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生物物理学杂志2007年第01期封面 购买


maize pollen coat xylanase facilitates pollen tube penetration into silk during sexual reproduction
mechanistic insights and functional determinants of the transport cycle of the ascorbic acid transporter svct
ccaat/enhancer-binding protein (c/ebp) is acetylated at multiple lysines
structural basis for the interaction of the myosin light chain mlc1p with the myosin v myo2p iq motifs
sordarin derivatives induce a novel conformation of the yeast ribosome translocation factor eef2
structure of human spindlin
spatial expression patterns and biochemical properties distinguish a second myo-inositol monophosphatase impa2 from impa1
micromolar intracellular hydrogen peroxide disrupts metabolism by damaging iron-sulfur enzymes
a novel neutrophil elastase inhibitor prevents elastase activation and surface cleavage of the epithelial sodium channel expressed in xenopus laevis oocytes
interruption of cryab-amyloid oligomer formation by hsp22
autoprocessing of helicobacter pylori -glutamyltranspeptidase leads to the formation of a threonine-threonine catalytic dyad
molecular cloning and functional characterization of psoralen synthase, the first committed monooxygenase of furanocoumarin biosynthesis
-catenin signaling pathway is crucial for bone morphogenetic protein 2 to induce new bone formation
contacts between extracellular loop two and transmembrane helix six determine basal activity of the thyroid-stimulating hormone receptor
the homeobox gene gax activates p21waf1/cip1 expression in vascular endothelial cells through direct interaction with upstream at-rich sequences
bcl2 is a downstream effector of miz-1 essential for blocking c-myc-induced apoptosis
conserved -helix acts as autoinhibitory sequence in amp-activated protein kinase subunits
reduction of carboxylic acids by nocardia aldehyde oxidoreductase requires a phosphopantetheinylated enzyme
-actinin-4 is required for normal podocyte adhesion
the platelet-derived growth factor receptor is destabilized by geldanamycins in cancer cells
mechanism of dun1 activation by rad53 phosphorylation in saccharomyces cerevisiae
iqgap1 stimulates actin assembly through the n-wasp-arp2/3 pathway
altered -3 substrate specificity of escherichia coli signal peptidase 1 mutants as revealed by screening a combinatorial peptide library
the t4 phage uvsw protein contains both dna unwinding and strand annealing activities
evidence of ball-and-chain transport of ferric enterobactin through fepa
the lim protein, limd1, regulates ap-1 activation through an interaction with traf6 to influence osteoclast development
binding of elongation factor eef1a2 to phosphatidylinositol 4-kinase stimulates lipid kinase activity and phosphatidylinositol 4-phosphate generation
crystal structure of the catalytic domain of matrix metalloproteinase-1 in complex with the inhibitory domain of tissue inhibitor of metalloproteinase-1
dissociation of nitric oxide from soluble guanylate cyclase and heme-nitric oxide/oxygen binding domain constructs
properties of the type b histone acetyltransferase hat
heparan sulfate analysis from diabetic rat glomeruli
purification and identification of proteins that bind to the hereditary persistence of fetal hemoglobin -198 mutation in the -globin gene promoter
tumor necrosis factor--stimulated cell proliferation is mediated through sphingosine kinase-dependent akt activation and cyclin d expression
an antisense transcript induced by wnt/-catenin signaling decreases e2f4
evidence for the pathophysiological role of endogenous methylarginines in regulation of endothelial no production and vascular function
phosphorylation of a threonine unique to the short c-terminal isoform of ii-spectrin links regulation of - spectrin interaction to neuritogenesis
lind/abin-3 is a novel lipopolysaccharide-inducible inhibitor of nf-b activation
microfibril-associated magp-2 stimulates elastic fiber assembly
wnt2 coordinates the commitment of mesoderm to hematopoietic, endothelial, and cardiac lineages in embryoid bodies
regulatory interplay between proton motive force, adp, phosphate, and subunit in bacterial atp synthase
acceptor specificity of the pasteurella hyaluronan and chondroitin synthases and production of chimeric glycosaminoglycans
urinary prostaglandin f2 is generated from the isoprostane pathway and not the cyclooxygenase in humans
evidence for two modes of development of acquired tumor necrosis factor-related apoptosis-inducing ligand resistance
r-ras controls axon specification upstream of glycogen synthase kinase-3 through integrin-linked kinase
conditional stimulation of type v and vi adenylyl cyclases by g protein subunits
a novel cdc42-interacting domain of the yeast polarity establishment protein bem
metabolic diapause in pancreatic -cells expressing a gain-of-function mutant of the forkhead protein foxo1
insulin controls subcellular localization and multisite phosphorylation of the phosphatidic acid phosphatase, lipin 1
human tim/timeless-interacting protein, tipin, is required for efficient progression of s phase and dna replication checkpoint
protein kinase c plays a non-redundant role in insulin secretion in pancreatic cells
platelet factor 4 (cxcl4) seals blood clots by altering the structure of fibrin
regulation of epha2 receptor endocytosis by ship2 lipid phosphatase via phosphatidylinositol 3-kinase-dependent rac1 activation
localization of the small cab-like proteins in photosystem ii
a ganglioside-induced toxic soluble a assembly
regulation of calpain activity in rat brain with altered ca2+ homeostasis
disulfide-dependent protein folding is linked to operation of the vitamin k cycle in the endoplasmic reticulum
the structure of a cyanobacterial bicarbonate transport protein, cmpa
apobec3f can inhibit the accumulation of hiv-1 reverse transcription products in the absence of hypermutation
calpain is required for the rapid, calcium-dependent repair of wounded plasma membrane
mucin 1 oncoprotein blocks hypoxia-inducible factor 1 activation in a survival response to hypoxia
foxd3 and grg4 physically interact to repress transcription and induce mesoderm in xenopus
novel n-3 fatty acid oxidation products activate nrf2 by destabilizing the association between keap1 and cullin3
loss of assembly of the main basement membrane collagen, type iv, but not fibril-forming collagens and embryonic death in collagen prolyl 4-hydroxylase i null mice
functional analysis of nicotine demethylase genes reveals insights into the evolution of modern tobacco
in vitro efficacy, resistance selection, and structural modeling studies implicate the malarial parasite apicoplast as the target of azithromycin
identification of mouse prp19p as a lipid droplet-associated protein and its possible involvement in the biogenesis of lipid droplets
protoporphyrin ix interacts with wild-type p53 protein in vitro and induces cell death of human colon cancer cells in a p53-dependent and -independent manner
regulation of polo-like kinase 1 by dna damage in mitosis
crystal structure of the -glutamyltranspeptidase precursor protein from escherichia coli
crystal structures of native and inactivated cis-3-chloroacrylic acid dehalogenase
expression and functional characterization of the cancer-related serine protease, human tissue kallikrein 14
nitric oxide modulates oxygen sensing by hypoxia-inducible factor 1-dependent induction of prolyl hydroxylase 2
visualization of aggregation of the rnq1 prion domain and cross-seeding interactions with sup35nm
a bacterial arginine-agmatine exchange transporter involved in extreme acid resistance
cell surface detachment of pregnancy-associated plasma protein-a requires the formation of intermolecular proteinase-inhibitor disulfide bonds and glycosaminoglycan..
glucose stimulates ca2+ influx and insulin secretion in 2-week-old -cells lacking atp-sensitive k+ channels
regulatory effects of mammalian target of rapamycin-activated pathways in type i and ii interferon signaling
the role of activating protein 1 in the transcriptional regulation of the human fcgr2b promoter mediated by the -343 g c polymorphism associated with systemic lupus..
puf protein-mediated deadenylation is catalyzed by ccr4p
a role for the conserved gaftga motif of aaa+ transcription activators in sensing promoter dna conformation
heparan sulfate proteoglycans (hspgs) modulate bmp2 osteogenic bioactivity in c2c12 cells
diatomic ligand discrimination by the heme oxygenases from neisseria meningitidis and pseudomonas aeruginosa
a unique loop extension in the serine protease domain of haptoglobin is essential for cd163 recognition of the haptoglobin-hemoglobin complex
insertion of anthrax protective antigen into liposomal membranes
atp6 homoplasmic mutations inhibit and destabilize the human f1f0-atp synthase without preventing enzyme assembly and oligomerization
execution of macrophage apoptosis by pe_pgrs33 of mycobacterium tuberculosis is mediated by toll-like receptor 2-dependent release of tumor necrosis factor-
supramolecular structure of the mitochondrial oxidative phosphorylation system
phospholipase action of platelet-activating factor acetylhydrolase, but not paraoxonase-1, on long fatty acyl chain phospholipid hydroperoxides
nitric oxide down-regulates polo-like kinase 1 through a proximal promoter cell cycle gene homology region
specific high affinity interactions of monomeric endotoxin·protein complexes with toll-like receptor 4 ectodomain
inverted factor access and slow reversion characterize swi/snf-altered nucleosome dimers
the c-terminal products of cellular prion protein processing, c1 and c2, exert distinct influence on p53-dependent staurosporine-induced caspase-3 activation
exercise-induced mitochondrial biogenesis begins before the increase in muscle pgc-1 expression
filamin-regulated f-actin assembly is essential for morphogenesis and controls phototaxis in dictyostelium
g12 specifically regulates cox-2 induction by sphingosine 1-phosphate
ethanol-induced modulation of hepatocellular extracellular signal-regulated kinase-1/2 activity via 4-hydroxynonenal
the atp binding cassette transporter atmrp5 modulates anion and calcium channel activities in arabidopsis guard cells
biochemical and structural characterization of the gem gtpase
n-linked oligosaccharides on the low density lipoprotein receptor homolog sorla/lr11 are modified with terminal galnac-4-so4 in kidney and brain
functional and phylogenetic properties of the pore-forming -barrel transporters of the omp85 family
fbxo11 promotes the neddylation of p53 and inhibits its transcriptional activity
phylogenetic divergence of cd47 interactions with human signal regulatory protein reveals locus of species specificity
studies of the biological properties of human -defensin 1
identification of a region of troponin i important in signaling cross-bridge-dependent activation of cardiac myofilaments
jam-c regulates tight junctions and integrin-mediated cell adhesion and migration
vmd2 promoter requires two proximal e-box sites for its activity in vivo and is regulated by the mitf-tfe family
cathepsin e deficiency induces a novel form of lysosomal storage disorder showing the accumulation of lysosomal membrane sialoglycoproteins and the elevation of lys..
disruption of interdomain interactions in the glutamate binding pocket affects differentially agonist affinity and efficacy of n-methyl-d-aspartate receptor activat..
structural determinants of human fancf protein that function in the assembly of a dna damage signaling complex
skp2 controls adipocyte proliferation during the development of obesity
ankyrin-g and 2-spectrin collaborate in biogenesis of lateral membrane of human bronchial epithelial cells
structural and functional studies of regb, a new member of a family of sequence-specific ribonucleases involved in mrna inactivation on the ribosome
cooperation of def6 with activated rac in regulating cell morphology
cytosolic and mitochondrial malic enzyme isoforms differentially control insulin secretion
coactivation of the n-terminal transactivation of mineralocorticoid receptor by ubc9
influence of charge distribution at the active site surface on the substrate specificity of human neutrophil protease 3 and elastase
apoa-i mimetic peptides with differing ability to inhibit atherosclerosis also exhibit differences in their interactions with membrane bilayers
role of rad51c and xrcc3 in genetic recombination and dna repair
mutant presenilin 1 alters synaptic transmission in cultured hippocampal neurons
structural and biochemical characterization of a cyanobacterium circadian clock-modifier protein
a hydrophobic patch in a charged -helix is sufficient to target proteins to dense core secretory granules
sequestration of retinyl esters is essential for retinoid signaling in the zebrafish embryo
forebrain-specific expression of monoamine oxidase a reduces neurotransmitter levels, restores the brain structure, and rescues aggressive behavior in monoamine oxi..
degradation of nfat5, a transcriptional regulator of osmotic stress-related genes, is a critical event for doxorubicin-induced cytotoxicity in cardiac myocytes
srcasm corrects fyn-induced epidermal hyperplasia by kinase down-regulation
optical manipulation reveals strong attracting forces at membrane contact sites between endoplasmic reticulum and chloroplasts
residues his-15 and arg-17 of hpr participate differently in catabolite signal processing via ccpa
specific aquaporins facilitate the diffusion of hydrogen peroxide across membranes
matrix macromolecules in hard tissues control the nucleation and hierarchical assembly of hydroxyapatite
g protein-coupled receptor kinase 2-mediated phosphorylation of downstream regulatory element antagonist modulator regulates membrane trafficking of kv4.2 potassium..
the molecular basis for ligand specificity in a mouse olfactory receptor
wnt-mediated down-regulation of sp1 target genes by a transcriptional repressor sp5
characterization of the interleukin (il)-6 inhibitor il-6-rfp
identification of ligand binding site of phytosulfokine receptor by on-column photoaffinity labeling
phosphoinositide 3-kinase c2 links clathrin to microtubule-dependent movement
the c-terminal domain of the escherichia coli waaj glycosyltransferase is important for catalytic activity and membrane association
hyaluronan-cd44 interaction with neural wiskott-aldrich syndrome protein (n-wasp) promotes actin polymerization and erbb2 activation leading to -catenin nuclear tra..
deregulation of the secyeg translocation channel upon removal of the plug domain
proapoptotic nix activates the jnk pathway by interacting with posh and mediates death in a parkinson disease model
structural basis for the platelet-collagen interaction
identification of the non-lysosomal glucosylceramidase as -glucosidase 2
insertion and topology of normal and mutant bestrophin-1 in the endoplasmic reticulum membrane
picornavirus internal ribosome entry site elements can stimulate translation of upstream genes
a novel nuclear interactor of arf and mdm2 (niam) that maintains chromosomal stability
metacaspase activity of arabidopsis thaliana is regulated by s-nitrosylation of a critical cysteine residue
leptin transcriptionally enhances peptide transporter (hpept1) expression and activity via the camp-response element-binding protein and cdx2 transcription factors
visualization of galectin-3 oligomerization on the surface of neutrophils and endothelial cells using fluorescence resonance energy transfer
role for neutral sphingomyelinase-2 in tumor necrosis factor -stimulated expression of vascular cell adhesion molecule-1 (vcam) and intercellular adhesion molecule-..
increased flexibility enhances misincorporation
repetitive deformation activates focal adhesion kinase and erk mitogenic signals in human caco-2 intestinal epithelial cells through src and rac1
evidence against a direct interaction between intracellular carbonic anhydrase ii and pure c-terminal domains of slc4 bicarbonate transporters
substrate conformation modulates aggrecanase (adamts-4) affinity and sequence specificity
a trimetal site and substrate distortion in a family ii inorganic pyrophosphatase
structural and biochemical investigation of the role in proofreading of a hairpin loop found in the exonuclease domain of a replicative dna polymerase of the b family
sr-bi undergoes cholesterol-stimulated transcytosis to the bile canaliculus in polarized wif-b cells
sulfolobus solfataricus dna polymerase dpo4 is partially inhibited by “wobble“ pairing between o6-methylguanine and cytosine, but accurate bypass is preferred
growth hormone corrects proliferation and transcription of phosphoenolpyruvate carboxykinase in livers of old mice via elimination of ccaat/enhancer-binding protein..
coordinate suppression of erbb2 and erbb3 by enforced expression of micro-rna mir-125a or mir-125b
rab gtpases containing a caax motif are processed post-geranylgeranylation by proteolysis and methylation
targeted cyclooxygenase gene (ptgs) exchange reveals discriminant isoform functionality
genetic evidence for adenylyl cyclase 1 as a target for preventing neuronal excitotoxicity mediated by n-methyl-d-aspartate receptors
sirt1 inhibits transforming growth factor -induced apoptosis in glomerular mesangial cells via smad7 deacetylation
food intake regulates oleoylethanolamide formation and degradation in the proximal small intestine
metastasis tumor antigens, an emerging family of multifaceted master coregulators
understanding a transcriptional paradigm at the molecular level
fas-activated serine/threonine kinase (fast k) synergizes with tia-1/tiar proteins to regulate fas alternative splicing
stress-induced c-jun-dependent vitamin d receptor (vdr) activation dissects the non-classical vdr pathway from the classical vdr activity
hydrodynamic studies on the quaternary structure of recombinant mouse pur
thioredoxin-dependent enzymatic activation of mercaptopyruvate sulfurtransferase
abrogation of the transactivation activity of p53 by bccip down-regulation
glucose induces mafa expression in pancreatic beta cell lines via the hexosamine biosynthetic pathway
biochemical differentiation of apobec3f and apobec3g proteins associated with hiv-1 life cycle
streptococcus pneumoniae sheds syndecan-1 ectodomains through zmpc, a metalloproteinase virulence factor
doxorubicin down-regulates krüppel-associated box domain-associated protein 1 sumoylation that relieves its transcription repression on p21waf1/cip1 in breast canc..
calcineurin regulates skeletal muscle metabolism via coordinated changes in gene expression
the hemolymph of the ascidian styela plicata (chordata-tunicata) contains heparin inside basophil-like cells and a unique sulfated galactoglucan in the plasma
lipid homeostasis and lipoprotein secretion in niemann-pick c1-deficient hepatocytes
ligand dynamics in an electron transfer protein
rbck1, a protein kinase ci (pkci)-interacting protein, regulates pkc-dependent function
ubpy-mediated epidermal growth factor receptor (egfr) de-ubiquitination promotes egfr degradation
a role for lte1p (a low temperature essential protein involved in mitosis) in proprotein processing in the yeast secretory pathway
biochemical and functional analysis of the assembly of full-length sup35p and its prion-forming domain
mip/lin-9 regulates the expression of b-myb and the induction of cyclin a, cyclin b, and cdk1
yersinia protein kinase yopo is activated by a novel g-actin binding process
cancer cell cycle modulated by a functional coupling between sigma-1 receptors and cl- channels
activation of shp2 protein-tyrosine phosphatase increases hoxa10-induced repression of the genes encoding gp91phox and p67phox
mutations in the sf1-u2af59-u2af23 complex cause exon skipping in schizosaccharomyces pombe
a role for protein misfolding in immunogenicity of biopharmaceuticals
foxo3a induces differentiation of bcr-abl-transformed cells through transcriptional down-regulation of id1
hu proteins regulate polyadenylation by blocking sites containing u-rich sequences
bacterial flavodoxins support nitric oxide production by bacillus subtilis nitric-oxide synthase
sustained jnk activation in response to tumor necrosis factor is mediated by caspases in a cell type-specific manner
regulation of the yeast tsa1 peroxiredoxin by zap1 is an adaptive response to the oxidative stress of zinc deficiency
the vp16 activation domain establishes an active mediator lacking cdk8 in vivo
the src homology 3 domain of the -subunit of voltage-gated calcium channels promotes endocytosis via dynamin interaction
kinetic mechanism of human myosin iiia
caspase inhibition blocks cell death and results in cell cycle arrest in cytokine-deprived hematopoietic cells
direct regulation of an oncogenic micro-rna cluster by e2f transcription factors
an e2f/mir-20a autoregulatory feedback loop
highly conserved residues asp-197 and his-250 in agp1 phytochrome control the proton affinity of the chromophore and pfr formation
the drosophila inhibitor of apoptosis (iap) diap2 is dispensable for cell survival, required for the innate immune response to gram-negative bacterial infection, an..
characterization of the plasmodium falciparum m17 leucyl aminopeptidase
cdc7 is an active kinase in human cancer cells undergoing replication stress
topology and membrane association of lecithin: retinol acyltransferase
direct demonstration of the flexibility of the glycosylated proline-threonine linker in the cellulomonas fimi xylanase cex through nmr spectroscopic analysis
the c-terminal domains of vertebrate cstf-64 and its yeast orthologue rna15 form a new structure critical for mrna 3‘-end processing
identification of the hydrophobic ligand binding pocket of the s1p1 receptor
in vivo and in vitro degradation of heparan sulfate (hs) proteoglycans by hpr1 in pancreatic adenocarcinomas
attenuation of bone mass and increase of osteoclast formation in decoy receptor 3 transgenic mice
sclip, a microtubule-destabilizing factor, interacts with rasgrf1 and inhibits its ability to promote rac activation and neurite outgrowth
inefficient proofreading and biased error rates during inaccurate dna synthesis by a mutant derivative of saccharomyces cerevisiae dna polymerase
activation of trpm7 channels by phospholipase c-coupled receptor agonists
chemical determinants involved in anandamide-induced inhibition of t-type calcium channels
serine and cysteine proteases are translocated to similar extents upon formation of covalent complexes with serpins
knock-out of the magnesium protoporphyrin ix methyltransferase gene in arabidopsis
mek-erk-mediated phosphorylation of mdm2 at ser-166 in hepatocytes
differential regulation of clusterin and its isoforms by androgens in prostate cells
the histone chaperone anti-silencing function 1 stimulates the acetylation of newly synthesized histone h3 in s-phase
substitutions at methionine 295 of archaeoglobus fulgidus ribulose-1,5-bisphosphate carboxylase/oxygenase affect oxygen binding and co2/o2 specificity
translational control of glial glutamate transporter eaat2 expression
suppression of calpain-dependent cleavage of the cdk5 activator p35 to p25 by site-specific phosphorylation
functional analysis of individual binding activities of the scaffold protein eif4g
monoclonal antibody clearance
carbon monoxide protects against hyperoxia-induced endothelial cell apoptosis by inhibiting reactive oxygen species formation
phosphorylation of the lfa-1 integrin 2-chain on thr-758 leads to adhesion, rac-1/cdc42 activation, and stimulation of cd69 expression in human t cells
control of adipose triglyceride lipase action by serine 517 of perilipin a globally regulates protein kinase a-stimulated lipolysis in adipocytes
a cadmium-transporting p1b-type atpase in yeast saccharomyces cerevisiae
a novel c-jun-dependent signal transduction pathway necessary for the transcriptional activation of interferon response genes
cell type-specific effect of hypoxia and platelet-derived growth factor-bb on extracellular matrix turnover and its consequences for lung remodeling
hyperactive variants of p38 induce, whereas hyperactive variants of p38 suppress, activating protein 1-mediated transcription
structural basis for the adherence of plasmodium falciparum-infected erythrocytes to chondroitin 4-sulfate and design of novel photoactivable reagents for the ident..
knock-out of the plastid-encoded petl subunit results in reduced stability and accelerated leaf age-dependent loss of the cytochrome b6f complex
essential roles for fe65, alzheimer amyloid precursor-binding protein, in the cellular response to dna damage
a single residue in the c1 domain sensitizes novel protein kinase c isoforms to cellular diacylglycerol production
-tocotrienol inhibits nuclear factor-b signaling pathway through inhibition of receptor-interacting protein and tak1 leading to suppression of antiapoptotic gene pr..
role of reduced lipoic acid in the redox regulation of mitochondrial aldehyde dehydrogenase (aldh-2) activity
galectin-3 interaction with thomsen-friedenreich disaccharide on cancer-associated muc1 causes increased cancer cell endothelial adhesion
deregulation of ap-1 proteins in collagen gel-induced epithelial cell apoptosis mediated by low substratum rigidity
feeding and insulin increase leptin translation
the liver x receptor (lxr) and hepatic lipogenesis
the human il-13 locus in neonatal cd4+ t cells is refractory to the acquisition of a repressive chromatin architecture
identification of neuregulin as a factor required for formation of aligned spermatogonia
requirement of non-canonical activity of uracil dna glycosylase for class switch recombination
cp1 mediates stabilization of htert mrna by autocrine human growth hormone
structural basis for p53 binding-induced dna bending
a udp-galnac:polypeptide n-acetylgalactosaminyltransferase is required for epithelial tube formation
the role of the ubiquitin ligase e6-ap in human papillomavirus e6-mediated degradation of pdz domain-containing proteins
inner nuclear membrane proteins asi1, asi2, and asi3 function in concert to maintain the latent properties of transcription factors stp1 and stp2
a model for agonism and antagonism in an ancient and ubiquitous camp-binding domain
differential expression of the b‘ regulatory subunit of protein phosphatase 2a modulates tyrosine hydroxylase phosphorylation and catecholamine synthesis
disease-associated mutations at copper ligand histidine residues of superoxide dismutase 1 diminish the binding of copper and compromise dimer stability
structural and spectroscopic characterization of p450 bm3 mutants with unprecedented p450 heme iron ligand sets
comparative analysis of retroviral and native promoters driving expression of 1,3-galactosyltransferase 3gal-t5 in human and mouse tissues
increased functional diversity of plant k+ channels by preferential heteromerization of the shaker-like subunits akt2 and kat2
human tfdp3, a novel dp protein, inhibits dna binding and transactivation by e2f
proteolytic processing of delta-like 1 by adam proteases
the cyclin-dependent kinase inhibitors p57 and p27 regulate neuronal migration in the developing mouse neocortex
functional characterization of syncytin-a, a newly murine endogenous virus envelope protein
structural characterization and oligomerization of pb1-f2, a proapoptotic influenza a virus protein
solution structure of the cytoplasmic region of na+/h+ exchanger 1 complexed with essential cofactor calcineurin b homologous protein 1
crystal structure of the hrdc domain of human werner syndrome protein, wrn
staphylococcus aureus subvert autophagy for induction of caspase-independent host cell death
crystal structure of 1-deoxy-d-xylulose 5-phosphate synthase, a crucial enzyme for isoprenoids biosynthesis
dissecting the senescence-like program in tumor cells activated by ras signaling
nutlin-3 protects kidney cells during cisplatin therapy by suppressing bax/bak activation
molecular mechanisms of transactivation and doxorubicin-mediated repression of survivin gene in cancer cells
structural characterization of the active site of the pduo-type atp:co(i)rrinoid adenosyltransferase from lactobacillus reuteri
impact of membrane fusion and proteolysis on spoiiq dynamics and interaction with spoiiiah
respiratory distress and neonatal lethality in mice lacking golgi 1,2-mannosidase ib involved in n-glycan maturation
human ikaros function in activated t cells is regulated by coordinated expression of its largest isoforms
preservation of antimicrobial properties of complement peptide c3a, from invertebrates to humans
polo-like kinases inhibited by wortmannin
stearoyl-coa desaturase-1 mediates the pro-lipogenic effects of dietary saturated fat
proteome-wide analysis in saccharomyces cerevisiae identifies several phd fingers as novel direct and selective binding modules of histone h3 methylated at either l..
membrane cholesterol content modulates clc-2 gating and sensitivity to oxidative stress
hypoxic regulation of id-1 and activation of the unfolded protein response are aberrant in neuroblastoma
pannexin-1 couples to maitotoxin- and nigericin-induced interleukin-1 release through a dye uptake-independent pathway
phosphorylation of glutamate receptor interacting protein 1 regulates surface expression of glutamate receptors
the expression of clcn7 and ostm1 in osteoclasts is coregulated by microphthalmia transcription factor
distinctive t cell-suppressive signals from nuclearized type 1 sphingosine 1-phosphate g protein-coupled receptors
the anti-rheumatic gold salt aurothiomalate suppresses interleukin-1-induced hyaluronan accumulation by blocking has1 transcription and by acting as a cox-2 transcr..
signaling of mitochondrial biogenesis following oxidant injury
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