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生物物理学杂志2006年第05期封面 购买


mechanistic differences in actin bundling activity of two mammalian formins, frl1 and mdia2
altered folding, turnover, and polarized sorting act in concert to define a novel pathomechanism of congenital sucrase-isomaltase deficiency
molecular mechanism of the reduction of cysteine sulfinic acid of peroxiredoxin to cysteine by mammalian sulfiredoxin
lipid dependence of the channel properties of a colicin e1-lipid toroidal pore
interactions between pias proteins and sox9 result in an increase in the cellular concentrations of sox9
differential regulation of interleukin 5-stimulated signaling pathways by dynamin
induction of adaptive response and enhancement of pc12 cell tolerance by 7-hydroxycholesterol and 15-deoxy-12,14-prostaglandin j2 through up-regulation of cellular ..
bcl2 suppresses dna repair by enhancing c-myc transcriptional activity
localization of sites of interaction between p23 and hsp90 in solution
cytoplasmic function of mutant promyelocytic leukemia (pml) and pml-retinoic acid receptor-
regulation of intracellular accumulation of mutant huntingtin by beclin 1
epidermal growth factor receptor exposed to oxidative stress undergoes src- and caveolin-1-dependent perinuclear trafficking
n-terminal region of ccaat/enhancer-binding protein is critical for cell cycle arrest, apoptosis, and functional maturation during myeloid differentiation
the electron transfer complex between cytochrome c552 and the cua domain of the thermus thermophilus ba3 oxidase
molecular basis of formaldehyde detoxification
enolase activates homotypic vacuole fusion and protein transport to the vacuole in yeast
regulation of ornithine decarboxylase
syndecan-2 is expressed in the microvasculature of gliomas and regulates angiogenic processes in microvascular endothelial cells
pharmacological chaperone activity of sr49059 to functionally recover misfolded mutations of the vasopressin v1a receptor
identification of the key residues responsible for the assembly of selenodeiodinases
functions of erp57 in the folding and assembly of major histocompatibility complex class i molecules
interleukin-1 enhances gabaa receptor cell-surface expression by a phosphatidylinositol 3-kinase/akt pathway
distinct glycan structures of uroplakins ia and ib
brca1 modulates xenobiotic stress-inducible gene expression by interacting with arnt in human breast cancer cells
profiling of eicosanoid production in the rat hippocampus during kainic acid-induced seizure
c-terminal fragment of presenilin is the molecular target of a dipeptidic -secretase-specific inhibitor dapt (n-[n-(3,5-difluorophenacetyl)-l-alanyl]-s-phenylglycin..
targeting of calcineurin to an nfat-like docking site is required for the calcium-dependent activation of the background k+ channel, tresk
partnership of pgc-1 and hnf4 in the regulation of lipoprotein metabolism
regulation of aurora-a kinase gene expression via gabp recruitment of trap220/med1
attenuation of peroxisome proliferator-activated receptor (ppar) mediates gastrin-stimulated colorectal cancer cell proliferation
klf5 interacts with p53 in regulating survivin expression in acute lymphoblastic leukemia
active transcription of the human fasl/cd95l/tnfsf6 promoter region in t lymphocytes involves chromatin remodeling
pleiotropic effects of atp·mg2+ binding in the catalytic cycle of ubiquitin-activating enzyme
oncogenic ras inhibits anoikis of intestinal epithelial cells by preventing the release of a mitochondrial pro-apoptotic protein omi/htra2 into the cytoplasm
functional roles of p12, the fourth subunit of human dna polymerase
the active conformation of avilamycin a is conferred by avix12, a radical adomet enzyme
auto-activation of the apoptosis protein bax increases mitochondrial membrane permeability and is inhibited by bcl-2
equimolar production of amyloid -protein and amyloid precursor protein intracellular domain from -carboxyl-terminal fragment by -secretase
structural diversity in p160/creb-binding protein coactivator complexes
the structural basis of substrate promiscuity in glucose dehydrogenase from the hyperthermophilic archaeon sulfolobus solfataricus
pex19p binds pex30p and pex32p at regions required for their peroxisomal localization but separate from their peroxisomal targeting signals
the morphogenic properties of oligomeric endostatin are dependent on cell surface heparan sulfate
snare complex zero layer residues are not critical for n-ethylmaleimide-sensitive factor-mediated disassembly
differential targets and subcellular localization of antitumor alkyl-lysophospholipid in leukemic versus solid tumor cells
glycogen synthase kinase-3 inhibits the xenobiotic and antioxidant cell response by direct phosphorylation and nuclear exclusion of the transcription factor nrf2
a region in urokinase plasminogen receptor domain iii controlling a functional association with 51 integrin and tumor growth
simultaneous monitoring of ionophore- and inhibitor-mediated plasma and mitochondrial membrane potential changes in cultured neurons
mechanism of cl- selection by a glutamate-gated chloride (glucl) receptor revealed through mutations in the selectivity filter
p204 protein overcomes the inhibition of the differentiation of p19 murine embryonal carcinoma cells to beating cardiac myocytes by id proteins
major histocompatibility complex and t cell interactions of a universal t cell epitope from plasmodium falciparum circumsporozoite protein
the x-ray crystal structures of human -phosphomannomutase 1 reveal the structural basis of congenital disorder of glycosylation type 1a
stopped-flow kinetic analysis of eif4e and phosphorylated eif4e binding to cap analogs and capped oligoribonucleotides
membrane association, mechanism of action, and structure of arabidopsis embryonic factor 1 (fac1)
deoxycholic acid induces intracellular signaling through membrane perturbations
the specific fkbp38 inhibitor n-(n‘,n‘-dimethylcarboxamidomethyl)cycloheximide has potent neuroprotective and neurotrophic properties in brain ischemia
up-regulation of microglial cd11b expression by nitric oxide
plasticity in the composition of the light harvesting antenna of higher plants preserves structural integrity and biological function
crystal structure of type-iii geranylgeranyl pyrophosphate synthase from saccharomyces cerevisiae and the mechanism of product chain length determination
cpg dna-mediated induction of acute liver injury in d-galactosamine-sensitized mice
a novel pregnane x receptor-mediated and sterol regulatory element-binding protein-independent lipogenic pathway
a second nitrogenase-like enzyme for bacteriochlorophyll biosynthesis
methylation-independent binding to histone h3 and cell cycle-dependent incorporation of hp1 into heterochromatin
hsp90 recognizes a common surface on client kinases
double-stranded rna is internalized by scavenger receptor-mediated endocytosis in drosophila s2 cells
comparative peptide binding studies of the pabc domains from the ubiquitin-protein isopeptide ligase hyd and poly(a)-binding protein
multifunctional glyceraldehyde-3-phosphate dehydrogenase of streptococcus pyogenes is essential for evasion from neutrophils
cloning and recombinant expression of active full-length xylosyltransferase i (xt-i) and characterization of subcellular localization of xt-i and xt-ii
mldp, a novel pat family protein localized to lipid droplets and enriched in the heart, is regulated by peroxisome proliferator-activated receptor
dimeric and monomeric organization of photosystem ii
in vivo complementation of complex i by the yeast ndi1 enzyme
modular structure of the receptor binding proteins of lactococcus lactis phages
a novel ded1-like rna helicase interacts with the y-box protein ctyb-1 in nuclear mrnp particles and in polysomes
mechanism of a hereditary cataract phenotype
glycans on secretory component participate in innate protection against mucosal pathogens
posttranslational n-myristoylation is required for the anti-apoptotic activity of human tgelsolin, the c-terminal caspase cleavage product of human gelsolin
identification of two trna thiolation genes required for cell growth at extremely high temperatures
the valosin-containing protein (vcp) is a target of akt signaling required for cell survival
suppression of apoptosis by cyclophilin d via stabilization of hexokinase ii mitochondrial binding in cancer cells
mapping the principal interaction site of the brf1 and bdp1 subunits of saccharomyces cerevisiae tfiiib
gas1 is related to the glial cell-derived neurotrophic factor family receptors and regulates ret signaling
the sliding clamp binds to multiple sites within mutl and muts
caspase-3 cleaves and inactivates the glutamate transporter eaat2
clathrin-mediated endocytosis of the epithelial sodium channel
-selenoconotoxins, a new class of potent 7 neuronal nicotinic receptor antagonists
the coxsackievirus 2b protein increases efflux of ions from the endoplasmic reticulum and golgi, thereby inhibiting protein trafficking through the golgi
neuron-derived d-serine release provides a novel means to activate n-methyl-d-aspartate receptors
cross-linking of c-terminal residues of phospholamban to the ca2+ pump of cardiac sarcoplasmic reticulum to probe spatial and functional interactions within the tra..
nitric-oxide synthase output state
several acidic amino acids in the n-domain of insulin-like growth factor-binding protein-5 are important for its transactivation activity
alkylamides from echinacea are a new class of cannabinomimetics
quaternary ammonium compounds as water channel blockers
an extracellular pathway for dystroglycan function in acetylcholine receptor aggregation and laminin deposition in skeletal myotubes
the sox2 regulatory region 2 functions as a neural stem cell-specific enhancer in the telencephalon
glut1 deficiency links nutrient availability and apoptosis during embryonic development
modification of human immunodeficiency virus type 1 reverse transcriptase to target cells with elevated cellular dntp concentrations
the structure of the extracellular domain of triggering receptor expressed on myeloid cells like transcript-1 and evidence for a naturally occurring soluble fragment
cullin 4a-mediated proteolysis of ddb2 protein at dna damage sites regulates in vivo lesion recognition by xpc
crystal structure and nonhomologous end-joining function of the ligase component of mycobacterium dna ligase d
residues tyr253 and glu255 in strand 3 of -sheet c of antithrombin are key determinants of an exosite made accessible by heparin activation to promote rapid inhibit..
dynamics of carbon monoxide binding to cystathionine -synthase
the conserved glutamate (glu136) in transmembrane domain 2 of the serotonin transporter is required for the conformational switch in the transport cycle
the ns5a protein of the hepatitis c virus genotype 1a is cleaved by caspases to produce c-terminal-truncated forms of the protein that reside mainly in the cytosol
serotonin catabolism and the formation and fate of 5-hydroxyindole thiazolidine carboxylic acid
increased ca2+ affinity of cardiac thin filaments reconstituted with cardiomyopathy-related mutant cardiac troponin i
determination of the amino acids in yeast ribosomal protein ys11 essential for the recognition of nucleotides in 18 s ribosomal rna
the regulatory roles of the galactose permease and kinase in the induction response of the gal network in saccharomyces cerevisiae
characterization of a bicyclic peptide neuropilin-1 (np-1) antagonist (eg3287) reveals importance of vascular endothelial growth factor exon 8 for np-1 binding and ..
antiangiogenic effect of rosiglitazone is mediated via peroxisome proliferator-activated receptor -activated maxi-k channel opening in human umbilical vein endothel..
vhr1p, a new transcription factor from budding yeast, regulates biotin-dependent expression of vht1 and bio5
human keratinocytes acquire cellular cytotoxicity under uv-b irradiation
conversion of the low affinity ouabain-binding site of non-gastric h,k-atpase into a high affinity binding site by substitution of only five amino acids
release of hypoacetylated and trimethylated histone h4 is an epigenetic marker of early apoptosis
histone deacetylase 3 (hdac3) and other class i hdacs regulate colon cell maturation and p21 expression and are deregulated in human colon cancer
the interaction between cytoplasmic prion protein and the hydrophobic lipid core of membrane correlates with neurotoxicity
p53 is cleaved by caspases generating fragments localizing to mitochondria
bmp4 regulates pancreatic progenitor cell expansion through id2
mechanisms of the copper-dependent turnover of the copper chaperone for superoxide dismutase
trpc3 and trpc4 associate to form a redox-sensitive cation channel
kinetic analysis of the ku-dna binding activity reveals a redox-dependent alteration in protein structure that stimulates dissociation of the ku-dna complex
identification of t-cadherin as a novel target of dna methyltransferase 3b and its role in the suppression of nerve growth factor-mediated neurite outgrowth in pc12..
histone deacetylase inhibitors repress the transactivation potential of hypoxia-inducible factors independently of direct acetylation of hif-
molecular cloning and functional characterization of a cell-permeable superoxide dismutase targeted to lung adenocarcinoma cells
mutations affecting -tubulin folding and degradation
involvement of a putative [fe-s]-cluster-binding protein in the biogenesis of quinohemoprotein amine dehydrogenase
key role of src kinase in s100b-induced activation of the receptor for advanced glycation end products in vascular smooth muscle cells
sorla signaling by regulated intramembrane proteolysis
nitric oxide inhibits peroxidase activity of cytochrome c· cardiolipin complex and blocks cardiolipin oxidation
parathyroid hormone-related protein regulates tumor-relevant genes in breast cancer cells
transcription factor nrf2 protects hepg2 cells against cyp2e1 plus arachidonic acid-dependent toxicity
characterization of the interaction between the j-protein jac1p and the scaffold for fe-s cluster biogenesis, isu1p
organization and assembly of metal-thiolate clusters in epithelium-specific metallothionein-4
protein kinase c signaling inhibits cyclin d1 translation in intestinal epithelial cells
protein-membrane interaction and fatty acid transfer from intestinal fatty acid-binding protein to membranes
mitochondrial membrane potential is dependent on the oligomeric state of f1f0-atp synthase supracomplexes
sequence-specific interactions of nascent escherichia coli polypeptides with trigger factor and signal recognition particle
copper-dependent interaction of dynactin subunit p62 with the n terminus of atp7b but not atp7a
integrin receptor activation triggers converging regulation of cav1.2 calcium channels by c-src and protein kinase a pathways
hyaluronan-cd44 interaction with leukemia-associated rhogef and epidermal growth factor receptor promotes rho/ras co-activation, phospholipase c-ca2+ signaling, and..
deregulated activation of oncoprotein kinase tpl2/cot in htlv-i-transformed t cells
staphylococcus aureus operates protein-tyrosine phosphorylation through a specific mechanism
metabolite of sir2 reaction modulates trpm2 ion channel
mediator is a transducer of wnt/-catenin signaling
characterization of the molecular basis of the drosophila mutations in carboxypeptidase d
molecular models for murine sperm-egg binding
cernunnos interacts with the xrcc4·dna-ligase iv complex and is homologous to the yeast nonhomologous end-joining factor nej1
a double holliday junction dissolvasome comprising blm, topoisomerase iii, and blap75
tandemly activated trnas as participants in protein synthesis
rev3 and rev1 play major roles in recombination-independent repair of dna interstrand cross-links mediated by monoubiquitinated proliferating cell nuclear antigen (..
substrate specificity and structure-function analysis of the 3‘-phosphoesterase component of the bacterial nhej protein, dna ligase d
ucp1 and defense against oxidative stress
only one protomer is active in the dimer of sars 3c-like proteinase
hcell is the major e- and l-selectin ligand expressed on ls174t colon carcinoma cells
role of gsh in estrone sulfate binding and translocation by the multidrug resistance protein 1 (mrp1/abcc1)
ndr2 acts as the upstream kinase of ark5 during insulin-like growth factor-1 signaling
a1 subunit-mediated regulation of thrombin-activated factor viii a2 subunit dissociation
interaction of lipoprotein lipase and receptor-associated protein
aprataxin forms a discrete branch in the hit (histidine triad) superfamily of proteins with both dna/rna binding and nucleotide hydrolase activities
kinetic mechanism of akt/pkb enzyme family
hypoxic regulation of vascular endothelial growth factor through the induction of phosphatidylinositol 3-kinase/rho/rock and c-myc
interactions of tumor necrosis factor (tnf) and tnf receptor family members in the mouse and human
ycdb from escherichia coli reveals a novel class of tat-dependently translocated hemoproteins
depletion of udp-d-apiose/udp-d-xylose synthases results in rhamnogalacturonan-ii deficiency, cell wall thickening, and cell death in higher plants
involvement of topoisomerase iii in telomere-telomere recombination
rac1, but not rac1b, stimulates relb-mediated gene transcription in colorectal cancer cells
characterization of a megakaryocyte-specific enhancer of the key hemopoietic transcription factor gata1
regulation and function of skap-55 non-canonical motif binding to the sh3c domain of adhesion and degranulation-promoting adaptor protein
structure of the mouse peptide n-glycanase-hr23 complex suggests co-evolution of the endoplasmic reticulum-associated degradation and dna repair pathways
the crystal structures of dihydropyrimidinases reaffirm the close relationship between cyclic amidohydrolases and explain their substrate specificity
mitochondrial atp synthase
novel tumor necrosis factor-responsive mammalian neutral sphingomyelinase-3 is a c-tail-anchored protein
substrate localization creates specificity in calcium/calmodulin-dependent protein kinase ii signaling at synapses
prosap-interacting protein 1 (prosapip1), a novel protein of the postsynaptic density that links the spine-associated rap-gap (spar) to the scaffolding protein pros..
asf1 is required for viability and chromatin assembly during dna replication in vertebrate cells
amyloid fibrils of mammalian prion protein are highly toxic to cultured cells and primary neurons
autophosphorylation of akt at threonine 72 and serine 24
activation and cross-talk between akt, nf-b, and unfolded protein response signaling in 1-ln prostate cancer cells consequent to ligation of cell surface-associated..
mouse cristin/r-spondin family proteins are novel ligands for the frizzled 8 and lrp6 receptors and activate -catenin-dependent gene expression
a complete domain structure of drosophila tolloid is required for cleavage of short gastrulation
down-regulation of eukaryotic nitrate transporter by nitrogen-dependent ubiquitinylation
the proinflammatory actions of angiotensin ii are dependent on p65 phosphorylation by the ib kinase complex
syndapin oligomers interconnect the machineries for endocytic vesicle formation and actin polymerization
arno through its coiled-coil domain regulates endocytosis at the apical surface of polarized epithelial cells
perturbation of rrna synthesis in the bap28 mutation leads to apoptosis mediated by p53 in the zebrafish central nervous system
the role of decay-accelerating factor as a receptor for helicobacter pylori and a mediator of gastric inflammation
crystal structure of the biglycan dimer and evidence that dimerization is essential for folding and stability of class i small leucine-rich repeat proteoglycans
structural and functional variations in human apolipoprotein e3 and e4
the role of invariant amino acid residues at the hydride transfer site of proton-translocating transhydrogenase
assembly, activation, and trafficking of the fet3p·ftr1p high affinity iron permease complex in saccharomyces cerevisiae
rhoa/rock signaling regulates chondrogenesis in a context-dependent manner
rosiglitazone controls fatty acid cycling in human adipose tissue by means of glyceroneogenesis and glycerol phosphorylation
tid1 isoforms are mitochondrial dnaj-like chaperones with unique carboxyl termini that determine cytosolic fate
direct and indirect roles of cytochrome b in the mediation of superoxide generation and no catabolism by mitochondrial succinate-cytochrome c reductase
interacting jnk-docking sites in mkk7 promote binding and activation of jnk mitogen-activated protein kinases
-oxidation of very long-chain fatty acids in human liver microsomes
cell cycle- and apoptosis-regulatory protein-1 is involved in apoptosis signaling by epidermal growth factor receptor
molecular pharmacological phenotyping of ebi
a novel function of angiotensin ii in skin wound healing
deoxyhypusine hydroxylase is an fe(ii)-dependent, heat-repeat enzyme
allosteric activation of the follicle-stimulating hormone (fsh) receptor by selective, nonpeptide agonists
evolutional design of a hyperactive cysteine- and methionine-free mutant of escherichia coli dihydrofolate reductase
epithelial cells are sensitive detectors of bacterial pore-forming toxins
thioredoxin reductase 1 deficiency reverses tumor phenotype and tumorigenicity of lung carcinoma cells
aggrecan turnover in human intervertebral disc as determined by the racemization of aspartic acid
essential role of ubiquitin-proteasome system in normal regulation of insulin secretion
functional relevance of urinary-type plasminogen activator receptor-31 integrin association in proteinase regulatory pathways
silencing the activity and proliferative properties of the human eagi potassium channel by rna interference
cell-cell interaction-dependent regulation of n-acetylglucosaminyltransferase iii and the bisected n-glycans in ge11 epithelial cells
brca1 plays a role in the hypoxic response by regulating hif-1 stability and by modulating vascular endothelial growth factor expression
critical role of phospholipase c1 in the generation of h2o2-evoked [ca2+]i oscillations in cultured rat cortical astrocytes
analogs of insulin-like peptide 3 (insl3) b-chain are lgr8 antagonists in vitro and in vivo
tax-dependent displacement of nucleosomes during transcriptional activation of human t-cell leukemia virus type 1
the critical roles of polyamines in regulating cole7 production and restricting cole7 uptake of the colicin-producing escherichia coli
17-estradiol protects against oxidative stress-induced cell death through the glutathione/glutaredoxin-dependent redox regulation of akt in myocardiac h9c2 cells
low affinity analogs of thyrotropin-releasing hormone are super-agonists
regulation of the saccharomyces cerevisiae eki1-encoded ethanolamine kinase by zinc depletion
chemical modification of santonin into a diacetoxy acetal form confers the ability to induce differentiation of human promyelocytic leukemia cells via the down-regu..
nuclear factor-1-x regulates astrocyte-specific expression of the 1-antichymotrypsin and glial fibrillary acidic protein genes
effects of peripheral cannabinoid receptor ligands on motility and polarization in neutrophil-like hl60 cells and human neutrophils
crystal structure of prephenate dehydrogenase from aquifex aeolicus
an n-terminal sequence targets and tethers na+ pump 2 subunits to specialized plasma membrane microdomains
chronic antidepressants potentiate via sigma-1 receptors the brain-derived neurotrophic factor-induced signaling for glutamate release
leptin increases axonal growth cone size in developing mouse cortical neurons by convergent signals inactivating glycogen synthase kinase-3
extended polyglutamine tracts cause aggregation and structural perturbation of an adjacent barrel protein
complementation of one reca protein point mutation by another
contrasting effects of ewi proteins, integrins, and protein palmitoylation on cell surface cd9 organization
the mrh protein erlectin is a member of the endoplasmic reticulum synexpression group and functions in n-glycan recognition
a phage display screen and binding studies with acetylated low density lipoprotein provide evidence for the importance of the scavenger receptor cysteine-rich (srcr..
null mutations in drosophila n-acetylglucosaminyltransferase i produce defects in locomotion and a reduced life span
stabilization of plakoglobin and enhanced keratinocyte cell-cell adhesion by intracellular o-glycosylation
peptide agonist docking in the n-terminal ectodomain of a class ii g protein-coupled receptor, the vpac1 receptor
24(s)-hydroxycholesterol participates in a liver x receptor-controlled pathway in astrocytes that regulates apolipoprotein e-mediated cholesterol efflux
parkin protects against mitochondrial toxins and -amyloid accumulation in skeletal muscle cells
the dynamin-like protein vps1p of the yeast saccharomyces cerevisiae associates with peroxisomes in a pex19p-dependent manner
substrate profiling of cysteine proteases using a combinatorial peptide library identifies functionally unique specificities
topography of the surface of the signal-transducing protein eiiaglc that interacts with the malk subunits of the maltose atp-binding cassette transporter (malfgk2) ..
calreticulin negatively regulates the cell surface expression of cystic fibrosis transmembrane conductance regulator
three hrdc domains differentially modulate deinococcus radiodurans recq dna helicase biochemical activity
the s4-s5 linker directly couples voltage sensor movement to the activation gate in the human ether-á-go-go-related gene (herg) k+ channel
expression cloning of three rhizobium leguminosarum lipopolysaccharide core galacturonosyltransferases
dodecaprenyl phosphate-galacturonic acid as a donor substrate for lipopolysaccharide core glycosylation in rhizobium leguminosarum
murine model of the ehlers-danlos syndrome
characterization of the residues in helix 8 of the human 1-adrenergic receptor that are involved in coupling the receptor to g proteins
molecular dynamics simulations of the ligand-binding domain of an n-methyl-d-aspartate receptor
human tissue kallikrein 5 is a member of a proteolytic cascade pathway involved in seminal clot liquefaction and potentially in prostate cancer progression
posttranslational cleavage and adaptor protein complex-dependent trafficking of mucolipin-1
a trans-tail histone code defined by monomethylated h4 lys-20 and h3 lys-9 demarcates distinct regions of silent chromatin
fox-2 splicing factor binds to a conserved intron motif to promote inclusion of protein 4.1r alternative exon 16
loss of acinus inhibits oligonucleosomal dna fragmentation but not chromatin condensation during apoptosis
cell-surface processing of pro-adamts9 by furin
transcriptional repression of human immunodeficiency virus type 1 by ap-4
design of a long acting peptide functioning as both a glucagon-like peptide-1 receptor agonist and a glucagon receptor antagonist
single chain antibody displays glutathione s-transferase activity
the kinases msk1 and msk2 are required for epidermal growth factor-induced, but not tumor necrosis factor-induced, histone h3 ser10 phosphorylation
membrane-catalyzed nucleotide exchange on dnaa
novel dna binding by a basic helix-loop-helix protein
characterization of the mechanism of cytochrome p450 reductase-cytochrome p450-mediated nitric oxide and nitrosothiol generation from organic nitrates
novel peptide inhibitors of human kallikrein 2
the nh2-terminal php domain of the subunit of the escherichia coli replicase binds the proofreading subunit
ligand-induced effects on pyruvate dehydrogenase kinase isoform 2
sodium butyrate ameliorates histone hypoacetylation and neurodegenerative phenotypes in a mouse model for drpla
transgenic drak2 overexpression in mice leads to increased t cell apoptosis and compromised memory t cell development
thermodynamic analysis reveals structural rearrangement during the acylation step in human trypsin 4 on 4-methylumbelliferyl 4-guanidinobenzoate substrate analogue
mutation of a critical arginine in the gtp-binding site of transglutaminase 2 disinhibits intracellular cross-linking activity
on the relationship of coral allene oxide synthase to catalase
the ubiquitin isopeptidase ubpy regulates endosomal ubiquitin dynamics and is essential for receptor down-regulation
association of rna helicase a with human immunodeficiency virus type 1 particles
direct binding of translation initiation factor eif2-g domain to its gtpase-activating and gdp-gtp exchange factors eif5 and eif2b
a novel member of the ib family, human ib-, inhibits transactivation of p65 and its dna binding
escherichia coli recq is a rapid, efficient, and monomeric helicase
btb domain-containing speckle-type poz protein (spop) serves as an adaptor of daxx for ubiquitination by cul3-based ubiquitin ligase
peroxisome proliferator-activated receptor -mediated regulation of neural stem cell proliferation and differentiation
adipose tissue proadipogenic redox changes in obesity
structural and molecular interactions of ccr5 inhibitors with ccr5
the crystal structure of h-2db complexed with a partial peptide epitope suggests a major histocompatibility complex class i assembly intermediate
pax2 activates wnt4 expression during mammalian kidney development
molecular characterization of a novel udp-galactose:fucoside 3-galactosyltransferase that modifies skp1 in the cytoplasm of dictyostelium
nuclear factor-b activated by capacitative ca2+ entry enhances muscarinic receptor-mediated soluble amyloid precursor protein (sapp) release in sh-sy5y cells
membrane fusion by single influenza hemagglutinin trimers
mutations in the dimerization domain of the b subunit from the escherichia coli atp synthase
syntrophins regulate 1d-adrenergic receptors through a pdz domain-mediated interaction
the cgmp/protein kinase g pathway contributes to dihydropyridine-sensitive calcium response and cytokine production in th2 lymphocytes
dna replication in protein extracts from human cells requires orc and mcm proteins
the role of the dif motif of the dnaj (hsp40) co-chaperone in the regulation of the dnak (hsp70) chaperone cycle
a novel protein geranylgeranyltransferase-i inhibitor with high potency, selectivity, and cellular activity
cell type-specific differential induction of the human -fibrinogen promoter by interleukin-6
aminopeptidase n (cd13) regulates tumor necrosis factor--induced apoptosis in human neutrophils
interaction of protein inhibitor of activated stat (pias) proteins with the tata-binding protein, tbp
the p174l mutation in human sco1 severely compromises cox17-dependent metallation but does not impair copper binding
anion channels, including clc-3, are required for normal neutrophil oxidative function, phagocytosis, and transendothelial migration
hiv-1 gp120-mediated apoptosis of t cells is regulated by the membrane tyrosine phosphatase cd45
corynebacterial protein kinase g controls 2-oxoglutarate dehydrogenase activity via the phosphorylation status of the odhi protein
hap4 is not essential for activation of respiration at low specific growth rates in saccharomyces cerevisiae
kinetic evidence for inefficient and error-prone bypass across bulky n2-guanine dna adducts by human dna polymerase
functional analysis of the purified anandamide-generating phospholipase d as a member of the metallo--lactamase family
a metabotropic glutamate receptor family gene in dictyostelium discoideum
roles of the mammalian cytosolic cysteine desulfurase, iscs, and scaffold protein, iscu, in iron-sulfur cluster assembly
role of the arf6 gdp/gtp cycle and arf6 gtpase-activating proteins in actin remodeling and intracellular transport
a consensus adenine at position -11 of the nontemplate strand of bacterial promoter is important for nucleation of promoter melting
dna cleavage of a cryptic recombination signal sequence by rag1 and rag
biotin sensing in saccharomyces cerevisiae is mediated by a conserved dna element and requires the activity of biotin-protein ligase
differential contributions of motilin receptor extracellular domains for peptide and non-peptidyl agonist binding and activity
migfilin interacts with vasodilator-stimulated phosphoprotein (vasp) and regulates vasp localization to cell-matrix adhesions and migration
transfer rna cleavages by onconase reveal unusual cleavage sites
nfat induces breast cancer cell invasion by promoting the induction of cyclooxygenase-2
nuclear import of ho endonuclease utilizes two nuclear localization signals and four importins of the ribosomal import system
manganese is the link between frataxin and iron-sulfur deficiency in the yeast model of friedreich ataxia
negative regulation of lrp6 function by casein kinase i phosphorylation
role of gac63 in transcriptional activation mediated by the aryl hydrocarbon receptor
subunit a of cytochrome o oxidase requires both yidc and secyeg for membrane insertion
down-regulation of porins by a small rna bypasses the essentiality of the regulated intramembrane proteolysis protease rsep in escherichia coli
an interaction between insulin-like growth factor-binding protein 2 (igfbp2) and integrin 5 is essential for igfbp2-induced cell mobility
formation of f-ring isoprostane-like compounds (f3-isoprostanes) in vivo from eicosapentaenoic acid
redox-dependent matrix metalloproteinase-1 expression is regulated by jnk through ets and ap-1 promoter motifs
role of stat3 in type i interferon responses
quantitative analysis of in vivo initiator selection by yeast rna polymerase ii supports a scanning model
ubiquitination of rip is required for tumor necrosis factor -induced nf-b activation
physical and functional association of glucuronyltransferases and sulfotransferase involved in hnk-1 biosynthesis
the cytoplasmic heme-binding protein (phus) from the heme uptake system of pseudomonas aeruginosa is an intracellular heme-trafficking protein to the -regioselectiv..
the stability and anti-apoptotic function of a1 are controlled by its c terminus
functional inhibitory cross-talk between constitutive androstane receptor and hepatic nuclear factor-4 in hepatic lipid/glucose metabolism is mediated by competitio..
p204 is required for the differentiation of p19 murine embryonal carcinoma cells to beating cardiac myocytes
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