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生物物理学杂志2007年第07期封面 购买


the dpb4 subunit of isw2 is anchored to extranucleosomal dna
survivin down-regulation plays a crucial role in 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitor-induced apoptosis in cancer
the chli1 subunit of arabidopsis thaliana magnesium chelatase is a target protein of the chloroplast thioredoxin
structure of amidase from pseudomonas aeruginosa showing a trapped acyl transfer reaction intermediate state
essential role of heparan sulfate 2-o-sulfotransferase in chick limb bud patterning and development
microrna-124a regulates foxa2 expression and intracellular signaling in pancreatic -cell lines
activation of p61hck triggers wasp- and arp2/3-dependent actin-comet tail biogenesis and accelerates lysosomes
a dominant negative form of the transcription factor c-jun affects genes that have opposing effects on lipid homeostasis in mice
mitotic regulation of sirt2 by cyclin-dependent kinase 1-dependent phosphorylation
kinetic mechanism of the fastest motor protein, chara myosin
a histidine scan to probe the flexibility of the rat p2x2 receptor zinc-binding site
g-mediated prostacyclin production and camp-dependent protein kinase activation by endothelin-1 promotes vascular smooth muscle cell hypertrophy through inhibition ..
requirement of oxidation-dependent cd40 homodimers for cd154/cd40 bidirectional signaling
a dominant-negative form of mouse sox2 induces trophectoderm differentiation and progressive polyploidy in mouse embryonic stem cells
cd36 is important for fatty acid and cholesterol uptake by the proximal but not distal intestine
maspin binds to urokinase-type and tissue-type plasminogen activator through exosite-exosite interactions
amino acid changes within antenna helix are responsible for different regulatory preferences of human glutamate dehydrogenase isozymes
two isoforms of the t-cell intracellular antigen 1 (tia-1) splicing factor display distinct splicing regulation activities
eps8 facilitates cellular growth and motility of colon cancer cells by increasing the expression and activity of focal adhesion kinase
forkhead proteins are critical for bone morphogenetic protein-2 regulation and anti-tumor activity of resveratrol
murine orai2 splice variants form functional ca2+ release-activated ca2+ (crac) channels
tumor necrosis factor (tnf) stimulates map4k4 expression through tnf receptor 1 signaling to c-jun and activating transcription factor 2
role of amp kinase and ppar in the regulation of lipid and glucose metabolism in human skeletal muscle
nuclear import of the muc1-c oncoprotein is mediated by nucleoporin nup62
cloning and characterization of a functional human -aminobutyric acid (gaba) transporter, human gat-2
spxb regulates o-acetylation-dependent resistance of lactococcus lactis peptidoglycan to hydrolysis
mechanism of dynamitin-mediated disruption of dynactin
caspase-8 and c-flipl associate in lipid rafts with nf-b adaptors during t cell activation
heregulin-mediated erbb2-erk signaling activates hyaluronan synthases leading to cd44-dependent ovarian tumor cell growth and migration
cell type-specific post-translational modifications of mouse osteopontin are associated with different adhesive properties
golgi-associated maturation of very low density lipoproteins involves conformational changes in apolipoprotein b, but is not dependent on apolipoprotein e
functions of chondroitin sulfate/dermatan sulfate chains in brain development
a novel conserved nuclear localization signal is recognized by a group of yeast importins
differential regulation of basic helix-loop-helix factors mash1 and olig2 by -amyloid accelerates both differentiation and death of cultured neural stem/progenitor ..
abca2 deficiency results in abnormal sphingolipid metabolism in mouse brain
the prolyl isomerase pin1 affects che-1 stability in response to apoptotic dna damage
osteopontin overexpression inhibits in vitro re-endothelialization via integrin engagement
acrolein inhibits cytokine gene expression by alkylating cysteine and arginine residues in the nf-b1 dna binding domain
toward understanding the cationicity of defensins
molecular and structural characterization of the pezat chromosomal toxin-antitoxin system of the human pathogen streptococcus pneumoniae
ephrina1 activates a src/focal adhesion kinase-mediated motility response leading to rho-dependent actino/myosin contractility
the enterococcus faecalis mscramm ace binds its ligand by the collagen hug model
human xip1 (c2orf13) is a novel regulator of cellular responses to dna strand breaks
crystal structure of yegs, a homologue to the mammalian diacylglycerol kinases, reveals a novel regulatory metal binding site
s-nitrosylation-induced conformational change in blackfin tuna myoglobin
nephroblastoma overexpressed (nov) inhibits osteoblastogenesis and causes osteopenia
specificity in transmembrane helix-helix interactions mediated by aromatic residues
the sterol carrier protein scp-x/pro-scp-2 gene has transcriptional activity and regulates the alzheimer disease -secretase
a novel destruction sequence targets the meiotic regulator spo13 for anaphase-promoting complex-dependent degradation in anaphase i
nhe1 inhibition by amiloride- and benzoylguanidine-type compounds
cloning and functional characterization of human sodium-dependent organic anion transporter (slc10a6)
leukocyte antigen-related deficiency enhances insulin-like growth factor-1 signaling in vascular smooth muscle cells and promotes neointima formation in response to..
an arrhythmia susceptibility gene in caenorhabditis elegans
distinct sensor pathways in the hierarchical control of snat2, a putative amino acid transceptor, by amino acid availability
anthrax edema toxin inhibits endothelial cell chemotaxis via epac and rap1
signaling by a non-dissociated complex of g protein and subunits stimulated by a receptor-independent activator of g protein signaling, ags8
escherichia coli pria protein, two modes of dna binding and activation of atp hydrolysis
human ola1 defines an atpase subfamily in the obg family of gtp-binding proteins
structures of mycobacterium tuberculosis 1-deoxy-d-xylulose-5-phosphate reductoisomerase provide new insights into catalysis
the tautomeric half-reaction of bphd, a c-c bond hydrolase
singar1, a novel run domain-containing protein, suppresses formation of surplus axons for neuronal polarity
dna binding and phosphorylation induce conformational alterations in the kinase-inducible domain of creb
the crystal structure of the ivy 4-16:0-acp desaturase reveals structural details of the oxidized active site and potential determinants of regioselectivity
structural basis for type ii membrane protein binding by erm proteins revealed by the radixin-neutral endopeptidase 24.11 (nep) complex
phosphorylation-dependent regulation of stability and transforming potential of ets transcriptional factor ese-1 by p21-activated kinase 1
hydrogen bonding of 7,8-dihydro-8-oxodeoxyguanosine with a charged residue in the little finger domain determines miscoding events in sulfolobus solfataricus dna po..
the shuttling sr protein 9g8 plays a role in translation of unspliced mrna containing a constitutive transport element
regulation of phototropic signaling in arabidopsis via phosphorylation state changes in the phototropin 1-interacting protein nph3
molecular basis of transcriptional antiactivation
a systematic and comprehensive combinatorial approach to simultaneously improve the activity, reaction specificity, and thermal stability of p-hydroxybenzoate hydro..
localization of au-rich element-containing mrna in cytoplasmic granules containing exosome subunits
structures of staphylococcus aureus d-tagatose-6-phosphate kinase implicate domain motions in specificity and mechanism
activated platelets and monocytes generate four hydroxyphosphatidylethanolamines via lipoxygenase
mutational analysis of h3 and h4 n termini reveals distinct roles in nuclear import
the threonine that carries fucose, but not fucose, is required for cripto to facilitate nodal signaling
a novel role of group vib calcium-independent phospholipase a2 (ipla2) in the inducible expression of group iia secretory pla2 in rat fibroblastic cells
swi/snf activity is required for the repression of deoxyribonucleotide triphosphate metabolic enzymes via the recruitment of msin3b
spfh2 mediates the endoplasmic reticulum-associated degradation of inositol 1,4,5-trisphosphate receptors and other substrates in mammalian cells
skp1-cullin-f-box-dependent degradation of aah1p requires its interaction with the f-box protein saf1p
laeverin/aminopeptidase q, a novel bestatin-sensitive leucine aminopeptidase belonging to the m1 family of aminopeptidases
von willebrand factor type c domain-containing proteins regulate bone morphogenetic protein signaling through different recognition mechanisms
cell nuclei spin in the absence of lamin b1
control of t cell-mediated autoimmunity by metabolite flux to n-glycan biosynthesis
pras40 regulates mtorc1 kinase activity by functioning as a direct inhibitor of substrate binding
the interferons: 50 years after their discovery, there is much more to learn
the interferon regulatory factor family in host defense: mechanism of action
structural basis of lsd1-corest selectivity in histone h3 recognition
fyn-mediated phosphorylation of nr2b tyr-1336 controls calpain-mediated nr2b cleavage in neurons and heterologous systems
germ line gain of function with sos1 mutation in hereditary gingival fibromatosis
initiation of decay of bacillus subtilis trp leader rna
introns regulate the rate of unstable mrna decay
characterization of heme as activator of toll-like receptor 4
sodium-dependent extracellular accessibility of lys-84 in the sodium/dicarboxylate cotransporter
a key role for orphan nuclear receptor liver receptor homologue-1 in activation of fatty acid synthase promoter by liver x receptor
a c-terminal region of signal peptide peptidase defines a functional domain for intramembrane aspartic protease catalysis
functional role of extracellular loop cysteine residues of the epithelial na+ channel in na+ self-inhibition
primary structure, regioselectivity, and evolution of the membrane-bound fatty acid desaturases of claviceps purpurea
regulation of mammalian protein o-mannosylation
nedd4-2 catalyzes ubiquitination and degradation of cell surface enac
a ubiquitin-binding motif in the translesion dna polymerase rev1 mediates its essential functional interaction with ubiquitinated proliferating cell nuclear antigen..
residues surrounding arg336 and arg562 contribute to the disparate rates of proteolysis of factor viiia catalyzed by activated protein c
chain initiation in the leinamycin-producing hybrid nonribosomal peptide/polyketide synthetase from streptomyces atroolivaceus s-14
discovery, characterization, and kinetic analysis of an alditol oxidase from streptomyces coelicolor
formation of a dinitrosyl iron complex by nora, a nitric oxide-binding di-iron protein from ralstonia eutropha h16
sustained hydrogen peroxide induces iron uptake by transferrin receptor-1 independent of the iron regulatory protein/iron-responsive element network
fibrillogenic nuclei composed of p301l mutant tau induce elongation of p301l tau but not wild-type tau
in vivo functional analyses of the type ii acyl carrier proteins of fatty acid biosynthesis
the proline-rich akt substrate of 40 kda (pras40) is a physiological substrate of mammalian target of rapamycin complex 1
jun kinase delays caspase-9 activation by interaction with the apoptosome
agonist-modulated regulation of amp-activated protein kinase (ampk) in endothelial cells
the n-terminal arm of the helicobacter pylori ni2+-dependent transcription factor nikr is required for specific dna binding
o-linked glycosylation at threonine 27 protects the copper transporter hctr1 from proteolytic cleavage in mammalian cells
fission yeast rnf4 homologs are required for dna repair
effects of ph and low density lipoprotein (ldl) on pcsk9-dependent ldl receptor regulation
arkadia induces degradation of snon and c-ski to enhance transforming growth factor- signaling
characterization of the amino acids involved in substrate specificity of methionine sulfoxide reductase a
the ubiquitin ligase scf(trcp) regulates the degradation of the growth hormone receptor
ptip associates with mll3- and mll4-containing histone h3 lysine 4 methyltransferase complex
optimal combination of soluble factors for tissue engineering of permanent cartilage from cultured human chondrocytes
glutathione is recruited into the nucleus in early phases of cell proliferation
the 1.8 å crystal structure of pa2412, an mbth-like protein from the pyoverdine cluster of pseudomonas aeruginosa
a novel plant protein-disulfide isomerase involved in the oxidative folding of cystine knot defense proteins
enhanced skeletal muscle contraction with myosin light chain phosphorylation by a calmodulin-sensing kinase
the mig-2/integrin interaction strengthens cell-matrix adhesion and modulates cell motility
ceramide-1-phosphate binds group iva cytosolic phospholipase a2 via a novel site in the c2 domain
bard1 translocation to mitochondria correlates with bax oligomerization, loss of mitochondrial membrane potential, and apoptosis
regulation of secreted frizzled-related protein-1 by heparin
hypoxia-inducible factor 1 is regulated by the mammalian target of rapamycin (mtor) via an mtor signaling motif
pancreatic insulin secretion in rats fed a soy protein high fat diet depends on the interaction between the amino acid pattern and isoflavones
mechanism of inhibition of sequestration of protein kinase c /ii by ceramide
-arrestin-dependent regulation of the cofilin pathway downstream of protease-activated receptor-2
heme oxygenase-1 protein localizes to the nucleus and activates transcription factors important in oxidative stress
grk2 negatively regulates glycogen synthesis in mouse liver fl83b cells
selective inhibitory effects of smad6 on bone morphogenetic protein type i receptors
the extremely conserved c-terminal region of reelin is not necessary for secretion but is required for efficient activation of downstream signaling
heat shock protein 75 (trap1) antagonizes reactive oxygen species generation and protects cells from granzyme m-mediated apoptosis
inducible hyaluronan production reveals differential effects on prostate tumor cell growth and tumor angiogenesis
fatty acid transport protein 4 is the principal very long chain fatty acyl-coa synthetase in skin fibroblasts
conserved surface features form the double-stranded rna binding site of non-structural protein 1 (ns1) from influenza a and b viruses
organelle targeting of myosin xi is mediated by two globular tail subdomains with separate cargo binding sites
mast cell-restricted tryptases: structure and function in inflammation and pathogen defense
infectious bursal disease virus, a non-enveloped virus, possesses a capsid-associated peptide that deforms and perforates biological membranes
dual subcellular localization in the endoplasmic reticulum and peroxisomes and a vital role in protecting against oxidative stress of fatty aldehyde dehydrogenase a..
structure of an atypical orphan response regulator protein supports a new phosphorylation-independent regulatory mechanism
rescue of a nephrogenic diabetes insipidus-causing vasopressin v2 receptor mutant by cell-penetrating peptides
atp-binding modes and functionally important interdomain bonds of sarcoplasmic reticulum ca2+-atpase revealed by mutation of glycine 438, glutamate 439, and arginin..
rotational catalysis of escherichia coli atp synthase f1 sector
molecular recognition and interfacial catalysis by the essential phosphatidylinositol mannosyltransferase pima from mycobacteria
wnt/-catenin signaling is a component of osteoblastic bone cell early responses to load-bearing and requires estrogen receptor
splicing factor 3b subunit 4 binds bmpr-ia and inhibits osteochondral cell differentiation
identification and characterization of cannabinoids that induce cell death through mitochondrial permeability transition in cannabis leaf cells
iqgap1 binds rap1 and modulates its activity
intranuclear protein transduction through a nucleoside salvage pathway
activation of 5‘-amp-activated kinase with diabetes drug metformin induces casein kinase i (cki)-dependent degradation of clock protein mper2
catalytic activity is not required for secreted pcsk9 to reduce low density lipoprotein receptors in hepg2 cells
acetylated histone tail peptides induce structural rearrangements in the rsc chromatin remodeling complex
the mast cell-restricted tryptase mmcp-6 has a critical immunoprotective role in bacterial infections
regulation of lipid flux between liver and adipose tissue during transient hepatic steatosis in carnitine-depleted rats
two saccharomyces cerevisiae jmjc domain proteins demethylate histone h3 lys36 in transcribed regions to promote elongation
inhibition of the activation of multiple serine proteases with a cathepsin c inhibitor requires sustained exposure to prevent pro-enzyme processing
targeting host cell furin proprotein convertases as a therapeutic strategy against bacterial toxins and viral pathogens
transcriptional regulation of the bovine leukemia virus promoter by the cyclic amp-response element modulator isoform
functional sequestration of transcription factor activity by repetitive dna
substrate-specific interactions with the heme-bound oxygen molecule of nitric-oxide synthase
regulation of transcript elongation through cooperative and ordered recruitment of cofactors
differential repression by freud-1/cc2d1a at a polymorphic site in the dopamine-d2 receptor gene
caveolin-associated accumulation of globotriaosylceramide in the vascular endothelium of -galactosidase a null mice
specific protein domains mediate cooperative assembly of hur oligomers on au-rich mrna-destabilizing sequences
analysis of a parallel branch in the mitomycin biosynthetic pathway involving the mitn-encoded aziridine n-methyltransferase
aquaporin-1 channel function is positively regulated by protein kinase c
differential function of ptp and ptp y789f in t cells and regulation of ptp phosphorylation at tyr-789 by cd45
a second proliferating cell nuclear antigen loader complex, ctf18-replication factor c, stimulates dna polymerase activity
role of lrat on the retinoid isomerase activity and membrane association of rpe65
characterization of anti-heparan sulfate phage display antibodies ao4b08 and hs4e4
purification and characterization of cellular proteins associated with histone h4 tails
atccma interacts with atccmb to form a novel mitochondrial abc transporter involved in cytochrome c maturation in arabidopsis
sequential regulation of diacylglycerol acyltransferase 2 expression by caat/enhancer-binding protein (c/ebp) and c/ebp during adipogenesis
hyaluronan export by the abc transporter mrp5 and its modulation by intracellular cgmp
timp-3 inhibition of adamts-4 (aggrecanase-1) is modulated by interactions between aggrecan and the c-terminal domain of adamts-4
mechanism of reversal of phospholamban inhibition of the cardiac ca2+-atpase by protein kinase a and by anti-phospholamban monoclonal antibody 2d12
determinants of the anesthetic sensitivity of two-pore domain acid-sensitive potassium channels
the hepatitis e virus orf3 protein protects cells from mitochondrial depolarization and death
nucleic acid unwinding by hepatitis c virus and bacteriophage t7 helicases is sensitive to base pair stability
the metarhizium anisopliae perilipin homolog mpl1 regulates lipid metabolism, appressorial turgor pressure, and virulence
c1 inhibitor serpin domain structure reveals the likely mechanism of heparin potentiation and conformational disease
sterol regulatory element-binding protein-2- and liver x receptor-driven dual promoter regulation of hepatic abc transporter a1 gene expression
recognition mechanism of galectin-4 for cholesterol 3-sulfate
interactions of human rad54 protein with branched dna molecules
evidence that the heme regulatory motifs in heme oxygenase-2 serve as a thiol/disulfide redox switch regulating heme binding
selective inhibition of cav3.3 t-type calcium channels by gq/11-coupled muscarinic acetylcholine receptors
bacillus thuringiensis cry1ab mutants affecting oligomer formation are non-toxic to manduca sexta larvae
phosphorylation of both nucleoplasmin domains is required for activation of its chromatin decondensation activity
inhibition of phosphatidylinositol-3-oh kinase/akt signaling impairs dna repair in glioblastoma cells following ionizing radiation
structure of escherichia coli lytic transglycosylase mlta with bound chitohexaose
acetylation of smad2 by the co-activator p300 regulates activin and transforming growth factor response
foxo1 regulates the expression of 4e-bp1 and inhibits mtor signaling in mammalian skeletal muscle
identification of essential catalytic residues of the cyclase nisc involved in the biosynthesis of nisin
nitric oxide is critical for inducing phosphatidic acid accumulation in xylanase-elicited tomato cells
distinct uptake mechanisms but similar intracellular processing of two different toll-like receptor ligand-peptide conjugates in dendritic cells
specificity in beta cell expression of l-3-hydroxyacyl-coa dehydrogenase, short chain, and potential role in down-regulating insulin release
critical role of the heme axial ligand, met95, in locking catalysis of the phosphodiesterase from escherichia coli (ec dos) toward cyclic digmp
d1 and d2 dopamine receptor expression is regulated by direct interaction with the chaperone protein calnexin
gapex-5 mediates ubiquitination, trafficking, and degradation of epidermal growth factor receptor
protein kinase c abrogates the proapoptotic function of bax through phosphorylation
functional genomic studies of uropathogenic escherichia coli and host urothelial cells when intracellular bacterial communities are assembled
a potential dimerization region of dcamta is critical for termination of fly visual response
akt-mediated liver growth promotes induction of cyclin e through a novel translational mechanism and a p21-mediated cell cycle arrest
atherogenic phospholipids attenuate osteogenic signaling by bmp-2 and parathyroid hormone in osteoblasts
amyotrophic lateral sclerosis-associated copper/zinc superoxide dismutase mutations preferentially reduce the repulsive charge of the proteins
ca2+-dependent activator protein for secretion 1 is critical for constitutive and regulated exocytosis but not for loading of transmitters into dense core vesicles
small molecule inhibitors of a glycoside hydrolase attenuate inducible ampc-mediated -lactam resistance
the active conformation of -arrestin
detailed structural insights into the p97-npl4-ufd1 interface
crotamine mediates gene delivery into cells through the binding to heparan sulfate proteoglycans
phosphorylated galectin-3 mediates tumor necrosis factor-related apoptosis-inducing ligand signaling by regulating phosphatase and tensin homologue deleted on chrom..
mitochondrial reactive oxygen species signal hepatocyte steatosis by regulating the phosphatidylinositol 3-kinase cell survival pathway
strand opening-deficient escherichia coli rna polymerase facilitates investigation of closed complexes with promoter dna
promoter-dependent effect of ikk on nf-b/p65 dna binding
a critical role for ib kinase in metallothionein-1 expression and protection against arsenic toxicity
a transition state analogue of 5‘-methylthioadenosine phosphorylase induces apoptosis in head and neck cancers
mechanism of diacylglycerol-induced membrane targeting and activation of protein kinase c
role of a carboxylesterase in herbicide bioactivation in arabidopsis thaliana
nmr investigation of tyr105 mutants in tem-1 -lactamase
role of laminin terminal globular domains in basement membrane assembly
empty class ii major histocompatibility complex created by peptide photolysis establishes the role of dm in peptide association
human nuf2 interacts with centromere-associated protein e and is essential for a stable spindle microtubule-kinetochore attachment
functional similarity between the chloroplast translocon component, tic40, and the human co-chaperone, hsp70-interacting protein (hip)
multisubunit rna polymerases melt only a single dna base pair downstream of the active site
the non-mevalonate pathway of isoprenoid precursor biosynthesis
functional characterization of atatm1, atatm2, and atatm3, a subfamily of arabidopsis half-molecule atp-binding cassette transporters implicated in iron homeostasis
sumoylation of oct4 enhances its stability, dna binding, and transactivation
regulation of foxo3a/-catenin/gsk-3 signaling by 3,3‘-diindolylmethane contributes to inhibition of cell proliferation and induction of apoptosis in prostate cance..
lysophosphatidic acid regulates trafficking of 2-adrenergic receptors
identification of a minimal myosin va binding site within an intrinsically unstructured domain of melanophilin
the interaction of endoglin with -arrestin2 regulates transforming growth factor--mediated erk activation and migration in endothelial cells
the p21-activated kinase 3 implicated in mental retardation regulates spine morphogenesis through a cdc42-dependent pathway
contribution of the conserved amino acids of the melanocortin-4 receptor in d-[nle4,phe7]--melanocyte-stimulating hormone binding and signaling
regulation of adipocyte lipolysis by degradation of the perilipin protein
short-term treatment of raw264.7 macrophages with adiponectin increases tumor necrosis factor- (tnf-) expression via erk1/2 activation and egr-1 expression
properties of actin from the fission yeast schizosaccharomyces pombe and interaction with fission yeast profilin
plasminogen activator inhibitor-1 is an inhibitor of factor vii-activating protease in patients with acute respiratory distress syndrome
the fission yeast jmj2 reverses histone h3 lysine 4 trimethylation
regulation of the sodium/sulfate co-transporter by farnesoid x receptor
activation and inhibition of photoreceptor guanylyl cyclase by guanylyl cyclase activating protein 1 (gcap-1)
kinetic characterization of tail swing steps in the atpase cycle of dictyostelium cytoplasmic dynein
cyclic amp-dependent protein kinase phosphorylation of drp1 regulates its gtpase activity and mitochondrial morphology
efficient inhibition of class a and class d -lactamases by michaelis complexes
miconazole induces changes in actin cytoskeleton prior to reactive oxygen species induction in yeast
hsp27 regulates akt activation and polymorphonuclear leukocyte apoptosis by scaffolding mk2 to akt signal complex
use of biotin derivatives to probe conformational changes in proteins
bax inhibitor-1 regulates endoplasmic reticulum stress-associated reactive oxygen species and heme oxygenase-1 expression
identification of a vacuole-associated metalloreductase and its role in ctr2-mediated intracellular copper mobilization
phospholipase d1 production of phosphatidic acid at the plasma membrane promotes exocytosis of large dense-core granules at a late stage
identification of a soluble diacylglycerol kinase required for lipoteichoic acid production in bacillus subtilis
characterization of cis-autoproteolysis of polycystin-1, the product of human polycystic kidney disease 1 gene
blue light induces radical formation and autophosphorylation in the light-sensitive domain of chlamydomonas cryptochrome
biosynthesis of (r)--tyrosine and its incorporation into the highly cytotoxic chondramides produced by chondromyces crocatus
control and regulation of kple1 prophage site-specific recombination
doc2 is a novel munc18c-interacting partner and positive effector of syntaxin 4-mediated exocytosis
inflammatory signaling pathways regulating apoe gene expression in macrophages
amino acid transport in schistosomes
selective desensitization of growth factor signaling by cell adhesion to fibronectin
diminished gata4 protein levels contribute to hyperglycemia-induced cardiomyocyte injury
retinoic acid-inducible gene-i and interferon- promoter stimulator-1 augment proapoptotic responses following mammalian reovirus infection via interferon regulatory..
heparan sulfate degradation products can associate with oxidized proteins and proteasomes
ccaat enhancer-binding protein regulates constitutive gene expression during late stages of monocyte to macrophage differentiation
induction of base damages representing a high risk site for double-strand dna break formation in genomic dna by exposure of cells to dna damaging agents
properties of rna polymerase ii elongation complexes before and after the p-tefb-mediated transition into productive elongation
the melanization reaction is not required for survival of anopheles gambiae mosquitoes after bacterial infections
sequential opening of mitochondrial ion channels as a function of glutathione redox thiol status
grb10 and active raf-1 kinase promote bad-dependent cell survival
evidence against functional interaction between aquaporin-4 water channels and kir4.1 potassium channels in retinal müller cells
possible role for intracellular cholesteryl ester transfer protein in adipocyte lipid metabolism and storage
characterization of a factor xa binding site on factor va near the arg-506 activated protein c cleavage site
expression of human protein phosphatase-1 in saccharomyces cerevisiae highlights the role of phosphatase isoforms in regulating eukaryotic functions
active adp-ribosylation factor-1 (arf1) is required for mitotic golgi fragmentation
degradation of hsp70 and other mrnas in drosophila via the 5‘–3‘ pathway and its regulation by heat shock
tripartite chimeras comprising functional domains derived from the cytosolic nadph oxidase components p47phox, p67phox, and rac1 elicit activator-independent supero..
structural mechanism for substrate inhibition of the adenosine 5‘-phosphosulfate kinase domain of human 3‘-phosphoadenosine 5‘-phosphosulfate synthetase 1 and it..
replacement of nonmuscle myosin ii-b with ii-a rescues brain but not cardiac defects in mice
transforming growth factor-1 induces an epithelial-to-mesenchymal transition state in mouse hepatocytes in vitro
free oligosaccharides in the cytosol of caenorhabditis elegans are generated through endoplasmic reticulum-golgi trafficking
redox regulation of camp-dependent protein kinase signaling
sparc regulates processing of procollagen i and collagen fibrillogenesis in dermal fibroblasts
nuclear factor-e2-related factor-1 mediates ascorbic acid induction of osterix expression via interaction with antioxidant-responsive element in bone cells
detection of reactive oxygen species-sensitive thiol proteins by redox difference gel electrophoresis
specific recognition of the -10 promoter element by the free rna polymerase subunit
structural and functional characterization of a novel t cell receptor co-regulatory protein complex, cd97-cd55
human peroxiredoxin 1 and 2 are not duplicate proteins
mmp25 (mt6-mmp) is highly expressed in human colon cancer, promotes tumor growth, and exhibits unique biochemical properties
regulation of the pro-apoptotic scaffolding protein posh by akt
structure of phenylalanine hydroxylase from colwellia psychrerythraea 34h, a monomeric cold active enzyme with local flexibility around the active site and high ove..
survival factor withdrawal-induced apoptosis of tf-1 cells involves a trb2-mcl-1 axis-dependent pathway
membrane glycoprotein m6a interacts with the µ-opioid receptor and facilitates receptor endocytosis and recycling
functional silencing of tata-binding protein (tbp) by a covalent linkage of the n-terminal domain of tbp-associated factor 1
biochemical characterization of thepolysialic acid-specific o-acetyltransferase neuo of escherichia coli k1
structures of 5-methylthioribose kinase reveal substrate specificity and unusual mode of nucleotide binding
assessing the role of the active-site cysteine ligand in the superoxide reductase from desulfoarculus baarsii
crystal structures of saccharomyces cerevisiae n-myristoyltransferase with bound myristoyl-coa and inhibitors reveal the functional roles of the n-terminal region
cathespin h is an fgf10 target involved in bmp4 degradation during lung branching morphogenesis
abnormal collagen fibrils in cartilage of matrilin-1/matrilin-3-deficient mice
inhibition of a specific n-glycosylation activity results in attenuation of breast carcinoma cell invasiveness-related phenotypes
tumor progression locus-2 is a critical regulator of pancreatic and lung inflammation during acute pancreatitis
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