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distinct targeting and fusion functions of the px and snare domains of yeast vacuolar vam7p
disabled-2 is an epithelial surface positioning gene
crystal structure of the bcl-xl-beclin 1 peptide complex
crystal structure of stal, a glycopeptide antibiotic sulfotransferase from streptomyces toyocaensis
identification and characterization of a new class of trafficking motifs for controlling clathrin-independent internalization and recycling
opposing actions of endocannabinoids on cholangiocarcinoma growth
alcohol/cholecystokinin-evoked pancreatic acinar basolateral exocytosis is mediated by protein kinase c phosphorylation of munc18c
intracellular localization of type iii-delivered pseudomonas exos with endosome vesicles
isolation, cloning, and characterization of a novel phosphomannan-binding lectin from porcine serum
determining the molecular basis for the ph-dependent interaction between the link module of human tsg-6 and hyaluronan
structural basis for the conformational integrity of the arabidopsis thaliana hy5 leucine zipper homodimer
open and closed structures of the udp-glucose pyrophosphorylase from leishmania major
a matrix metalloproteinase-9 activation cascade by hepatic stellate cells in trans-differentiation in the three-dimensional extracellular matrix
structural and functional consequences of coenzyme binding to the inactive asian variant of mitochondrial aldehyde dehydrogenase
lack of schnurri-2 expression associates with reduced bone remodeling and osteopenia
functional characterization of cis and trans activity of the flavivirus ns2b-ns3 protease
cadherin conformations associated with dimerization and adhesion
change in substrate specificity of cytotoxic necrotizing factor unmasks proteasome-independent down-regulation of constitutively active rhoa
activation of camkiic is a common intermediate of diverse death stimuli-induced heart muscle cell apoptosis
formation of hyaluronan- and versican-rich pericellular matrix by prostate cancer cells promotes cell motility
protein kinase ck2, cystic fibrosis transmembrane conductance regulator, and the f508 mutation
functional and therapeutic analysis of hepatitis c virus ns3·4a protease control of antiviral immune defense
a pentatricopeptide repeat protein is required for rna processing of clpp pre-mrna in moss chloroplasts
crystal structure of the serine protease domain of prophenoloxidase activating factor-i
golgi gdp-fucose transporter-deficient mice mimic congenital disorder of glycosylation iic/leukocyte adhesion deficiency ii
bone morphogenetic protein 2 activates smad6 gene transcription through bone-specific transcription factor runx2
cytosolic hydroxymethyldihydropterin pyrophosphokinase/dihydropteroate synthase from arabidopsis thaliana
roles of hemoglobin allostery in hypoxia-induced metabolic alterations in erythrocytes
deactivation and proton transfer in light-induced metarhodopsin ii/metarhodopsin iii conversion
thermodynamic analysis of h1 nuclear import
deafness and stria vascularis defects in s1p2 receptor-null mice
epidermal growth factor directs sex-specific steroid signaling through src activation
the alloantigenic sites of 345(iv) collagen
crystal structure of the rna polymerase domain of the west nile virus non-structural protein 5
phosphorylation of tyrosine 801 of vascular endothelial growth factor receptor-2 is necessary for akt-dependent endothelial nitric-oxide synthase activation and nit..
dna sequences from arabidopsis, which encode protein kinases and function as upstream regulators of snf1 in yeast
non-heme induction of heme oxygenase-1 does not alter cellular iron metabolism
non-apoptotic phosphatidylserine externalization induced by engagement of glycosylphosphatidylinositol-anchored proteins
targeted gene deletion of leishmania major udp-galactopyranose mutase leads to attenuated virulence
neural expression of g protein-coupled receptors gpr3, gpr6, and gpr12 up-regulates cyclic amp levels and promotes neurite outgrowth
p53-dependent aph-1 and pen-2 anti-apoptotic phenotype requires the integrity of the -secretase complex but is independent of its activity
identification of a glycosaminoglycan binding region of the alpha c protein that mediates entry of group b streptococci into host cells
the crystal structure of trex1 explains the 3‘ nucleotide specificity and reveals a polyproline ii helix for protein partnering
allelic variation in the depressaria pastinacella cyp6ab3 protein enhances metabolism of plant allelochemicals by altering a proximal surface residue and potential ..
sox9 regulates prostaglandin d synthase gene transcription in vivo to ensure testis development
action spectrum of drosophila cryptochrome
reversible monoubiquitination regulates the parkinson disease-associated ubiquitin hydrolase uch-l1
use of a camp bret sensor to characterize a novel regulation of camp by the sphingosine 1-phosphate/g13 pathway
identification of a pool of non-pumping na/k-atpase
participation of the fingers subdomain of escherichia coli dna polymerase i in the strand displacement synthesis of dna
loading of the nonhomologous end joining factor, ku, on protein-occluded dna ends
srg3 interacts directly with the major components of the swi/snf chromatin remodeling complex and protects them from proteasomal degradation
crystal structure of the heme-isdc complex, the central conduit of the isd iron/heme uptake system in staphylococcus aureus
the nicastrin-like protein nicalin regulates assembly and stability of the nicalin-nodal modulator (nomo) membrane protein complex
interaction of potassium cyanide with the [ni-4fe-5s] active site cluster of co dehydrogenase from carboxydothermus hydrogenoformans
cleavage and oligomerization of gliomedin, a transmembrane collagen required for node of ranvier formation
transforming growth factor- receptor type i-dependent fibrogenic gene program is mediated via activation of smad1 and erk1/2 pathways
dynamic regulation of cystic fibrosis transmembrane conductance regulator by competitive interactions of molecular adaptors
splice variants of the human zinc transporter znt5 (slc30a5) are differentially localized and regulated by zinc through transcription and mrna stability
characterization of a novel tripartite nuclear localization sequence in the egfr family
structure and function of the c-myc dna-unwinding element-binding protein due-b
structural insights into corepressor recognition by antagonist-bound estrogen receptors
structure of a four-way bridged parb-dna complex provides insight into p1 segrosome assembly
extension of human cell lifespan by nicotinamide phosphoribosyltransferase
a novel protein-processing domain in gli2 and gli3 differentially blocks complete protein degradation by the proteasome
yeast cells lacking the mitochondrial gene encoding the atp synthase subunit 6 exhibit a selective loss of complex iv and unusual mitochondrial morphology
knockdown of dna ligase iv/xrcc4 by rna interference inhibits herpes simplex virus type i dna replication
hypoxia-inducible factor 1 (hif-1)-mediated hypoxia increases bace1 expression and -amyloid generation
a novel promoter element containing multiple overlapping xenobiotic and hypoxia response elements mediates induction of cytochrome p4502s1 by both dioxin and hypoxia
the factor h variant associated with age-related macular degeneration (his-384) and the non-disease-associated form bind differentially to c-reactive protein, fibro..
hetero-oligomerization with mdmx rescues the ubiquitin/nedd8 ligase activity of ring finger mutants of mdm2
lesion bypass activity of dna polymerase a from the extremely radioresistant organism deinococcus radiodurans
late assembly steps and dynamics of the cyanobacterial photosystem i
alterations of ceramide/sphingosine 1-phosphate rheostat involved in the regulation of resistance to imatinib-induced apoptosis in k562 human chronic myeloid leukem..
characterization of p43(arf), a derivative of the p43 component of multiaminoacyl-trna synthetase complex released during apoptosis
p1 partition complex assembly involves several modes of protein-dna recognition
evidence for 1,25-dihydroxyvitamin d3-independent transactivation by the vitamin d receptor
an active nuclear retention signal in the glucocorticoid receptor functions as a strong inducer of transcriptional activation
the selenium-rich c-terminal domain of mouse selenoprotein p is necessary for the supply of selenium to brain and testis but not for the maintenance of whole body s..
mannose foraging by bacteroides thetaiotaomicron
transcriptional activation by cprk1 is regulated by protein structural changes induced by effector binding and redox state
arginine vasopressin-mediated cardiac differentiation
sialylated core 1 o-glycans influence the sorting of pmel17/gp100 and determine its capacity to form fibrils
the cytokine, granulocyte-macrophage colony-stimulating factor (gm-csf), can deliver bcl-xl as an extracellular fusion protein to protect cells from apoptosis and r..
transition of escherichia coli from aerobic to micro-aerobic conditions involves fast and slow reacting regulatory components
calcium influx and mitochondrial alterations at synapses exposed to snake neurotoxins or their phospholipid hydrolysis products
phosphorylation of -catenin by akt promotes -catenin transcriptional activity
conserved structural and functional properties of d-domain containing redox-active and -inactive protein disulfide isomerase-related protein chaperones
the dynlt3 light chain directly links cytoplasmic dynein to a spindle checkpoint protein, bub3
restoration of liver mass after injury requires proliferative and not embryonic transcriptional patterns
thioredoxin suppresses parkin-associated endothelin receptor-like receptor-induced neurotoxicity and extends longevity in drosophila
ability of polymerase and t7 dna polymerase to bypass bulge structures
cabin1 represses mef2 transcriptional activity by association with a methyltransferase, suv39h1
specific features of the prion protein transmembrane domain regulate nascent chain orientation
length-dependent binding of human xlf to dna and stimulation of xrcc4·dna ligase iv activity
the requirement of the glutamic acid residue at the third position from the carboxyl termini of the laminin chains in integrin binding by laminins
role of crkii in fc receptor-mediated phagocytosis
preferential phosphorylation of focal adhesion kinase tyrosine 861 is critical for mediating an anti-apoptotic response to hyperosmotic stress
flavin binding to the high affinity riboflavin transporter ribu
akt attenuation of the serine protease activity of htra2/omi through phosphorylation of serine 212
a substrate specificity-determining unit of three lin12-notch repeat modules is formed in trans within the pappalysin-1 dimer and requires a sequence stretch c-term..
the reductase that catalyzes mycolic motif synthesis is required for efficient attachment of mycolic acids to arabinogalactan
polyamine-mediated apoptosis of alveolar macrophages during pneumocystis pneumonia
primary structure and carbohydrate binding specificity of a potent anti-hiv lectin isolated from the filamentous cyanobacterium oscillatoria agardhii
physicochemical and biological analysis of synthetic bacterial lipopeptides
differential modulation of 3t3-l1 adipogenesis mediated by 11-hydroxysteroid dehydrogenase-1 levels
the rpb7 orthologue e‘ is required for transcriptional activity of a reconstituted archaeal core enzyme at low temperatures and stimulates open complex formation
ssb protein limits recor binding onto single-stranded dna
p62 accumulates and enhances aggregate formation in model systems of familial amyotrophic lateral sclerosis
conformational fluctuations coupled to the thiol-disulfide transfer between thioredoxin and arsenate reductase in bacillus subtilis
an essential oligomannosidic glycan chain in the catalytic domain of autotaxin, a secreted lysophospholipase-d
regulation of human lzip expression by nf-b and its involvement in monocyte cell migration induced by lkn-1
identification of an adamts-4 cleavage motif using phage display leads to the development of fluorogenic peptide substrates and reveals matrilin-3 as a novel substr..
basic fibroblast growth factor stimulates matrix metalloproteinase-13 via the molecular cross-talk between the mitogen-activated protein kinases and protein kinase ..
gemin2 plays an important role in stabilizing the survival of motor neuron complex
escherichia coli di-iron ytfe protein is necessary for the repair of stress-damaged iron-sulfur clusters
the conserved cph domains of cul7 and parc are protein-protein interaction modules that bind the tetramerization domain of p53
light chain 1 of microtubule-associated protein 1b can negatively regulate the action of pes1
the nh2-terminal domain of the chloroplast grpe homolog cge1 is required for dimerization and cochaperone function in vivo
-arrestin and mdm2 mediate igf-1 receptor-stimulated erk activation and cell cycle progression
topology and active site of plsy
cartilage oligomeric matrix protein associates with granulin-epithelin precursor (gep) and potentiates gep-stimulated chondrocyte proliferation
an electrostatic/hydrogen bond switch as the basis for the specific interaction of phosphatidic acid with proteins
competition between ski and creb-binding protein for binding to smad proteins in transforming growth factor- signaling
stabilizing effect of zn2+ in native bovine rhodopsin
a novel endoglycoceramidase hydrolyzes oligogalactosylceramides to produce galactooligosaccharides and ceramides
acute -adrenergic overload produces myocyte damage through calcium leakage from the ryanodine receptor 2 but spares cardiac stem cells
in vitro comparative kinetic analysis of the chloroplast toc gtpases
allosteric activation by dimerization of the pknd receptor ser/thr protein kinase from mycobacterium tuberculosis
conformation-sensitive antibodies against alzheimer amyloid- by immunization with a thioredoxin-constrained b-cell epitope peptide
the molecular basis of glyphosate resistance by an optimized microbial acetyltransferase
stim1 knockdown reveals that store-operated ca2+ channels located close to sarco/endoplasmic ca2+ atpases (serca) pumps silently refill the endoplasmic reticulum
altered tethering of the sspb adaptor to the clpxp protease causes changes in substrate delivery
molecular framework for the activation of rna-dependent protein kinase
different mechanisms are involved in the transcriptional activation by yeast heat shock transcription factor through two different types of heat shock elements
protein phosphatases 2a and 1 interact with occludin and negatively regulate the assembly of tight junctions in the caco-2 cell monolayer
traffic to the malaria parasite food vacuole
rgk small gtp-binding proteins interact with the nucleotide kinase domain of ca2+-channel -subunits via an uncommon effector binding domain
mitotic phosphorylation of dynamin-related gtpase drp1 participates in mitochondrial fission
integration of the activation of the human hyaluronan synthase 2 gene promoter by common cofactors of the transcription factors retinoic acid receptor and nuclear f..
increased internalization of p120-uncoupled e-cadherin and a requirement for a dileucine motif in the cytoplasmic domain for endocytosis of the protein
activation of acid sphingomyelinase by protein kinase c-mediated phosphorylation
structural and functional characterization of partner switching regulating the environmental stress response in bacillus subtilis
crystal structure and cell surface anchorage sites of laminin 1lg4-5
the reovirus 1 aspartic acid sandwich
a oligomers induce neuronal oxidative stress through an n-methyl-d-aspartate receptor-dependent mechanism that is blocked by the alzheimer drug memantine
an interferon 2 mutant optimized by phage display for ifnar1 binding confers specifically enhanced antitumor activities
modulation of the interferon antiviral response by the tbk1/ikki adaptor protein tank
a comparative analysis of the fibulin protein family
calcineurin potentiates the activation of procaspase-3 by accelerating its proteolytic maturation
regulation of death-associated protein kinase
differential modulation of nods signaling pathways by fatty acids in human colonic epithelial hct116 cells
post-induction, stimulus-specific regulation of tumor necrosis factor mrna expression
phosphorylation of threonine residue 276 is required for acute regulation of serotonin transporter by cyclic gmp
a sequence motif in the simian virus 40 (sv40) early core promoter affects alternative splicing of transcribed mrna
murine cxcr1 is a functional receptor for gcp-2/cxcl6 and interleukin-8/cxcl8
virion-associated uracil dna glycosylase-2 and apurinic/apyrimidinic endonuclease are involved in the degradation of apobec3g-edited nascent hiv-1 dna
function, activity, and membrane targeting of cytosolic phospholipase a2 in mouse lung fibroblasts
protein kinase a suppresses sterol regulatory element-binding protein-1c expression via phosphorylation of liver x receptor in the liver
structures of activated fructose-1,6-bisphosphatase from escherichia coli
cdc6 atpase activity regulates orc·cdc6 stability and the selection of specific dna sequences as origins of dna replication
madd/denn splice variant of the ig20 gene is a negative regulator of caspase-8 activation
antiproliferative autoantigen cda1 transcriptionally up-regulates p21waf1/cip1 by activating p53 and mek/erk1/2 mapk pathways
estrogen receptor and the activating protein-1 complex cooperate during insulin-like growth factor-i-induced transcriptional activation of the ps2/tff1 gene
manduca sexta hemolymph proteinase 21 activates prophenoloxidase-activating proteinase 3 in an insect innate immune response proteinase cascade
hypoxia-inducible factor 2 regulates expression of the mitochondrial aconitase chaperone protein frataxin
a role of lipophilic peptidoglycan-related molecules in induction of nod1-mediated immune responses
regulation of a transcript encoding the proline-rich membrane anchor of globular muscle acetylcholinesterase
block of nuclear receptor ubiquitination
actin-binding protein -actinin-1 interacts with the metabotropic glutamate receptor type 5b and modulates the cell surface expression and function of the receptor
na/k-atpase 1 subunit expression is required for blastocyst formation and normal assembly of trophectoderm tight junction-associated proteins
regulation of the voltage-gated k+ channels kcnq2/3 and kcnq3/5 by ubiquitination
heptad repeats regulate protein phosphatase 2a recruitment to i-b kinase /nf-b essential modulator and are targeted by human t-lymphotropic virus type 1 tax
identification of an in vivo inhibitor of bacillus anthracis spore germination
granzyme k directly processes bid to release cytochrome c and endonuclease g leading to mitochondria-dependent cell death
functionally and spatially distinct modes of munc18-syntaxin 1 interaction
nm23-h1 tumor suppressor physically interacts with serine-threonine kinase receptor-associated protein, a transforming growth factor- (tgf-) receptor-interacting pr..
a tomato endo--1,4-glucanase, slcel9c1, represents a distinct subclass with a new family of carbohydrate binding modules (cbm49)
sphingosine kinase type 2 activation by erk-mediated phosphorylation
the werner syndrome helicase is a cofactor for hiv-1 long terminal repeat transactivation and retroviral replication
identification of anesthetic binding sites on human serum albumin using a novel etomidate photolabel
the generation of the oxidized form of creatine kinase is a negative regulation on muscle creatine kinase
inhibition of gsk3 promotes replication and survival of pancreatic beta cells
pro-apoptotic activity of novel isatin-schiff base copper(ii) complexes depends on oxidative stress induction and organelle-selective damage
zebrafish slc5a12 encodes an electroneutral sodium monocarboxylate transporter (smctn)
the calcium-binding c-terminal domain of escherichia coli -hemolysin is a major determinant in the surface-active properties of the protein
p21-activated kinase 1 is activated through the mammalian target of rapamycin/p70 s6 kinase pathway and regulates the replication of hepatitis c virus in human hepa..
endothelial cell protein c receptor acts as a cellular receptor for factor viia on endothelium
expression, purification, characterization, and in vivo targeting of trypanosome ctp synthetase for treatment of african sleeping sickness
the helicobacter pylori amidotransferase gatcab is equally efficient in glutamine-dependent transamidation of asp-trnaasn and glu-trnagln
role of phosphatidylinositol 3-kinases in chemotaxis in dictyostelium
the high reactivity of peroxiredoxin 2 with h2o2 is not reflected in its reaction with other oxidants and thiol reagents
a novel branched-chain amino acid metabolon
the two active sites in human branched-chain -keto acid dehydrogenase operate independently without an obligatory alternating-site mechanism
tests of the extension and deadbolt models of integrin activation
the n-terminal extensions of deinococcus radiodurans dps-1 mediate dna major groove interactions as well as assembly of the dodecamer
hsp40 interacts directly with the native state of the yeast prion protein ure2 and inhibits formation of amyloid-like fibrils
novel triphosphate phosphohydrolase activity of clostridium thermocellum ttm, a member of the triphosphate tunnel metalloenzyme superfamily
processing of dna for nonhomologous end-joining is controlled by kinase activity and xrcc4/ligase iv
selenoprotein h is a nucleolar thioredoxin-like protein with a unique expression pattern
the notch regulator maml1 interacts with p53 and functions as a coactivator
regulated intramembrane proteolysis of the interleukin-1 receptor ii by -, -, and -secretase
choline redistribution during adaptation to choline deprivation
interaction between sterol regulatory element-binding proteins and liver receptor homolog-1 reciprocally suppresses their transcriptional activities
common structural requirements for heptahelical domain function in class a and class c g protein-coupled receptors
pawp, a sperm-specific ww domain-binding protein, promotes meiotic resumption and pronuclear development during fertilization
relocalization of stim1 for activation of store-operated ca2+ entry is determined by the depletion of subplasma membrane endoplasmic reticulum ca2+ store
identification of nascent chain interaction sites on trigger factor
role of dna methylation in stable gene repression
highly tolerated amino acid substitutions increase the fidelity of escherichia coli dna polymerase i
a role for molecular chaperone hsc70 in reovirus outer capsid disassembly
crystal structure of helicobacter pylori formamidase amif reveals a cysteine-glutamate-lysine catalytic triad
the “jaws“ of the tau-microtubule interaction
a structural model of the cytochrome c reductase/oxidase supercomplex from yeast mitochondria
inhibition of the extracellular signal-regulated kinase/mitogen-activated protein kinase pathway decreases dna methylation in colon cancer cells
post-endocytic sorting of calcitonin receptor-like receptor and receptor activity-modifying protein 1
3-phosphoinositide-dependent pdk1 negatively regulates transforming growth factor--induced signaling in a kinase-dependent manner through physical interaction with ..
apolipoprotein e receptor-2 (apoer2) mediates selenium uptake from selenoprotein p by the mouse testis
high resolution structure of deinococcus bacteriophytochrome yields new insights into phytochrome architecture and evolution
relative sensitivity of parkin and other cysteine-containing enzymes to stress-induced solubility alterations
kinetic characterization of the disulfide bond-forming enzyme dsbb
process elongation of oligodendrocytes is promoted by the kelch-related protein mrp2/klhl1
selective substrate supply in the regulation of yeast de novo sphingolipid synthesis
the reversion-inducing cysteine-rich protein with kazal motifs (reck) interacts with membrane type 1 matrix metalloproteinase and cd13/aminopeptidase n and modulate..
ring structure of the escherichia coli dna-binding protein rdgc associated with recombination and replication fork repair
vps75, a new yeast member of the nap histone chaperone family
microrna mir-133 represses herg k+ channel expression contributing to qt prolongation in diabetic hearts
yeast ribosomal/cytochrome c set domain methyltransferase subfamily
bisphosphonates as inhibitors of trypanosoma cruzi hexokinase
a42 overproduction associated with structural changes in the catalytic pore of -secretase
the c-type lectin receptors clec-2 and dectin-1, but not dc-sign, signal via a novel yxxl-dependent signaling cascade
egln3 prolyl hydroxylase regulates skeletal muscle differentiation and myogenin protein stability
segments crucial for membrane translocation and pore-forming activity of bordetella adenylate cyclase toxin
cytochrome c oxidase activity and oxygen tolerance
nucleolin regulates gene expression in cd34-positive hematopoietic cells
ceramide recruits and activates protein kinase c (pkc) within structured membrane microdomains
thyroid hormone response element organization dictates the composition of active receptor
glutaredoxin regulates nuclear factor -b and intercellular adhesion molecule in müller cells
a rapid transient increase in hyaluronan synthase-2 mrna initiates secretion of hyaluronan by corneal keratocytes in response to transforming growth factor
the elastin receptor complex transduces signals through the catalytic activity of its neu-1 subunit
influence of the redox potential of the primary quinone electron acceptor on photoinhibition in photosystem ii
n-myc regulates focal adhesion kinase expression in human neuroblastoma
biochemical studies of klebsiella pneumoniae nifl reduction using reconstituted partial anaerobic respiratory chains of wolinella succinogenes
o-linked n-acetylglucosaminyltransferase inhibition prevents g2/m transition in xenopus laevis oocytes
a transcription-dependent micrococcal nuclease-resistant fragment of the urokinase-type plasminogen activator promoter interacts with the enhancer
evidence that inhibition of hemojuvelin shedding in response to iron is mediated through neogenin
the subunit csn6 of the cop9 signalosome is cleaved during apoptosis
jnk1 is required for the induction of mkp1 expression in macrophages during proliferation and lipopolysaccharide-dependent activation
modular organization of the sulfolobus solfataricus mini-chromosome maintenance protein
key role for ceramides in mediating insulin resistance in human muscle cells
2,3,7,8-tetrachlorodibenzo-p-dioxin induces premature activation of the klf2 regulon during thymocyte development
mechanisms that prevent template inactivation by hiv-1 reverse transcriptase rnase h cleavages
human mitochondrial ribosomal protein mrpl12 interacts directly with mitochondrial rna polymerase to modulate mitochondrial gene expression
brain-derived neurotrophic factor regulates the expression and synaptic delivery of-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor subunits in hippoca..
in vivo and in vitro analyses of single-amino acid variants of the salmonella enterica phosphotransacetylase enzyme provide insights into the function of its n-term..
helix-helix interactions between homo- and heterodimeric -carboxyglutamate-containing conantokin peptides and their derivatives
improved pharmacokinetics of recombinant bispecific antibody molecules by fusion to human serum albumin
regulated binding of adenomatous polyposis coli protein to actin
signaling through g13 switch region i is essential for protease-activated receptor 1-mediated human platelet shape change, aggregation, and secretion
cholesterol binding does not predict activity of the steroidogenic acute regulatory protein, star
characterization of the cytochrome c oxidase assembly factor cox19 of saccharomyces cerevisiae
crystal structure of the third extracellular domain of cd5 reveals the fold of a group b scavenger cysteine-rich receptor domain
detergent-dependent kinetics of truncated plasmodium falciparumdihydroorotate dehydrogenase
molecular interactions of the gating modifier toxin protx-ii with nav1.
transient suppression of ligand-mediated activation of epidermal growth factor receptor by tumor necrosis factor- through the tak1-p38 signaling pathway
mammalian tumor suppressor int6 specifically targets hypoxia inducible factor 2 for degradation by hypoxia- and pvhl-independent regulation
inhibition of insulin secretion by betagranin, an n-terminal chromogranin a fragment
perturbation of endoplasmic reticulum homeostasis facilitates prion replication
disruption of the gdnf binding site in ncam dissociates ligand binding and homophilic cell adhesion
dna polymerase v allows bypass of toxic guanine oxidation products in vivo
the n-terminal flanking region of the trp2360-368 melanoma antigen determines proteasome activator pa28 requirement for epitope liberation
molecular basis of the isoform-specific ligand-binding affinity of inositol 1,4,5-trisphosphate receptors
molecular analysis of the role of tyrosine 224 in the active site of streptomyces coelicolor rppa, a bacterial type iii polyketide synthase
dynamics of the s1s2 glutamate binding domain of glur2 measured using 19f nmr spectroscopy
the role of arginine 310 in catalysis and substrate specificity in xanthine dehydrogenase from rhodobacter capsulatus
collagen xxvii is developmentally regulated and forms thin fibrillar structures distinct from those of classical vertebrate fibrillar collagens
determinants of 4-phorbol sensitivity in transmembrane domains 3 and 4 of the cation channel trpv4
interleukin-6 transcriptionally regulates prohibitin expression in intestinal epithelial cells
sumoylation of the transcriptional intermediary factor 1 (tif1), the co-repressor of the krab multifinger proteins, is required for its transcriptional activity and..
loss of secretory pathway fk506-binding proteins results in cold-sensitive lethality and associate extracellular matrix defects in the nematode caenorhabditis elegans
oct4 and sox2 directly regulate expression of another pluripotency transcription factor, zfp206, in embryonic stem cells
receptor-mediated endocytosis is not required for tumor necrosis factor-related apoptosis-inducing ligand (trail)-induced apoptosis
phosphorylation of parkin by the cyclin-dependent kinase 5 at the linker region modulates its ubiquitin-ligase activity and aggregation
poly(adp-ribose) polymerase 1 is inhibited by a histone h2a variant, macroh2a, and contributes to silencing of the inactive x chromosome
lysophosphatidic acid induces interleukin-13 (il-13) receptor 2 expression and inhibits il-13 signaling in primary human bronchial epithelial cells
ku70/80 modulates atm and atr signaling pathways in response to dna double strand breaks
a novel role for the glucocorticoid receptor in the regulation of monocyte chemoattractant protein-1 mrna stability
xaf1 mediates tumor necrosis factor--induced apoptosis and x-linked inhibitor of apoptosis cleavage by acting through the mitochondrial pathway
structure-based design, synthesis, evaluation, and crystal structures of transition state analogue inhibitors of inosine monophosphate cyclohydrolase
a novel photoreaction mechanism for the circadian blue light photoreceptor drosophila cryptochrome
a barley xyloglucan xyloglucosyl transferase covalently links xyloglucan, cellulosic substrates, and (1,3;1,4)--d-glucans
concerted nitric oxide formation and release from the simultaneous reactions of nitrite with deoxy- and oxyhemoglobin
phosphorylation of the endogenous thyrotropin-releasing hormone receptor in pituitary gh3 cells and pituitary tissue revealed by phosphosite-specific antibodies
pilz domain proteins bind cyclic diguanylate and regulate diverse processes in vibrio cholerae
green fluorescent protein impairs actin-myosin interactions by binding to the actin-binding site of myosin
focal adhesion kinase is negatively regulated by phosphorylation at tyrosine 407
the first extracellular loop of the saccharomyces cerevisiae g protein-coupled receptor ste2p undergoes a conformational change upon ligand binding
o-linked n-acetylglucosaminylation is involved in the ca2+ activation properties of rat skeletal muscle
the role of ampk and mtor in nutrient sensing in pancreatic -cells
prostaglandin e receptors
hepatocyte growth factor induces glucose uptake in 3t3-l1 adipocytes through a gab1/phosphatidylinositol 3-kinase/glut4 pathway
small molecule inhibitors of aggregation indicate that amyloid oligomerization and fibrillization pathways are independent and distinct
dna-binding activity of the erp57 c-terminal domain is related to a redox-dependent conformational change
a cell-permeable fusion toxin as a tool to study the consequences of actin-adp-ribosylation caused by the salmonella enterica virulence factor spvb in intact cells
cd30 activates both the canonical and alternative nf-b pathways in anaplastic large cell lymphoma cells
control of the glycolytic flux in saccharomyces cerevisiae grown at low temperature
igf-1-induced processing of the amyloid precursor protein family is mediated by different signaling pathways
a novel traf6 binding site in malt1 defines distinct mechanisms of nf-b activation by api2·malt1 fusions
salicylates trigger protein synthesis inhibition in a protein kinase r-like endoplasmic reticulum kinase-dependent manner
a network-based analysis of polyanion-binding proteins utilizing human protein arrays
response gene to complement 32, a novel regulator for transforming growth factor--induced smooth muscle differentiation of neural crest cells
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