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reovirus binding determinants in junctional adhesion molecule-a
subcellular localization and physiological significance of intracellular mannan-binding protein
binding of pleomorphic adenoma gene-like 2 to the tumor necrosis factor (tnf)--responsive region of the ncf2 promoter regulates p67phox expression and nadph oxidase..
the src-like adaptor protein 2 regulates colony-stimulating factor-1 receptor signaling and down-regulation
calcium inhibition and calcium potentiation of orai1, orai2, and orai3 calcium release-activated calcium channels
group g streptococcal igg binding molecules fog and protein g have different impacts on opsonization by c1q
both sphingomyelin synthases sms1 and sms2 are required for sphingomyelin homeostasis and growth in human hela cells
expression of the rat sterol regulatory element-binding protein-1c gene in response to insulin is mediated by increased transactivating capacity of specificity prot..
the nuclear export signal of splicing factor uap56p interacts with nuclear pore-associated protein rae1p for mrna export in schizosaccharomyces pombe
ataxia-telangiectasia mutated (atm)-dependent activation of atr occurs through phosphorylation of topbp1 by atm
electron transport pathway for a streptomyces cytochrome p45
cd40 ligand-mediated activation of the de novo relb nf-b synthesis pathway in transformed b cells promotes rescue from apoptosis
biogenesis of a respiratory complex is orchestrated by a single accessory protein
activation of bestrophin cl- channels is regulated by c-terminal domains
tumor necrosis factor- stimulates focal adhesion kinase activity required for mitogen-activated kinase-associated interleukin 6 expression
evidence for a pro-oxidant intermediate in the assembly of cytochrome oxidase
allosteric regulation of seca
atp-sensitive potassium channel in mitochondria of the eukaryotic microorganism acanthamoeba castellanii
three-way stabilization of the covalent intermediate in amylomaltase, an -amylase-like transglycosylase
scavenger receptor c-type lectin binds to the leukocyte cell surface glycan lewisx by a novel mechanism
the wnt5a/protein kinase c pathway mediates motility in melanoma cells via the inhibition of metastasis suppressors and initiation of an epithelial to mesenchymal t..
potential role for phosphorylation in differential regulation of the assembly of dynein light chains
the integrin binding site 2 (ibs2) in the talin rod domain is essential for linking integrin subunits to the cytoskeleton
immobilization of bioactive fibroblast growth factor-2 into cubic proteinous microcrystals (bombyx mori cypovirus polyhedra) that are insoluble in a physiological c..
akt-dependent hspb1 (hsp27) activity in epidermal differentiation
structure of the human lung cytochrome p450 2a13
insights into the mechanism of partial agonism
a proteomic analysis of ataxia telangiectasia-mutated (atm)/atm-rad3-related (atr) substrates identifies the ubiquitin-proteasome system as a regulator for dna dama..
regulation of greb1 transcription by estrogen receptor through a multipartite enhancer spread over 20 kb of upstream flanking sequences
butein, a tetrahydroxychalcone, inhibits nuclear factor (nf)-b and nf-b-regulated gene expression through direct inhibition of ib kinase on cysteine 179 residue
mitotic phosphorylation of the anaphase-promoting complex inhibitory subunit mnd2 is necessary for efficient progression through meiosis i
roles for the human atp-dependent lon protease in mitochondrial dna maintenance
certain pairs of ubiquitin-conjugating enzymes (e2s) and ubiquitin-protein ligases (e3s) synthesize nondegradable forked ubiquitin chains containing all possible is..
dna polymerases and function in the same genetic pathway to generate mutations at a/t during somatic hypermutation of ig genes
a specific adaptation in the a subunit of thermoalkaliphilic f1fo-atp synthase enables atp synthesis at high ph but not at neutral ph values
systematic analysis of the entire second extracellular loop of the v1a vasopressin receptor
thiazole synthase from escherichia coli
an assembled complex iv maintains the stability and activity of complex i in mammalian mitochondria
the proton electrochemical gradient across the plasma membrane of yeast is necessary for phospholipid flip
elmod2 is an arl2 gtpase-activating protein that also acts on arfs
po2-dependent differential regulation of multidrug resistance 1 gene expression by the c-jun nh2-terminal kinase pathway
major histocompatibility complex class i-erp57-tapasin interactions within the peptide-loading complex
n-methyl-d-aspartate receptor-dependent regulation of the glutamate transporter excitatory amino acid carrier 1
formation and function of flavin anion radical in cryptochrome 1 blue-light photoreceptor of monarch butterfly
phosphorylation of human ctp synthetase 1 by protein kinase c
evidence for small ubiquitin-like modifier-dependent nuclear import of the thymidylate biosynthesis pathway
mammalian sec16/p250 plays a role in membrane traffic from the endoplasmic reticulum
nox1 redox signaling mediates oncogenic ras-induced disruption of stress fibers and focal adhesions by down-regulating rho
human trbp and pact directly interact with each other and associate with dicer to facilitate the production of small interfering rna
selective perturbation of the myosin recovery stroke by point mutations at the base of the lever arm affects atp hydrolysis and phosphate release
scleraxis and nfatc regulate the expression of the pro-1(i) collagen gene in tendon fibroblasts
identification of an adam2-adam3 complex on the surface of mouse testicular germ cells and cauda epididymal sperm
a -1,2-xylosyltransferase from cryptococcus neoformans defines a new family of glycosyltransferases
identification of the substrate binding sites within the yeast mitochondrial citrate transport protein
thermodynamic investigation of the role of contact residues of -lactamase-inhibitory protein for binding to tem-1 -lactamase
peroxisomal proliferator-activated receptor--dependent inhibition of endothelial cell proliferation and tumorigenesis
effects of single nucleotide polymorphisms on toll-like receptor 3 activity and expression in cultured cells
cell cycle-dependent expression of centrosomal ninein-like protein in human cells is regulated by the anaphase-promoting complex
interaction sites between the slo1 pore and the nh2 terminus of the 2 subunit, probed with a three-residue sensor
key role of amino acid residues in the dimerization and catalytic activation of the autolysin lyta, an important virulence factor in streptococcus pneumoniae
comparative analysis of two udp-glucose dehydrogenases in pseudomonas aeruginosa pao1
movements of the tolr c-terminal domain depend on tolqr ionizable key residues and regulate activity of the tol complex
interorganelle trafficking of ceramide is regulated by phosphorylation-dependent cooperativity between the ph and start domains of cert
exploring molecular oxygen pathways in hansenula polymorpha copper-containing amine oxidase
localization of an nh2-terminal disease-causing mutation hot spot to the “clamp“ region in the three-dimensional structure of the cardiac ryanodine receptor
structure and function of dnaa n-terminal domains
crystal structure of human cytosolic 5‘-nucleotidase ii
-conotoxin and tricyclic antidepressant interactions at the norepinephrine transporter define a new transporter model
activation of poly(adp)-ribose polymerase (parp-1) induces release of the pro-inflammatory mediator hmgb1 from the nucleus
anti-desmoglein 3 (dsg3) monoclonal antibodies deplete desmosomes of dsg3 and differ in their dsg3-depleting activities related to pathogenicity
transcriptional activators and repressors for the neuron-specific expression of a metabotropic glutamate receptor
mutational and structural studies aimed at characterizing the monomer of hiv-1 protease and its precursor
the anti-inflammatory effects of selenium are mediated through 15-deoxy-12,14-prostaglandin j2 in macrophages
liver fatty acid-binding protein initiates budding of pre-chylomicron transport vesicles from intestinal endoplasmic reticulum
biological cross-talk between wnk1 and the transforming growth factor -smad signaling pathway
functional analysis of activating receptor lmir4 as a counterpart of inhibitory receptor lmir3
nf-b p50 and p52 regulate receptor activator of nf-b ligand (rankl) and tumor necrosis factor-induced osteoclast precursor differentiation by activating c-fos and n..
prostaglandin endoperoxide h synthases
mutation of a conserved asparagine in the i-like domain promotes constitutively active integrins l2 and iib3
definition by functional and structural analysis of two malonyl-coa sites in carnitine palmitoyltransferase 1a
growth-dependent phosphorylation of the ptsn (eiintr) protein of pseudomonas putida
alkalizing drugs induce accumulation of amyloid precursor protein by-products in luminal vesicles of multivesicular bodies
the structure of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase provides insights into the mechanism of uric acid degradation
replication fork reversal occurs spontaneously after digestion but is constrained in supercoiled domains
up-regulation of loricrin expression by cell adhesion molecule nectin-1 through rap1-erk signaling in keratinocytes
identification of a novel prostaglandin reductase reveals the involvement of prostaglandin e2 catabolism in regulation of peroxisome proliferator-activated receptor..
very long-chain polyunsaturated fatty acids are the major acyl groups of sphingomyelins and ceramides in the head of mammalian spermatozoa
ceramides and sphingomyelins with high proportions of very long-chain polyunsaturated fatty acids in mammalian germ cells
intersectin-1s regulates the mitochondrial apoptotic pathway in endothelial cells
calcineurin activation is only one calcium-dependent step in cytotoxic t lymphocyte granule exocytosis
common inhibitory serine sites phosphorylated by irs-1 kinases, triggered by insulin and inducers of insulin resistance
nicotinic acid receptor agonists differentially activate downstream effectors
association of the tim14·tim16 subcomplex with the tim23 translocase is crucial for function of the mitochondrial protein import motor
properties of rna polymerase bypass mutants
lithium desensitizes brain mitochondria to calcium, antagonizes permeability transition, and diminishes cytochrome c release
energy depletion inhibits phosphatidylinositol 3-kinase/akt signaling and induces apoptosis via amp-activated protein kinase-dependent phosphorylation of irs-1 at s..
homooligomeric and heterooligomeric associations between k+-cl- cotransporter isoforms and between k+-cl- and na+-k+-cl- cotransporters
receptor activity-modifying proteins 2 and 3 have distinct physiological functions from embryogenesis to old age
learning-induced glutamate receptor phosphorylation resembles that induced by long term potentiation
transglutaminase 2 kinase activity facilitates protein kinase a-induced phosphorylation of retinoblastoma protein
atplai is an acyl hydrolase involved in basal jasmonic acid production and arabidopsis resistance to botrytis cinerea
repulsive guidance molecule rgma alters utilization of bone morphogenetic protein (bmp) type ii receptors by bmp2 and bmp4
the metallo--lactamase gob is a mono-zn(ii) enzyme with a novel active site
proteolytic activities of human adamts-
asp-120 locates zn2 for optimal metallo--lactamase activity
recognition of hyaluronan released in sterile injury involves a unique receptor complex dependent on toll-like receptor 4, cd44, and md-2
characterization of arabidopsis thaliana sufe2 and sufe
epitope analysis of the malaria surface antigen pfs48/45 identifies a subdomain that elicits transmission blocking antibodies
necl-5/poliovirus receptor interacts in cis with integrin v3 and regulates its clustering and focal complex formation
a novel pathway to enhance adipocyte differentiation of 3t3-l1 cells by up-regulation of lipocalin-type prostaglandin d synthase mediated by liver x receptor-activa..
stress-responsive gln3 localization in saccharomyces cerevisiae is separable from and can overwhelm nitrogen source regulation
mass spectrometry reveals the missing links in the assembly pathway of the bacterial 20 s proteasome
the ding protein from escherichia coli is a structure-specific helicase
glutathione supplementation potentiates hypoxic apoptosis by s-glutathionylation of p65-nfb
the effect of hinge mutations on effector binding and domain rotation in escherichia coli d-3-phosphoglycerate dehydrogenase
serine 64 phosphorylation enhances the antiapoptotic function of mcl-1
the plant homeodomain fingers of fission yeast msc1 exhibit e3 ubiquitin ligase activity
mode of membrane interaction and fusogenic properties of a de novo transmembrane model peptide depend on the length of the hydrophobic core
human tribbles-1 controls proliferation and chemotaxis of smooth muscle cells via mapk signaling pathways
stabilization of p73 by nuclear ib kinase- mediates cisplatin-induced apoptosis
characterization of a novel cell wall-anchored protein with carboxylesterase activity required for virulence in mycobacterium tuberculosis
regulated externalization of phosphatidylserine at the cell surface
epithelial na+ channel stimulation by n-3 fatty acids requires proximity to a membrane-bound a-kinase-anchoring protein complexed with protein kinase a and phosphod..
fibrillogenic oligomers of human cystatin c are formed by propagated domain swapping
activation of mps1 promotes transforming growth factor--independent smad signaling
cd40-40l signaling in vascular inflammation
dnase x is a glycosylphosphatidylinositol-anchored membrane enzyme that provides a barrier to endocytosis-mediated transfer of a foreign gene
eis (enhanced intracellular survival) protein of mycobacterium tuberculosis disturbs the cross regulation of t-cells
a novel regulatory role for stromal-derived factor-1 signaling in bone morphogenic protein-2 osteogenic differentiation of mesenchymal c2c12 cells
induction of the gal pathway and cellulase genes involves no transcriptional inducer function of the galactokinase in hypocrea jecorina
microtubule association of the neuronal p35 activator of cdk5
role of scarf and its binding target proteins in epidermal calcium homeostasis
silencing of insulin-like growth factor-binding protein-2 in human glioblastoma cells reduces both invasiveness and expression of progression-associated gene cd24
ajulemic acid, a synthetic nonpsychoactive cannabinoid acid, bound to the ligand binding domain of the human peroxisome proliferator-activated receptor
transcriptional regulation of cidea, mitochondrial cell death-inducing dna fragmentation factor -like effector a, in mouse liver by peroxisome proliferator-activate..
a new mode of regulation of n-type inactivation in a caenorhabditis elegans voltage-gated potassium channel
binding of proprotein convertase subtilisin/kexin type 9 to epidermal growth factor-like repeat a of low density lipoprotein receptor decreases receptor recycling a..
tissue-specific autophagy alterations and increased tumorigenesis in mice deficient in atg4c/autophagin-3
aberrant association of promyelocytic leukemia protein-retinoic acid receptor- with coactivators contributes to its ability to regulate gene expression
a quantitative kinetic model for the in vitro assembly of intermediate filaments from tetrameric vimentin
structure-based mapping of daf active site residues that accelerate the decay of c3 convertases
the rheb switch 2 segment is critical for signaling to target of rapamycin complex 1
top-down phenomics of arabidopsis thaliana
a molecular link between e2f-1 and the mapk cascade
biochemical and genetic studies of ubr3, a ubiquitin ligase with a function in olfactory and other sensory systems
structural basis of the catalytic reaction mechanism of novel 1,2--l-fucosidase from bifidobacterium bifidum
transgenic rnai depletion of claudin-16 and the renal handling of magnesium
a novel modulatory mechanism of transforming growth factor- signaling through decorin and lrp-1
calpain inhibition is sufficient to suppress aggregation of polyglutamine-expanded ataxin-3
energy depletion protects candida albicans against antimicrobial peptides by rigidifying its cell membrane
a novel phosphoinositide 3-kinase-dependent pathway for angiotensin ii/at-1 receptor-mediated induction of collagen synthesis in mes-13 mesangial cells
differential requirement of p2x7 receptor and intracellular k+ for caspase-1 activation induced by intracellular and extracellular bacteria
the farnesyltransferase inhibitor lonafarnib induces ccaat/enhancer-binding protein homologous protein-dependent expression of death receptor 5, leading to inductio..
protection of dna ends by telomeric 3‘ g-tail sequences
calcium induces increases in peroxisome proliferator-activated receptor coactivator-1 and mitochondrial biogenesis by a pathway leading to p38 mitogen-activated pro..
squalene synthase, a determinant of raft-associated cholesterol and modulator of cancer cell proliferation
stargazin interaction with -amino-3-hydroxy-5-methyl-4-isoxazole propionate (ampa) receptors is critically dependent on the amino acid at the narrow constriction of..
sdrf, a staphylococcus epidermidis surface protein, binds type i collagen
molecular characterization of the tax-containing htlv-1 enhancer complex reveals a prominent role for creb phosphorylation in tax transactivation
ethanol induces cholesterol efflux and up-regulates atp-binding cassette cholesterol transporters in fetal astrocytes
collaborator of stat6 (coast6)-associated poly(adp-ribose) polymerase activity modulates stat6-dependent gene transcription
helicobacter pylori stimulates gastric epithelial cell mmp-1 secretion via caga-dependent and -independent erk activation
archease from pyrococcus abyssi improves substrate specificity and solubility of a trna m5c methyltransferase
scrapie infection of prion protein-deficient cell line upon ectopic expression of mutant prion proteins
awaking tim22, a dynamic ligand-gated channel for protein insertion in the mitochondrial inner membrane
identification of a streptococcal octapeptide motif involved in acute rheumatic fever
molecular characterization of the ran-binding zinc finger domain of nup153
c-fms tyrosine 559 is a major mediator of m-csf-induced proliferation of primary macrophages
role of the synthase domain of ags1p in cell wall -glucan biosynthesis in fission yeast
structure shows that a glycosaminoglycan and protein recognition site in factor h is perturbed by age-related macular degeneration-linked single nucleotide polymorp..
ubiquitous lens -, -, and -crystallins accumulate in anuran cornea as corneal crystallins
catsper, a novel transmembrane protein in the catsper channel complex
n-terminal tyrosine modulation of the endocytic adaptor function of the -arrestins
directed evolution of ribosomal protein s1 for enhanced translational efficiency of high gc rhodopseudomonas palustris dna in escherichia coli
identification of a gastrin response element in the vesicular monoamine transporter type 2 promoter and requirement of 20 s proteasome subunits for transcriptional ..
functional characterization of yeast telomerase rna dimerization
naadp mobilizes calcium from the endoplasmic reticular ca2+ store in t-lymphocytes
sequential recruitment of pcaf and brg1 contributes to myogenin activation in 12-o-tetradecanoylphorbol-13-acetate-induced early differentiation of rhabdomyosarcoma..
arabidopsis vtc2 encodes a gdp-l-galactose phosphorylase, the last unknown enzyme in the smirnoff-wheeler pathway to ascorbic acid in plants
a novel binding site for the human insulin-like growth factor-ii (igf-ii)/mannose 6-phosphate receptor on igf-ii
internalized antibodies to the a domain of app reduce neuronal a and protect against synaptic alterations
structural rearrangements between portal protein subunits are essential for viral dna translocation
src utilizes cas to block gap junctional communication mediated by connexin43
raet1e2, a soluble isoform of the ul16-binding protein raet1e produced by tumor cells, inhibits nkg2d-mediated nk cytotoxicity
substrate-mediated regulation of cullin neddylation
disruption of the aspartate to heme ester linkage in human myeloperoxidase
o-fucosylation of thrombospondin type 1 repeats in adamts-like-1/punctin-1 regulates secretion
arabidopsis thaliana squalene epoxidase 1 is essential for root and seed development
o-fucosylation is required for adamts13 secretion
negative elongation factor nelf represses human immunodeficiency virus transcription by pausing the rna polymerase ii complex
adam-15/metargidin mediates homotypic aggregation of human t lymphocytes and heterotypic interactions of t lymphocytes with intestinal epithelial cells
prostaglandin e2-ep4 receptor promotes endothelial cell migration via erk activation and angiogenesis in vivo
ribosomal protein rps2 is hypomethylated in prmt3-deficient mice
insights into how cub domains can exert specific functions while sharing a common fold
photooxidation generates biologically active phospholipids that induce heme oxygenase-1 in skin cells
site-specific mutations in hiv-1 gp41 reveal a correlation between hiv-1-mediated bystander apoptosis and fusion/hemifusion
the microneme proteins etmic4 and etmic5 of eimeria tenella form a novel, ultra-high molecular mass protein complex that binds target host cells
hypotonic activation of short clc3 isoform is modulated by direct interaction between its cytosolic c-terminal tail and subcortical actin filaments
regulation of snf1 protein kinase in response to environmental stress
defining paxilline biosynthesis in penicillium paxilli
p53r2-dependent ribonucleotide reduction provides deoxyribonucleotides in quiescent human fibroblasts in the absence of induced dna damage
identification of a dominant negative functional domain on dapk-1 that degrades dapk-1 protein and stimulates tnfr-1-mediated apoptosis
closed-state cross-linking of adjacent 1 subunits in 11 gabaa receptors via introduced 6‘ cysteines
arsd residues cys12, cys13, and cys18 form an as(iii)-binding site required for arsenic metallochaperone activity
trka receptor “hot spots“ for binding of nt-3 as a heterologous ligand
specific grb2-mediated interactions regulate clathrin-dependent endocytosis of the cmet-tyrosine kinase
phosphatidylethanolamine, a limiting factor of autophagy in yeast strains bearing a defect in the carboxypeptidase y pathway of vacuolar targeting
fukutin-related protein associates with the sarcolemmal dystrophin-glycoprotein complex
involvement of dihydroceramide desaturase in cell cycle progression in human neuroblastoma cells
interaction between familial amyotrophic lateral sclerosis (als)-linked sod1 mutants and the dynein complex
unique peroxidase reaction mechanism in prostaglandin endoperoxide h synthase-
the hyaluronan receptors cd44 and rhamm (cd168) form complexes with erk1,2 that sustain high basal motility in breast cancer cells
binding of phosphoinositide-specific phospholipase c- (plc-) to phospholipid membranes
ehd1 and eps15 interact with phosphatidylinositols via their eps15 homology domains
a bax/bak-independent mechanism of cytochrome c release
activation of the kinase activity of atm by retinoic acid is required for creb-dependent differentiation of neuroblastoma cells
calreticulin affects fibronectin-based cell-substratum adhesion via the regulation of c-src activity
structural and functional analysis of 29 p16.7c dimerization mutants
the major secreted cathepsin l1 protease of the liver fluke, fasciola hepatica
tau aggregation and toxicity in a cell culture model of tauopathy
noncovalent binding of small ubiquitin-related modifier (sumo) protease to sumo is necessary for enzymatic activities and cell growth
glyoxylate and pyruvate are antagonistic effectors of the escherichia coli iclr transcriptional regulator
selective inhibition of the collagenase activity of cathepsin k
hypoxia-inducible factor-1, a key factor in the keratinocyte response to uvb exposure
overlapping roles of the methylated dna-binding protein mbd1 and polycomb group proteins in transcriptional repression of hoxa genes and heterochromatin foci format..
regulation of copper homeostasis by micro-rna in arabidopsis
molecular determinants for the selective inhibition of cyclooxygenase-2 by lumiracoxib
escherichia coli muts tetramerization domain structure reveals that stable dimers but not tetramers are essential for dna mismatch repair in vivo
structural basis of na+ activation mimicry in murine thrombin
molecular basis for chloronium-mediated meroterpene cyclization
different modes of binding of mono- and biaromatic effectors to the transcriptional regulator ttgv
crystal structures and site-directed mutagenesis of a mycothiol-dependent enzyme reveal a novel folding and molecular basis for mycothiol-mediated maleylpyruvate is..
inactivation of the phosphoinositide phosphatases sac1p and inp54p leads to accumulation of phosphatidylinositol 4,5-bisphosphate on vacuole membranes and vacuolar ..
exoribonuclease r in pseudomonas syringae is essential for growth at low temperature and plays a novel role in the 3‘ end processing of 16 and 5 s ribosomal rna
identification of novel wilms‘ tumor suppressor gene target genes implicated in kidney development
unique dimeric structure of bnip3 transmembrane domain suggests membrane permeabilization as a cell death trigger
nadph oxidase nox5-s mediates acid-induced cyclooxygenase-2 expression via activation of nf-bin barrett‘s esophageal adenocarcinoma cells
hoxa10 activates transcription of the gene encoding mitogen-activated protein kinase phosphatase 2 (mkp2) in myeloid cells
the role of complex formation between the escherichia coli hydrogenase accessory factors hypb and slyd
in cultured astrocytes, p53 and mdm2 do not alter hypoxia-inducible factor-1 function regardless of the presence of dna damage
picornavirus genome replication
the mobile thylakoid phosphoprotein tsp9 interacts with the light-harvesting complex ii and the peripheries of both photosystems
functional linkage between noxa and bim in mitochondrial apoptotic events
regulation of adamts9 secretion and enzymatic activity by its propeptide
a conserved sequence immediately n-terminal to the bateman domains in amp-activated protein kinase subunits is required for the interaction with the subunits
the membrane-proximal portion of cd3 associates with the serine/threonine kinase grk2
caspase inhibition sensitizes inhibitor of nf-b kinase -deficient fibroblasts to caspase-independent cell death via the generation of reactive oxygen species
receptor-mediated endocytosis involves tyrosine phosphorylation of cortactin
the decorin sequence syiriadtnit binds collagen type i
redox silencing of copper in metal-linked neurodegenerative disorders
transcriptional silencing of nonsense codon-containing immunoglobulin µ genes requires translation of its mrna
role of tlr4 tyrosine phosphorylation in signal transduction and endotoxin tolerance
the interleukin-22/stat3 pathway potentiates expression of inducible nitric-oxide synthase in human colon carcinoma cells
trypanosoma brucei encodes a bifunctional capping enzyme essential for cap 4 formation on the spliced leader rna
the role of a single-stranded nucleotide loop in transcriptional regulation of the human sod2 gene
up-regulation of the cell integrity pathway in saccharomyces cerevisiae suppresses temperature sensitivity of the pgs1 mutant
curcumin prevents tumor-induced t cell apoptosis through stat-5a-mediated bcl-2 induction
multisite phosphorylation of nuclear interaction partner of alk (nipa) at g2/m involves cyclin b1/cdk1
foxp3 enhances hiv-1 gene expression by modulating nfb occupancy at the long terminal repeat in human t cells
lumazine synthase from candida albicans as an anti-fungal target enzyme
crystal structure of uridine-diphospho-n-acetylglucosamine pyrophosphorylase from candida albicans and catalytic reaction mechanism
protein kinase a-regulated nucleocytoplasmic shuttling of id1 during angiogenesis
identification, molecular cloning, and characterization of the sixth subunit of human transcription factor tfiiic
reaction mechanism of glutathione synthetase from arabidopsis thaliana
carma1 coiled-coil domain is involved in the oligomerization and subcellular localization of carma1 and is required for t cell receptor-induced nf-b activation
regulation of type ii collagen expression by histone deacetylase in articular chondrocytes
rhizobium etli ce3 bacteroid lipopolysaccharides are structurally similar but not identical to those produced by cultured ce3 bacteria
inhibiting proteasomal degradation of microsomal triglyceride transfer protein prevents ccl4-induced steatosis
nucleoplasmic calcium is required for cell proliferation
critical role for transcription coactivator peroxisome proliferator-activated receptor (ppar)-binding protein/trap220 in liver regeneration and ppar ligand-induced ..
resolution of the nuclear localization mechanism of glycogen synthase kinase-
solution structure of human secretory component and implications for biological function
enhancing the latent nucleotide triphosphate flexibility of the glucose-1-phosphate thymidylyltransferase rmla
high resolution footprinting of the hepatitis c virus polymerase ns5b in complex with rna
expression and mechanism of spleen tyrosine kinase activation by angiotensin ii and its implication in protein synthesis in rat vascular smooth muscle cells
the retinoblastoma protein is an essential mediator of osteogenesis that links the p204 protein to the cbfa1 transcription factor thereby increasing its activity
identification of a hoxa10 activation domain necessary for transcription of the gene encoding 3 integrin during myeloid differentiation
phosphorylation of p68 rna helicase plays a role in platelet-derived growth factor-induced cell proliferation by up-regulating cyclin d1 and c-myc expression
rbck1 negatively regulates tumor necrosis factor- and interleukin-1-triggered nf-b activation by targeting tab2/3 for degradation
role of the transcription factor atf4 in the anabolic actions of insulin and the anti-anabolic actions of glucocorticoids
nucleoside phosphorylation by phosphate minerals
down-regulation of polysialic acid is required for efficient myelin formation
crystal structure of the cysteine-rich domain of scavenger receptor marco reveals the presence of a basic and an acidic cluster that both contribute to ligand recog..
genetic evidence supporting caveolae microdomain regulation of calcium entry in endothelial cells
the rab5 activator als2/alsin acts as a novel rac1 effector through rac1-activated endocytosis
h2s, endoplasmic reticulum stress, and apoptosis of insulin-secreting beta cells
munc18c interaction with syntaxin 4 monomers and snare complex intermediates in glut4 vesicle trafficking
-globin active chromatin hub formation in differentiating erythroid cells and in p45 nf-e2 knock-out mice
regulation of protein phosphatase inhibitor-1 by cyclin-dependent kinase 5
gsk-3 acts upstream of fyn kinase in regulation of nuclear export and degradation of nf-e2 related factor 2
ataxia telangiectasia mutated (atm) signaling network is modulated by a novel poly(adp-ribose)-dependent pathway in the early response to dna-damaging agents
the phosphorylation state of glur1 subunits determines the susceptibility of ampa receptors to calpain cleavage
neogenin-rgma signaling at the growth cone is bone morphogenetic protein-independent and involves rhoa, rock, and pkc
xb130, a novel adaptor protein for signal transduction
post-translational methylation of high mobility group box 1 (hmgb1) causes its cytoplasmic localization in neutrophils
biochemical and functional characterization of orai proteins
ligand binding and calcium influx induce distinct ectodomain/-secretase-processing pathways of ephb2 receptor
structure-function relationships of the viral rna-dependent rna polymerase
expression of allosteric linkage between the sodium ion binding site and exosite i of thrombin during prothrombin activation
rna binding-independent dimerization of adenosine deaminases acting on rna and dominant negative effects of nonfunctional subunits on dimer functions
-dystroglycan as a target for mmp-9, in response to enhanced neuronal activity
mechanisms for picrotoxinin and picrotin blocks of 2 homomeric glycine receptors
remote control of gene expression
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