tight binding thrombin inhibitor from the tropical bont tick
co-receptor requirements for fibroblast growth factor-19 signaling
s-adenosylmethionine-dependent protein methylation in mammalian cytosol via tyrphostin modification by catechol-o-methyltransferase
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