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生物物理学杂志2006年第08期封面 购买


the essential role of the death domain kinase receptor-interacting protein in insulin growth factor-i-induced c-jun n-terminal kinase activation
mechanism of instability in abortive cycling by t7 rna polymerase
nuclear localization signal receptor affinity correlates with in vivo localization in saccharomyces cerevisiae
analysis of the complex between ca2+ channel -subunit and the rem gtpase
biochemical characterization of the structural zn2+ site in the bacillus subtilis peroxide sensor perr
an iron-induced nitric oxide burst precedes ubiquitin-dependent protein degradation for arabidopsis atfer1 ferritin gene expression
gpr92 as a new g12/13- and gq-coupled lysophosphatidic acid receptor that increases camp, lpa5
expression of and role for ovarian cancer g-protein-coupled receptor 1 (ogr1) during osteoclastogenesis
hemicentin assembly in the extracellular matrix is mediated by distinct structural modules
physical and functional interaction of fyn tyrosine kinase with a brain-enriched rho gtpase-activating protein tcgap
arsenic induces nad(p)h-quinone oxidoreductase i by disrupting the nrf2·keap1·cul3 complex and recruiting nrf2·maf to the antioxidant response element enhancer
up-regulation of per mrna expression by parathyroid hormone through a protein kinase a-creb-dependent mechanism in chondrocytes
intracellular dissemination of peroxidative stress
knockdown of mbp-1 in human prostate cancer cells delays cell cycle progression
mapk-activated protein kinase 2 deficiency in microglia inhibits pro-inflammatory mediator release and resultant neurotoxicity
the absolute structural requirement for a proline in the p3‘-position of bowman-birk protease inhibitors is surmounted in the minimized sfti-1 scaffold
characterization of human mucin muc1
huntingtin phosphorylation sites mapped by mass spectrometry
the n-terminal ricin propeptide influences the fate of ricin a-chain in tobacco protoplasts
characterization of the ab loop region of timp-
interdomain communication in dna topoisomerase ii
isolation and characterization of low sulfated heparan sulfate sequences with affinity for lipoprotein lipase
the htlv-i p30 interferes with tlr4 signaling and modulates the release of pro- and anti-inflammatory cytokines from human macrophages
indirubin enhances tumor necrosis factor-induced apoptosis through modulation of nuclear factor-b signaling pathway
conditional deletion of hypothalamic y2 receptors reverts gonadectomy-induced bone loss in adult mice
human dna polymerase n (poln) is a low fidelity enzyme capable of error-free bypass of 5s-thymine glycol
differential stability of thymidylate synthase 3‘-untranslated region polymorphic variants regulated by auf1
reactive oxygen species mediate the potentiating effects of atp on gabaergic synaptic transmission in the immature hippocampus
the proprotein convertase ski-1/s1p
increased prolyl 4-hydroxylase domain proteins compensate for decreased oxygen levels
binding and transport of metal ions at the dimer interface of the escherichia coli metal transporter yiip
enzymatic properties of human aminopeptidase a
properties of human igg1s engineered for enhanced binding to the neonatal fc receptor (fcrn)
roles of endogenously synthesized sterols in the endocytic pathway
nanomechanics of hemichannel conformations
protein kinase c (pkc)-annexin v interaction
anthrax toxin receptor 1/tumor endothelium marker 8 mediates cell spreading by coupling extracellular ligands to the actin cytoskeleton
determinants of the dual cofactor specificity and substrate cooperativity of the human mitochondrial nad(p)+-dependent malic enzyme
heparin potentiates the in vivo ectopic bone formation induced by bone morphogenetic protein-2
the synthesis, structural characterization, and receptor specificity of the -conotoxin vc1.1
genetic analysis of human orc2 reveals specific domains that are required in vivo for assembly and nuclear localization of the origin recognition complex
cytoskeleton/endoplasmic reticulum collapse induced by prostaglandin j2 parallels centrosomal deposition of ubiquitinated protein aggregates
the adaptor protein gab1 couples the stimulation of vascular endothelial growth factor receptor-2 to the activation of phosphoinositide 3-kinase
de facto nucleosome dynamics
stabilization of the tau exon 10 stem loop alters pre-mrna splicing
dual regulation of rho and rac by p120 catenin controls adipocyte plasma membrane trafficking
the ferrous-dioxygen intermediate in human cytochrome p450 3a
regulation of the pluripotency marker rex-1 by nanog and sox2
phosphorylation of the norepinephrine transporter at threonine 258 and serine 259 is linked to protein kinase c-mediated transporter internalization
the sarcolemmal calcium pump, -1 syntrophin, and neuronal nitric-oxide synthase are parts of a macromolecular protein complex
characterization of the stomatin domain involved in homo-oligomerization and lipid raft association
plant phenylacetaldehyde synthase is a bifunctional homotetrameric enzyme that catalyzes phenylalanine decarboxylation and oxidation
characterization of the gbpd-activated rap1 pathway regulating adhesion and cell polarity in dictyostelium discoideum
interaction of amsh with escrt-iii and deubiquitination of endosomal cargo
a novel repressor domain is required for maximal growth inhibition by the irf-1 tumor suppressor
unraveling new features of clindamycin interaction with functional ribosomes and dependence of the drug potency on polyamines
electron transfer by neuronal nitric-oxide synthase is regulated by concerted interaction of calmodulin and two intrinsic regulatory elements
functional characterization of the complement control protein homolog of herpesvirus saimiri
regulation of the dha operon of lactococcus lactis
n-glycosylation affects the molecular organization and stability of e-cadherin junctions
endosomal acidification and activation of nadph oxidase isoforms are upstream events in hyperosmolarity-induced hepatocyte apoptosis
the role of the phospho-cdk2/cyclin a recruitment site in substrate recognition
involvement of sumo modification in mbd1- and mcaf1-mediated heterochromatin formation
alcohol metabolism-mediated oxidative stress down-regulates hepcidin transcription and leads to increased duodenal iron transporter expression
redox regulation of -actin during integrin-mediated cell adhesion
physiological regulation of atp release at the apical surface of human airway epithelia
pp2a regulates bcl-2 phosphorylation and proteasome-mediated degradation at the endoplasmic reticulum
the redox-bohr group associated with iron-sulfur cluster n2 of complex i
allosteric activation of coagulation factor viia visualized by hydrogen exchange
increased cug triplet repeat-binding protein-1 predisposes to impaired adipogenesis with aging
the specificity and function of the metal-binding sites in the integrin 3 a-domain
structure of the hemolysin e (hlye, clya, and shea) channel in its membrane-bound form
the transmembrane domain of glycoprotein ib is critical to efficient expression of glycoprotein ib-ix complex in the plasma membrane
constitutive and uv-induced fibronectin degradation is a ubiquitination-dependent process controlled by -trcp
heparin modulates the 99-loop of factor ixa
functional divergence of a unique c-terminal domain of leucyl-trna synthetase to accommodate its splicing and aminoacylation roles
the role of the stas domain in the function and biogenesis of a sulfate transporter as probed by random mutagenesis
interaction of tlr2 and tlr4 ligands with the n-terminal domain of gp96 amplifies innate and adaptive immune responses
effect of mutations in tom40 on stability of the translocase of the outer mitochondrial membrane (tom) complex, assembly of tom40, and import of mitochondrial prepr..
yke4 (yil023c) encodes a bidirectional zinc transporter in the endoplasmic reticulum of saccharomyces cerevisiae
cell-specific regulation of hypoxia-inducible factor (hif)-1 and hif-2 stabilization and transactivation in a graded oxygen environment
b-raf is critical for mapk activation during mitosis and is regulated in an m phase-dependent manner in xenopus egg extracts
peroxisome proliferator-activated receptor-1 is dephosphorylated and degraded during bay 11-7085-induced synovial fibroblast apoptosis
a transmembrane leucine zipper is required for activation of the dimeric receptor tyrosine kinase ddr1
the e and g subunits of the yeast v-atpase interact tightly and are both present at more than one copy per v1 complex
colicin m exerts its bacteriolytic effect via enzymatic degradation of undecaprenyl phosphate-linked peptidoglycan precursors
inositol induces a profound alteration in the pattern and rate of synthesis and turnover of membrane lipids in saccharomyces cerevisiae
carba analogs of cyclic phosphatidic acid are selective inhibitors of autotaxin and cancer cell invasion and metastasis
three new nudix hydrolases from escherichia coli
protein kinase c activates protein kinase b/akt via dna-pk to protect against tumor necrosis factor--induced cell death
helix packing of the cardiac na+-ca2+ exchanger
cold exposure stimulates synthesis of the bioactive lipid oleoylethanolamide in rat adipose tissue
mitochondrial protein sorting
the single ligand-binding repeat of tva, a low density lipoprotein receptor-related protein, contains two ligand-binding surfaces
the bloom‘s syndrome helicase can promote the regression of a model replication fork
metabolic inactivation of resolvin e1 and stabilization of its anti-inflammatory actions
the novel sparc family member smoc-2 potentiates angiogenic growth factor activity
iron regulation and the cell cycle
14-3-3 mediates transcriptional regulation by modulating nucleocytoplasmic shuttling of tobacco dna-binding protein phosphatase-1
comprehensive analysis of expression and function of 51 sarco(endo)plasmic reticulum ca2+-atpase mutants associated with darier disease
crystal structure of the second lns/lg domain from neurexin
characterizing the tick carboxypeptidase inhibitor
translation initiation factor eif4g-1 binds to eif3 through the eif3e subunit
novel polyphenol oxidase mined from a metagenome expression library of bovine rumen
switch from caspase-dependent to caspase-independent death during heart development
characterization of alternative cytosolic forms and cellular targets of mouse mitochondrial thioredoxin reductase
comprehensive and quantitative mapping of energy landscapes for protein-protein interactions by rapid combinatorial scanning
chiral mutagenesis of insulin
the transforming growth factor--smad3/4 signaling pathway acts as a positive regulator for tlr2 induction by bacteria via a dual mechanism involving functional coop..
the relationship between intranuclear mobility of the nf-b subunit p65 and its dna binding affinity
the subunit of the granulocyte-macrophage colony-stimulating factor receptor interacts with c-kit and inhibits c-kit signaling
the crystal structure of a human pp2a phosphatase activator reveals a novel fold and highly conserved cleft implicated in protein-protein interactions
synthetic lethal and biochemical analyses of nad and nadh kinases in saccharomyces cerevisiae establish separation of cellular functions
activation of the mitogen- and stress-activated kinase 1 by arsenic trioxide
candida albicans cell wall ssa proteins bind and facilitate import of salivary histatin 5 required for toxicity
a new type of bacterial sulfatase reveals a novel maturation pathway in prokaryotes
suppression and overexpression of adenosylhomocysteine hydrolase-like protein 1 (ahcyl1) influences zebrafish embryo development
protective mechanisms against homocysteine toxicity
mrs3p, mrs4p, and frataxin provide iron for fe-s cluster synthesis in mitochondria
protective effects of neurotrophic factors on tumor necrosis factor-related apoptosis-inducing ligand (trail)-mediated apoptosis of murine adrenal chromaffin cell l..
variation in ligand binding specificities of a novel class of poxvirus-encoded tumor necrosis factor-binding protein
a novel function of plasminogen activator inhibitor-1 in modulation of the akt pathway in wild-type and plasminogen activator inhibitor-1-deficient endothelial cells
role of bmi1 in h2a ubiquitylation and hox gene silencing
comparative structural analysis of the erbin pdz domain and the first pdz domain of zo-
dynamic sequestration of the recycling compartment by classical protein kinase c
association of catsper1 or -2 with cav3.3 leads to suppression of t-type calcium channel activity
compensatory responses to pyruvate carboxylase suppression in islet -cells
interaction between fidgetin and protein kinase a-anchoring protein akap95 is critical for palatogenesis in the mouse
rate of rupture and reattachment of the band 3-ankyrin bridge on the human erythrocyte membrane
crystal structure and mutational analysis of the daae adhesin of escherichia coli
c-jun n-terminal kinase is necessary for platelet-derived growth factor-mediated chemotaxis in primary fibroblasts
modulation of gabaa receptor phosphorylation and membrane trafficking by phospholipase c-related inactive protein/protein phosphatase 1 and 2a signaling complex und..
a basic leucine zipper transcription factor, g-box-binding factor 1, regulates blue light-mediated photomorphogenic growth in arabidopsis
a single chondroitin 6-sulfate oligosaccharide unit at ser-2730 of human thyroglobulin enhances hormone formation and limits proteolytic accessibility at the carbox..
conservation of structure and mechanism in primary and secondary transporters exemplified by siap, a sialic acid binding virulence factor from haemophilus influenzae
cell cycle-controlled interaction of nucleolin with the retinoblastoma protein and cancerous cell transformation
structural determinants that target the hepatitis c virus core protein to lipid droplets
fission yeast mcm10p contains primase activity
mechanism of assembly of g protein subunits by protein kinase ck2-phosphorylated phosducin-like protein and the cytosolic chaperonin complex
calcium-independent phospholipase a2 localizes in and protects mitochondria during apoptotic induction by staurosporine
autosomal recessive retinitis pigmentosa and e150k mutation in the opsin gene
convergent and divergent ligand specificity among pdz domains of the lap and zonula occludens (zo) families
the oxygen transport system in three species of the boreal fish family gadidae
cacna1h mutations in autism spectrum disorders
identification of a lithium interaction site in the -aminobutyric acid (gaba) transporter gat-1
up-regulation of skp2 after prostate cancer cell adhesion to basement membranes results in brca2 degradation and cell proliferation
modifications in thermus thermophilus 23 s ribosomal rna are centered in regions of rna-rna contact
proteasome inhibitors induce death but activate nf-b on endometrial carcinoma cell lines and primary culture explants
the structure of an ancient conserved domain establishes a structural basis for stable histidine phosphorylation and identifies a new family of adenosine-specific k..
glucose acutely decreases ph of secretory granules in mouse pancreatic islets
site-specific labeling of cytoplasmic peptide:n-glycanase by n,n‘-diacetylchitobiose-related compounds
apobec3 proteins inhibit human line-1 retrotransposition
role of dna methyltransferases in regulation of human ribosomal rna gene transcription
antagonism or synergism
the interaction of thioredoxin with txnip
nitric oxide binding to prokaryotic homologs of the soluble guanylate cyclase 1 h-nox domain
cholesterol precursors stabilize ordinary and ceramide-rich ordered lipid domains (lipid rafts) to different degrees
modulation of the viral atpase activity by the portal protein correlates with dna packaging efficiency
de-epoxidation of violaxanthin in the minor antenna proteins of photosystem ii, lhcb4, lhcb5, and lhcb6
effects of common cancer mutations on stability and dna binding of full-length p53 compared with isolated core domains
the neuronal ca2+ sensor protein visinin-like protein-1 is expressed in pancreatic islets and regulates insulin secretion
distinct role of the n-terminal tail of the na,k-atpase catalytic subunit as a signal transducer
molecular characterization of trypanosoma brucei p-type h+-atpases
an outer membrane enzyme encoded by salmonella typhimurium lpxr that removes the 3‘-acyloxyacyl moiety of lipid a
identification and functional characterization of the moss physcomitrella patens 5-desaturase gene involved in arachidonic and eicosapentaenoic acid biosynthesis
endoplasmic reticulum stress associated with extracellular aggregates
the crystal structure of human geranylgeranyl pyrophosphate synthase reveals a novel hexameric arrangement and inhibitory product binding
transforming growth factor--activated kinase 1 is essential for differentiation and the prevention of apoptosis in epidermis
kynurenic acid as a ligand for orphan g protein-coupled receptor gpr35
utilization of an amphipathic leucine zipper sequence to design antibacterial peptides with simultaneous modulation of toxic activity against human red blood cells
opposing roles of wnt-5a and wnt-11 in interleukin-1 regulation of type ii collagen expression in articular chondrocytes
oligomerizing potential of a focal adhesion lim protein hic-5 organizing a nuclear-cytoplasmic shuttling complex
the wnt co-receptor lrp5 is essential for skeletal mechanotransduction but not for the anabolic bone response to parathyroid hormone treatment
phosphorylation of amphiphysin i by minibrain kinase/dual-specificity tyrosine phosphorylation-regulated kinase, a kinase implicated in down syndrome
direct involvement of the small gtpase rac in activation of the superoxide-producing nadph oxidase nox1
metabolic profiling of glycerophospholipid synthesis in fibroblasts loaded with free cholesterol and modified low density lipoproteins
the globular tail domain of myosin va functions as an inhibitor of the myosin va motor
mathematical modeling of polyamine metabolism in mammals
co-translational binding of groel to nascent polypeptides is followed by post-translational encapsulation by groes to mediate protein folding
two point mutations of rpe65 from patients with retinal dystrophies decrease the stability of rpe65 protein and abolish its isomerohydrolase activity
oxidant-induced activation of type i protein kinase a is mediated by ri subunit interprotein disulfide bond formation
cyclic amp-dependent and epac-mediated activation of r-ras by g protein-coupled receptors leads to phospholipase d stimulation
coordinated regulation of aib1 transcriptional activity by sumoylation and phosphorylation
two frameshift products involved in the transposition of bacterial insertion sequence is629
sumoylation of ccaat/enhancer-binding protein and its functional roles in hepatocyte differentiation
conjugation to nedd8 instigates ubiquitylation and down-regulation of activated receptor tyrosine kinases
proteasome inhibition down-regulates endothelial nitric-oxide synthase phosphorylation and function
quality control of photosystem ii
steady-state kinetic mechanism of pdk1
productive folding of tyrosinase ectodomain is controlled by the transmembrane anchor
neuregulins mediate calcium-induced glucose transport during muscle contraction
specificity protein 1-dependent p53-mediated suppression of human manganese superoxide dismutase gene expression
geldanamycins trigger a novel ron degradative pathway, hampering oncogenic signaling
a macromolecular complex formed by a pilin-like protein in competent bacillus subtilis
characterization of acatalasemic erythrocytes treated with low and high dose hydrogen peroxide
regulated adam10-dependent ectodomain shedding of -protocadherin c3 modulates cell-cell adhesion
neuronal sirt1 activation as a novel mechanism underlying the prevention of alzheimer disease amyloid neuropathology by calorie restriction
characterization of the hiv n-terminal fusion peptide-containing region in context of key gp41 fusion conformations
functional characterization of two nucleotide-binding sites in soluble guanylate cyclase
surfactant protein a directly interacts with tlr4 and md-2 and regulates inflammatory cellular response
an interaction involving an arginine residue in the cytoplasmic domain of the 5-ht3a receptor contributes to receptor desensitization mechanism
the crystal structure of the primary ca2+ sensor of the na+/ca2+ exchanger reveals a novel ca2+ binding motif
a functional genetic screen identifies tfe3 as a gene that confers resistance to the anti-proliferative effects of the retinoblastoma protein and transforming growt..
fine tuning pdk1 activity by phosphorylation at ser163
insulin reverses growth hormone-induced homologous desensitization
regulation of replication protein a functions in dna mismatch repair by phosphorylation
a basolateral sorting signal directs adam10 to adherens junctions and is required for its function in cell migration
ca2+ and mg2+ binding properties of gcap-
peroxisome proliferator-activated receptor -regulated abcg2 expression confers cytoprotection to human dendritic cells
characterization of mechanisms involved in secretion of active heparanase
molecular dynamics simulations show that bound mg2+ contributes to amino acid and aminoacyl adenylate binding specificity in aspartyl-trna synthetase through long r..
role of the activation loop tyrosines in regulation of the insulin-like growth factor i receptor-tyrosine kinase
conformational basis for sh2-tyr(p)527 binding in src inactivation
phospholipid translocation and miltefosine potency require both l. donovani miltefosine transporter and the new protein ldros3 in leishmania parasites
cooperativity between the hydrophobic and cross-linking domains of elastin
the novel pias-like protein hzimp10 enhances smad transcriptional activity
k+-independent actions of diazoxide question the role of inner membrane katp channels in mitochondrial cytoprotective signaling
the kcne2 potassium channel ancillary subunit is essential for gastric acid secretion
a strong glutathione s-transferase inhibitor overcomes the p-glycoprotein-mediated resistance in tumor cells
regulation of nucleocytoplasmic trafficking of transcription factor orebp/tonebp/nfat5
alteration of sequence specificity of the type ii restriction endonuclease hincii through an indirect readout mechanism
archaeal proteasomes effectively degrade aggregation-prone proteins and reduce cellular toxicities in mammalian cells
skp2 contains a novel cyclin a binding domain that directly protects cyclin a from inhibition by p27kip1
catalytic mechanism and structure of viral flavin-dependent thymidylate synthase thyx
analysis of tetramethylrhodamine-labeled actin polymerization and interaction with actin regulatory proteins
structural analyses on intermediates in serine protease catalysis
a carboxyl-terminal hydrophobic interface is critical to sodium channel function
stable association between gq and phospholipase c1 in living cells
crystal structures of chloroperoxidase with its bound substrates and complexed with formate, acetate, and nitrate
structural basis for d-amino acid transamination by the pyridoxal 5‘-phosphate-dependent catalytic antibody 15a9
role of the phox homology domain and phosphorylation in activation of serum and glucocorticoid-regulated kinase-3
phosphatidylinositol 3-kinase-dependent suppression of the human inducible nitric-oxide synthase promoter is mediated by fkhrl1
a minimal promoter for tfiiic-dependent in vitro transcription of snorna and trna genes by rna polymerase iii
regulation of akap-membrane interactions by calcium
a conserved 12-amino acid motif in sall1 recruits the nucleosome remodeling and deacetylase corepressor complex
different domains of the ampa receptor direct stargazin-mediated trafficking and stargazin-mediated modulation of kinetics
apop-1, a novel protein inducing cyclophilin d-dependent but bax/bak-related channel-independent apoptosis
effects of c-terminal truncations on trafficking of the yeast plasma membrane h+-atpase
multiple endoplasmic reticulum-to-nucleus signaling pathways coordinate phospholipid metabolism with gene expression by distinct mechanisms
sall4 interacts with nanog and co-occupies nanog genomic sites in embryonic stem cells
shear and compression differentially regulate clusters of functionally related temporal transcription patterns in cartilage tissue
the 1--subunit interaction that modulates calcium channel activity is reversible and requires a competent -interaction domain
reishi polysaccharides induce immunoglobulin production through the tlr4/tlr2-mediated induction of transcription factor blimp-1
protein kinase c is up-regulated in osteoarthritic cartilage and is required for activation of nf-b by tumor necrosis factor and interleukin-1 in articular chondroc..
identification of common transcriptional regulatory elements in interleukin-17 target genes
the chicken ovalbumin upstream promoter-transcription factors modulate genes and pathways involved in skeletal muscle cell metabolism
brca1 interacts with poly(a)-binding protein
stimulation of hiv-1 minus strand strong stop dna transfer by genomic sequences 3‘ of the primer binding site
using model proteins to quantify the effects of pathogenic mutations in ig-like proteins
the metabotropic glutamate g-protein-coupled receptors mglur3 and mglur1a are voltage-sensitive
structural determinants of salmon calcitonin bioactivity
tumor necrosis factor induces spermidine/spermine n1-acetyltransferase through nuclear factor bin non-small cell lung cancer cells
transforming growth factor 1 induces hypoxia-inducible factor-1 stabilization through selective inhibition of phd2 expression
dna damage-induced down-regulation of human cdc25c and cdc2 is mediated by cooperation between p53 and maintenance dna (cytosine-5) methyltransferase 1
homophilic interactions of tetraspanin cd151 up-regulate motility and matrix metalloproteinase-9 expression of human melanoma cells through adhesion-dependent c-jun..
raloxifene increases proliferation and up-regulates telomerase activity in human umbilical vein endothelial cells
mapkapk-2 is a critical signaling intermediate in nhe3 activation following na+-glucose cotransport
the circadian clock within the cardiomyocyte is essential for responsiveness of the heart to fatty acids
rbm4 interacts with an intronic element and stimulates tau exon 10 inclusion
interaction of human lactoferrin with cell adhesion molecules through rgd motif elucidated by lactoferrin-binding epitopes
locating the carboxylate group of gaba in the homomeric rho gabaa receptor ligand-binding pocket
a new rubisco-like protein coexists with a photosynthetic rubisco in the planktonic cyanobacteria microcystis
saccharomyces boulardii inhibits erk1/2 mitogen-activated protein kinase activation both in vitro and in vivo and protects against clostridium difficile toxin a-ind..
observed instability of t7 rna polymerase elongation complexes can be dominated by collision-induced “bumping“
the role of the s4-s5 linker and c-terminal tail in inositol 1,4,5-trisphosphate receptor function
distinct early folding and aggregation properties of alzheimer amyloid- peptides a40 and a4
pescadillo interacts with the cadmium response element of the human heme oxygenase-1 promoter in renal epithelial cells
cyclooxygenase-2 induction by arsenite is through a nuclear factor of activated t-cell-dependent pathway and plays an antiapoptotic role in beas-2b cells
ccaat/enhancer-binding protein mediates induction of hepatic phosphoenolpyruvate carboxykinase by p38 mitogen-activated protein kinase
ai-1 influences the kinase activity but not the phosphatase activity of luxn of vibrio harveyi
osteopontin induction of hyaluronan synthase 2 expression promotes breast cancer malignancy
syndecan-1 expression in epithelial cells is induced by transforming growth factor through a pka-dependent pathway
hierarchic finite level energy landscape model
wheat eukaryotic initiation factor 4b organizes assembly of rna and eifiso4g, eif4a, and poly(a)-binding protein
tracking the unfolding pathway of a multirepeat protein via tryptophan scanning
p38 mitogen-activated protein kinase mediates free fatty acid-induced gluconeogenesis in hepatocytes
phosphorylation of protein phosphatase inhibitor-1 by protein kinase c
role of single-stranded dna in targeting rev1 to primer termini
regulation of the mdm2-p53 pathway by ribosomal protein l11 involves a post-ubiquitination mechanism
activation of mammalian target of rapamycin (mtor) by insulin is associated with stimulation of 4ebp1 binding to dimeric mtor complex 1
structural studies of flaa1 from helicobacter pylori reveal the mechanism for inverting 4,6-dehydratase activity
dimerization of the scaffolding protein zo-1 through the second pdz domain
coupling of agonist binding to effector domain activation in metabotropic glutamate-like receptors
a specific isoform of nonmuscle myosin ii-c is required for cytokinesis in a tumor cell line
pathway of information transmission from heme to protein upon ligand binding/dissociation in myoglobin revealed by uv resonance raman spectroscopy
conserved sequence box ii directs transcription termination and primer formation in mitochondria
transcription of human zinc finger znf268 gene requires an intragenic promoter element
suppression of the ligand-mediated down-regulation of epidermal growth factor receptor by ymer, a novel tyrosine-phosphorylated and ubiquitinated protein
transcriptional regulation of uterine vascular endothelial growth factor during early gestation in a carnivore model, mustela vison
nonsecreted insulin-like growth factor binding protein-3 (igfbp-3) can induce apoptosis in human prostate cancer cells by igf-independent mechanisms without being c..
peroxisome proliferator-activated receptor promotes epithelial to mesenchymal transformation by rho gtpase-dependent activation of erk1/2
matrix metalloproteinase-9 degrades amyloid- fibrils in vitro and compact plaques in situ
glutamate inhibits chondral mineralization through apoptotic cell death mediated by retrograde operation of the cystine/glutamate antiporter
regulation of murine tgf2 by pax3 during early embryonic development
non-b dna conformations formed by long repeating tracts of myotonic dystrophy type 1, myotonic dystrophy type 2, and friedreich‘s ataxia genes, not the sequences p..
fe65 interaction with the apoe receptor apoer2
molecular basis of partial agonism at the neurotransmitter 2a-adrenergic receptor and gi-protein heterotrimer
conformational mobility in the active site of a heme peroxidase
correction of pulmonary abnormalities in sftpd-/- mice requires the collagenous domain of surfactant protein d
acid ceramidase but not acid sphingomyelinase is required for tumor necrosis factor--induced pge2 production
structure-function relationships in the neuropeptide s receptor
saccharomyces cerevisiae hog1 protein phosphorylation upon exposure to bacterial endotoxin
-conotoxin omia is a potent ligand for the acetylcholine-binding protein as well as 32 and 7 nicotinic acetylcholine receptors
catalytic importance of acidic amino acids on subunit nuob of the escherichia coli nadh:ubiquinone oxidoreductase (complex i)
tumor suppressor p16ink4a regulates polycomb-mediated dna hypermethylation in human mammary epithelial cells
serotonin-, protein kinase c-, and hic-5-associated redistribution of the platelet serotonin transporter
identification of a novel class of nicotinic receptor antagonists
dimerization of substrate adaptors can facilitate cullin-mediated ubiquitylation of proteins by a “tethering“ mechanism
the nug1 gtpase reveals an n-terminal rna-binding domain that is essential for association with 60 s pre-ribosomal particles
androcam is a tissue-specific light chain for myosin vi in the drosophila testis
regulation of survivin stability by the aryl hydrocarbon receptor-interacting protein
his-384 allotypic variant of factor h associated with age-related macular degeneration has different heparin binding properties from the non-disease-associated form
the corticotropin-releasing factor receptor type 2a contains an n-terminal pseudo signal peptide
toward the active conformation of insulin
a conserved histidine in insulin is required for the foldability of human proinsulin
high resolution structures of p-aminobenzamidine- and benzamidine-viia/soluble tissue factor
the role of integrin-linked kinase in liver wound healing
intrinsic kinase activity and sq/tq domain of chk2 kinase as well as n-terminal domain of wip1 phosphatase are required for regulation of chk2 by wip1
modulation of stat3 activation by the cytosolic phospholipase a2 and cyclooxygenase-2-controlled prostaglandin e2 signaling pathway
structural analysis of protein kinase a mutants with rho-kinase inhibitor specificity
cellular uptake of exogenous human pdcd5 protein
crystal structures of clostridium thermocellum xyloglucanase, xgh74a, reveal the structural basis for xyloglucan recognition and degradation
the crystal structure of iron-free human serum transferrin provides insight into inter-lobe communication and receptor binding
association of calpastatin with inactive calpain
control of template positioning during de novo initiation of rna synthesis by the bovine viral diarrhea virus ns5b polymerase
large store-operated calcium selective currents due to co-expression of orai1 or orai2 with the intracellular calcium sensor, stim1
identification of neurite outgrowth-promoting domains of neuroglycan c, a brain-specific chondroitin sulfate proteoglycan, and involvement of phosphatidylinositol 3..
an -glucan of pseudallescheria boydii is involved in fungal phagocytosis and toll-like receptor activation
protein phosphatase 6 subunit with conserved sit4-associated protein domain targets ib
the replication intermediates in escherichia coli are not the product of dna processing or uracil excision
comprehensive examination of charged intramembrane residues in a nucleoside transporter
the swi/snf chromatin remodeling subunit baf57 is a critical regulator of estrogen receptor function in breast cancer cells
non-optimal tata elements exhibit diverse mechanistic consequences
mismatch repair-dependent iterative excision at irreparable o6-methylguanine lesions in human nuclear extracts
separation and identification of major plant sphingolipid classes from leaves
chromatin remodeling and transcriptional activity of the bone-specific osteocalcin gene require ccaat/enhancer-binding protein -dependent recruitment of swi/snf act..
relationship between the oligomeric status of hiv-1 integrase on dna and enzymatic activity
mitochondrial dna depletion and thymidine phosphate pool dynamics in a cellular model of mitochondrial neurogastrointestinal encephalomyopathy
bok, bcl-2-related ovarian killer, is cell cycle-regulated and sensitizes to stress-induced apoptosis
inhibition of early steps of hiv-1 replication by snf5/ini1
identification of an antiangiogenic fgf2-binding site in the n terminus of the soluble pattern recognition receptor ptx3
control of chemotactic signal gain via modulation of a pre-formed receptor array
vasoactive intestinal peptide and pacap38 control n-methyl-d-aspartic acid-induced dendrite motility by modifying the activities of rho gtpases and phosphatidylinos..
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