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生物物理学杂志2006年第01期封面 购买


endotoxin (lipopolysaccharide) neutralization by innate immunity host-defense peptides
structural determinants for the binding of anthrax lethal factor to oligomeric protective antigen
thermodynamics of -catenin-ligand interactions
a splice variant of stress response gene atf3 counteracts nf-b-dependent anti-apoptosis through inhibiting recruitment of creb-binding protein/p300 coactivator
study of highly constitutively active mutants suggests how camp activates camp receptor protein
soluble interleukin-15 receptor (il-15r)-sushi as a selective and potent agonist of il-15 action through il-15r/
direct comparison of a stable isolated hsp70 substrate-binding domain in the empty and substrate-bound states
adult tissue-specific expression of a dppa3-derived retrogene represents a postnatal transcript of pluripotent cell origin
temporal profile of amyloid- (a) oligomerization in an in vivo model of alzheimer disease
identification of a switch in neurotrophin signaling by selective tyrosine phosphorylation
the cis-regulatory element gsl5 is indispensable for proximal straight tubule cell-specific transcription of core 2 -1,6-n-acetylglucosaminyltransferase in the mous..
a c-terminal domain in kcc2 confers constitutive k+-cl- cotransport
ephb receptors regulate dendritic spine morphogenesis through the recruitment/phosphorylation of focal adhesion kinase and rhoa activation
human trpv4 channel splice variants revealed a key role of ankyrin domains in multimerization and trafficking
formation of a distinctive complex between the inducible bacterial lysine decarboxylase and a novel aaa+ atpase
transfer and tunneling of ca2+ from sarcoplasmic reticulum to mitochondria in skeletal muscle
adamts13 substrate recognition of von willebrand factor a2 domain
protein kinase b/akt is a novel cysteine string protein kinase that regulates exocytosis release kinetics and quantal size
molecular architecture and ligand recognition determinants for t4 rna ligase
channel properties of tpsb transporter fhac point to two functional domains with a c-terminal protein-conducting pore
identification of the mitochondrial nad+ transporter in saccharomyces cerevisiae
interleukin-1 induction of nfb is partially regulated by h2o2-mediated activation of nfb-inducing kinase
phosphorylation of ib- is necessary for neuronal survival
subcellular targeting and differential s-nitrosylation of endothelial nitric-oxide synthase
a soluble pyrophosphatase, a key enzyme for polyphosphate metabolism in leishmania
mast cell and neutrophil peptidases attack an inactivation segment in hepatocyte growth factor to generate nk4-like antagonists
the first glycosynthase derived from an inverting glycoside hydrolase
estrogen receptor- mediates gender differences in atherosclerosis induced by hiv protease inhibitors
mechanical inhibition of rankl expression is regulated by h-ras-gtpase
a competitive mechanism for staphylococcal toxin ssl7 inhibiting the leukocyte iga receptor, fcri, is revealed by ssl7 binding at the c2/c3 interface of iga
charge modification at multiple c-terminal lysine residues regulates p53 oligomerization and its nucleus-cytoplasm trafficking
presenilin-1 interacts with plakoglobin and enhances plakoglobin-tcf-4 association
glutamic acid-rich proteins of rod photoreceptors are natively unfolded
distinct pathways regulate proapoptotic nix and bnip3 in cardiac stress
substrate distortion in the michaelis complex of bacillus 1,3-1,4--glucanase
characterization of an aldolase-binding site in the wiskott-aldrich syndrome protein
differences in enos activity because of subcellular localization are dictated by phosphorylation state rather than the local calcium environment
structure of the pyrroloquinoline quinone radical in quinoprotein ethanol dehydrogenase
shank2 associates with and regulates na+/h+ exchanger 3
psbr, a missing link in the assembly of the oxygen-evolving complex of plant photosystem ii
the wnt-inducible transcription factor twist1 inhibits chondrogenesis
the tyrosine kinase syk regulates tpl2 activation signals
polycystin-2 regulates proliferation and branching morphogenesis in kidney epithelial cells
rna polymerase ii blockage by cisplatin-damaged dna
centaurin-1 is a phosphatidylinositol 3-kinase-dependent activator of erk1/2 mitogen-activated protein kinases
the virulence-associated two-component phop-phor system controls the biosynthesis of polyketide-derived lipids in mycobacterium tuberculosis
regulation through the rna polymerase secondary channel
a structural perspective on enzymes activated by monovalent cations
structure and carboxyl-terminal domain (ctd) binding of the set2 sri domain that couples histone h3 lys36 methylation to transcription
caspases target only two architectural components within the core structure of the nuclear pore complex
mutations in the peroxin pex26p responsible for peroxisome biogenesis disorders of complementation group 8 impair its stability, peroxisomal localization, and inter..
arachidonic acid regulates the translocation of 5-lipoxygenase to the nuclear membranes in human neutrophils
molecular analysis of survivin isoforms
mcp-1-induced human osteoclast-like cells are tartrate-resistant acid phosphatase, nfatc1, and calcitonin receptor-positive but require receptor activator of nfb li..
-arrestin-dependent, g protein-independent erk1/2 activation by the 2 adrenergic receptor
membrane topology of mouse stearoyl-coa desaturase 1
altered hiv-1 gag protein interactions with cyclophilin a (cypa) on the acquisition of h219q and h219p substitutions in the cypa binding loop
mechanism of uptake of c105y, a novel cell-penetrating peptide
crystal structure of an archaeal pentameric riboflavin synthase in complex with a substrate analog inhibitor
the guanine nucleotide exchange factor cnrasgef regulates melanogenesis and cell survival in melanoma cells
regulation of transactivation function of the aryl hydrocarbon receptor by the epstein-barr virus-encoded ebna-3 protein
inducible expression of tau repeat domain in cell models of tauopathy
identification of a lipid peroxidation product as a potential trigger of the p53 pathway
exendin-4 uses irs2 signaling to mediate pancreatic cell growth and function
novel fluorescent prothrombin analogs as probes of staphylocoagulase-prothrombin interactions
fibrinogen substrate recognition by staphylocoagulase·(pro)thrombin complexes
structural basis for reduced staphylocoagulase-mediated bovine prothrombin activation
chemical blockage of the proteasome inhibitory function of bortezomib
rab7 activity affects epidermal growth factor:epidermal growth factor receptor degradation by regulating endocytic trafficking from the late endosome
the forkhead transcription factor foxo1 bridges the jnk pathway and the transcription factor pdx-1 through its intracellular translocation
essential role of aralar in the transduction of small ca+ signals to neuronal mitochondria
deficiency of disulfide bonds facilitating fibrillogenesis of endostatin
the plant plasma membrane ca2+ pump aca8 contains overlapping as well as physically separated autoinhibitory and calmodulin-binding domains
binding of pai-1 to endothelial cells stimulated by thymosin 4 and modulation of their fibrinolytic potential
biochemical properties of human pantothenate kinase 2 isoforms and mutations linked to pantothenate kinase-associated neurodegeneration
model of biologically active apolipoprotein e bound to dipalmitoylphosphatidylcholine
distinct bir domains of ciap1 mediate binding to and ubiquitination of tumor necrosis factor receptor-associated factor 2 and second mitochondrial activator of casp..
glycosylation substrate specificity of pseudomonas aeruginosa 1244 pilin
function of positive charges following signal-anchor sequences during translocation of the n-terminal domain
c to u editing stimulates a to i editing in the anticodon loop of a cytoplasmic threonyl trna in trypanosoma brucei
the ftsh protease slr0228 is important for quality control of photosystem ii in the thylakoid membrane of synechocystis sp. pcc 6803
identification of the fibroblast growth factor (fgf)-interacting domain in a secreted fgf-binding protein by phage display
increased membrane affinity of the c1 domain of protein kinase c compensates for the lack of involvement of its c2 domain in membrane recruitment
localization of tlr2 and myd88 to chlamydia trachomatis inclusions
the second intracellular loop of the calcitonin gene-related peptide receptor provides molecular determinants for signal transduction and cell surface expression
overexpression of leucyl aminopeptidase in plasmodium falciparum parasites
vegf165-binding sites within heparan sulfate encompass two highly sulfated domains and can be liberated by k5 lyase
erbb1 functions as a sensor of airway epithelial integrity by regulation of protein phosphatase 2a activity
a pathway for tumor necrosis factor--induced bcl10 nuclear translocation
streptococcal protein fog, a novel matrix adhesin interacting with collagen i in vivo
identification and functional expression of a family of nicotinic acetylcholine receptor subunits in the central nervous system of the mollusc lymnaea stagnalis
dna replication stress-induced phosphorylation of cyclic amp response element-binding protein mediated by atm
characterization of a binary tandem domain f-type lectin from striped bass (morone saxatilis)
identification and characterization of amino acid residues essential for the active site of udp-n-acetylenolpyruvylglucosamine reductase (murb) from staphylococcus ..
phosphorylated -actinin and protein-tyrosine phosphatase 1b coregulate the disassembly of the focal adhesion kinase·src complex and promote cell migration
hic-5 is a novel repressor of lymphoid enhancer factor/t-cell factor-driven transcription
an arabidopsis fip1 homolog interacts with rna and provides conceptual links with a number of other polyadenylation factor subunits
rhoa modulates smad signaling during transforming growth factor--induced smooth muscle differentiation
pneumococcal -lactam resistance due to a conformational change in penicillin-binding protein 2x
the physical properties of the capsular polysaccharides from cryptococcus neoformans suggest features for capsule construction
differential inhibition of mrna degradation pathways by novel cap analogs
intrinsic protein disorder, amino acid composition, and histone terminal domains
opposite roles of fap-1 and dynamin in the regulation of fas (cd95) translocation to the cell surface and susceptibility to fas ligand-mediated apoptosis
g protein-induced trafficking of voltage-dependent calcium channels
staphylococcus aureus sortase a transpeptidase
the schizosaccharomyces pombe replication inhibitor spd1 regulates ribonucleotide reductase activity and dntps by binding to the large cdc22 subunit
y-box protein-1 is the crucial mediator of antifibrotic interferon- effects
regulation of sensory neuron-specific acid-sensing ion channel 3 by the adaptor protein na+/h+ exchanger regulatory factor-1
conversion of green fluorescent protein into a toxic, aggregation-prone protein by c-terminal addition of a short peptide
the heat shock protein 90-cdc37 chaperone complex is required for signaling by types i and ii interferons
effects of stable suppression of group via phospholipase a2 expression on phospholipid content and composition, insulin secretion, and proliferation of ins-1 insuli..
phosphorylation of p-rex1 by the cyclic amp-dependent protein kinase inhibits the phosphatidylinositiol (3,4,5)-trisphosphate and g-mediated regulation of its activ..
differential sensitivity of p-rex1 to isoforms of g protein dimers
mass spectrometric analysis of the ubiquinol-binding site in cytochrome bd from escherichia coli
genetic demonstration that the plasma membrane maxianion channel and voltage-dependent anion channels are unrelated proteins
alkaline-shifted pho sensitivity of ae2c1-mediated anion exchange reveals novel regulatory determinants in the ae2 n-terminal cytoplasmic domain
pheromone-regulated sumoylation of transcription factors that mediate the invasive to mating developmental switch in yeast
astrocyte-specific expression of the 1-antichymotrypsin and glial fibrillary acidic protein genes requires activator protein-1
sequence, distance, and accessibility are determinants of 5‘-end-directed cleavages by retroviral rnases h
function and evolution of a mosquito salivary protein family
heparan sulfate polymerization in drosophila
involvement of vertebrate pol in translesion dna synthesis across dna monoalkylation damage
an hgcn5/trrap histone acetyltransferase complex co-activates brca1 transactivation function through histone modification
hoxd13 and hoxa13 directly control the expression of the epha7 ephrin tyrosine kinase receptor in developing limbs
interleukin-8 secretion by fibroblasts induced by low density lipoproteins is p38 mapk-dependent and leads to cell spreading and wound closure
nitration of tyrosine 92 mediates the activation of rat microsomal glutathione s-transferase by peroxynitrite
e6ap and calmodulin reciprocally regulate estrogen receptor stability
differential sensitivity of the cystic fibrosis (cf)-associated mutants g551d and g1349d to potentiators of the cystic fibrosis transmembrane conductance regulator ..
proline oxidase, a proapoptotic gene, is induced by troglitazone
stress-induced response, localization, and regulation of the pmk1 cell integrity pathway in schizosaccharomyces pombe
cellular trafficking and degradation of erythropoietin and novel erythropoiesis stimulating protein (nesp)
tyr-95 and ile-172 in transmembrane segments 1 and 3 of human serotonin transporters interact to establish high affinity recognition of antidepressants
nod2/card15 mediates induction of the antimicrobial peptide human beta-defensin-2
effect of mg2+ on the dna binding modes of the streptococcus pneumoniae ssba and ssbb proteins
a thr357 to ser polymorphism in homozygous and compound heterozygous subjects causes absent or reduced p2x7 function and impairs atp-induced mycobacterial killing b..
stathmin strongly increases the minus end catastrophe frequency and induces rapid treadmilling of bovine brain microtubules at steady state in vitro
protein kinase a-mediated phosphorylation modulates cytochrome c oxidase function and augments hypoxia and myocardial ischemia-related injury
regulation of the interaction of inosine monophosphate dehydrogenase with mycophenolic acid by gtp
modulation of monocarboxylic acid transporter-1 kinetic function by the camp signaling pathway in rat brain endothelial cells
the role of properdin in the assembly of the alternative pathway c3 convertases of complement
tissue-type plasminogen activator acts as a cytokine that triggers intracellular signal transduction and induces matrix metalloproteinase-9 gene expression
on the mechanism of mitochondrial uncoupling protein 1 function
temperature-dependent biosynthesis of 2-thioribothymidine of thermus thermophilus trna
negative regulation of the retinoic acid-inducible gene i-induced antiviral state by the ubiquitin-editing protein a20
the c-terminal activating region 2 of the epstein-barr virus-encoded latent membrane protein 1 activates nf-b through traf6 and tak1
structural changes of region 1-16 of the alzheimer disease amyloid -peptide upon zinc binding and in vitro aging
periplasmic protein-protein contacts in the inner membrane protein wzc form a tetrameric complex required for the assembly of escherichia coli group 1 capsules
changes in cytosolic ca2+ levels regulate bcl-xs and bcl-xl expression in spermatogenic cells during apoptotic death
cardiomyopathy associated with microcirculation dysfunction in laminin 4 chain-deficient mice
protein-tyrosine phosphatase 1b deficiency protects against fas-induced hepatic failure
assembly of the bi-component leukocidin pore examined by truncation mutagenesis
role of the amino latch of staphylococcal -hemolysin in pore formation
base flipping in nucleotide excision repair
mdv1 interacts with assembled dnm1 to promote mitochondrial division
narj chaperone binds on two distinct sites of the aponitrate reductase of escherichia coli to coordinate molybdenum cofactor insertion and assembly
two isoforms of a divalent metal transporter (dmt1) in schistosoma mansoni suggest a surface-associated pathway for iron absorption in schistosomes
selective role of intracellular chloride in the regulation of the intrinsic but not extrinsic pathway of apoptosis in jurkat t-cells
paratope determination of the antithrombotic antibody 82d6a3 based on the crystal structure of its complex with the von willebrand factor a3-domain
regulation of p53 by activated protein kinase c- during nitric oxide-induced dopaminergic cell death
cysteine-disulfide cross-linking to monitor snare complex assembly during endoplasmic reticulum-golgi transport
mon2, a relative of large arf exchange factors, recruits dop1 to the golgi apparatus
interacting residues in an activated state of a g protein-coupled receptor
quantifying the specific binding between west nile virus envelope domain iii protein and the cellular receptor v3 integrin
rad3-cds1 mediates coupling of initiation of meiotic recombination with dna replication
inactivation of homocitrate synthase causes lysine auxotrophy in copper/zinc-containing superoxide dismutase-deficient yeast schizosaccharomyces pombe
reuptake of extracellular amelogenin by dental epithelial cells results in increased levels of amelogenin mrna through enhanced mrna stabilization
structure of chlorobium tepidum sepiapterin reductase complex reveals the novel substrate binding mode for stereospecific production of l-threo-tetrahydrobiopterin
toward a better understanding of the basis of the molecular mimicry of polysaccharide antigens by peptides
conformational dimorphism of self-peptides and molecular mimicry in a disease-associated hla-b27 subtype
suppression of rhoa activity by focal adhesion kinase-induced activation of p190rhogap
microtubule-associated protein map1a, map1b, and map2 proteolysis during soluble amyloid -peptide-induced neuronal apoptosis
functional evidence for a small and rigid active site in a high fidelity dna polymerase
annealing prion protein amyloid fibrils at high temperature results in extension of a proteinase k-resistant core
efficient and high fidelity incorporation of dctp opposite 7,8-dihydro-8-oxodeoxyguanosine by sulfolobus solfataricus dna polymerase dpo4
dna damage promotes histone deacetylase 4 nuclear localization and repression of g2/m promoters, via p53 c-terminal lysines
identification by mutational analysis of amino acid residues essential in the chaperone function of calreticulin
human sod1 before harboring the catalytic metal
crystal structure of the ferm domain of focal adhesion kinase
the loss of pin1 deregulates cyclin e and sensitizes mouse embryo fibroblasts to genomic instability
versican/pg-m regulates chondrogenesis as an extracellular matrix molecule crucial for mesenchymal condensation
analysis of nod2-mediated proteome response to muramyl dipeptide in hek293 cells
physical interaction and mutual transrepression between ccaat/enhancer-binding protein and the p53 tumor suppressor
the structure of dimeric rock i reveals the mechanism for ligand selectivity
the yeast arr4p atpase binds the chloride transporter gef1p when copper is available in the cytosol
cooperative actions of tra2 with 9g8 and srp30c in the rna splicing of the gonadotropin-releasing hormone gene transcript
characterization of rapidly degraded polypeptides in mammalian cells reveals a novel layer of nascent protein quality control
mechanistic and functional studies of the interaction of a proline-rich antimicrobial peptide with mammalian cells
functional human mitochondrial dna polymerase forms a heterotrimer
a role for kif17 in transport of kv4.2
in vitro transport of membrane proteins to peroxisomes by shuttling receptor pex19p
the structure of prp40 ff1 domain and its interaction with the crn-tpr1 motif of clf1 gives a new insight into the binding mode of ff domains
significance of sterol structural specificity
evidence that the 11 -hydroxysteroid dehydrogenase (11 -hsd1) is regulated by pentose pathway flux
familial parkinson mutant -synuclein causes dopamine neuron dysfunction in transgenic caenorhabditis elegans
mitochondrial transcription factor a induction by redox activation of nuclear respiratory factor 1
characterization of a defensin from the oyster crassostrea gigas
siah1 interacts with the scaffold protein posh to promote jnk activation and apoptosis
cross-talk between thyroid hormone receptor and liver x receptor regulatory pathways is revealed in a thyroid hormone resistance mouse model
g activation site in adenylyl cyclase type ii
orf17 from the clavulanic acid biosynthesis gene cluster catalyzes the atp-dependent formation of n-glycyl-clavaminic acid
decreased subunit stability as a novel mechanism for potassium current impairment by a kcnq2 c terminus mutation causing benign familial neonatal convulsions
fgfr4 is required for effective muscle regeneration in vivo
functional importance of three basic residues clustered at the cytosolic interface of transmembrane helix 15 in the multidrug and organic anion transporter mrp1 (ab..
obese yeast: triglyceride lipolysis is functionally conserved from mammals to yeast
glut4 distribution between the plasma membrane and the intracellular compartments is maintained by an insulin-modulated bipartite dynamic mechanism
the solvent protection of alzheimer amyloid--(1-42) fibrils as determined by solution nmr spectroscopy
retention of mutant low density lipoprotein receptor in endoplasmic reticulum (er) leads to er stress
integration requires a specific interaction of the donor dna terminal 5‘-cytosine with glutamine 148 of the hiv-1 integrase flexible loop
ferrous ions and reactive oxygen species increase antigen-binding and anti-inflammatory activities of immunoglobulin g
the plasma membrane ca2+-atpase isoform 4 is localized in lipid rafts of cerebellum synaptic plasma membranes
crystal structure of aqpz tetramer reveals two distinct arg-189 conformations associated with water permeation through the narrowest constriction of the water-condu..
biosensors to measure inositol 1,4,5-trisphosphate concentration in living cells with spatiotemporal resolution
shigella spa33 is an essential c-ring component of type iii secretion machinery
src activation is not necessary for transforming growth factor (tgf)--mediated epithelial to mesenchymal transitions (emt) in mammary epithelial cells
a structural and functional analysis of -glucan recognition by family 25 and 26 carbohydrate-binding modules reveals a conserved mode of starch recognition
structure of the human papillomavirus e7 oncoprotein and its mechanism for inactivation of the retinoblastoma tumor suppressor
the crystal structure of mismatch-specific uracil-dna glycosylase (mug) from deinococcus radiodurans reveals a novel catalytic residue and broad substrate specificity
expression patterns and post-translational modifications associated with mammalian histone h3 variants
focally elevated creatine detected in amyloid precursor protein (app) transgenic mice and alzheimer disease brain tissue
the role of the subunit in the escherichia coli atp synthase
molecular basis of the interaction between the flagellar export proteins flii and flih from helicobacter pylori
regulation of kiss-1 metastasis suppressor gene expression in breast cancer cells by direct interaction of transcription factors activator protein-2 and specificity..
functional analysis of the bacteriophage t4 dna-packaging atpase motor
intracellular versus cell surface assembly of retroviral pseudotypes is determined by the cellular localization of the viral glycoprotein, its capacity to interact ..
the rac activator tiam1 is a wnt-responsive gene that modifies intestinal tumor development
cell wall-targeting domain of glycylglycine endopeptidase distinguishes among peptidoglycan cross-bridges
the [fe-fe]-hydrogenase maturation protein hydf from thermotoga maritima is a gtpase with an iron-sulfur cluster
the f-box protein fbx4 targets pin2/trf1 for ubiquitin-mediated degradation and regulates telomere maintenance
extrasynaptic membrane trafficking regulated by glur1 serine 845 phosphorylation primes ampa receptors for long-term potentiation
chx10 targets a subset of photoreceptor genes
the flatworm spliced leader 3‘-terminal aug as a translation initiator methionine
functional characterization of dehydratase/aminotransferase pairs from helicobacter and campylobacter
trypsin cleaves acid-sensing ion channel 1a in a domain that is critical for channel gating
identification and characterization of a mammalian 39-kda poly(adp-ribose) glycohydrolase
control of myeov protein synthesis by upstream open reading frames
bcl-2 and mn-sod antisense oligodeoxynucleotides and a glutamine-enriched diet facilitate elimination of highly resistant b16 melanoma cells by tumor necrosis facto..
interaction of spin90 with the arp2/3 complex mediates lamellipodia and actin comet tail formation
increased proliferation and altered growth factor dependence of human mammary epithelial cells overexpressing the gab2 docking protein
the related retinoblastoma (prb) and p130 proteins cooperate to regulate homeostasis in the intestinal epithelium
how dihydrolipoamide dehydrogenase-binding protein binds dihydrolipoamide dehydrogenase in the human pyruvate dehydrogenase complex
glycosphingolipid-facilitated membrane insertion and internalization of cobra cardiotoxin
maximal activation of skeletal muscle thin filaments requires both rigor myosin s1 and calcium
metallothionein disulfides are present in metallothionein-overexpressing transgenic mouse heart and increase under conditions of oxidative stress
glycosylphosphatidylinositol-anchored proteases of candida albicans target proteins necessary for both cellular processes and host-pathogen interactions
hydrolysis of phosphatidylserine-exposing red blood cells by secretory phospholipase a2 generates lysophosphatidic acid and results in vascular dysfunction
phosphorylation of hsf1 by mapk-activated protein kinase 2 on serine 121, inhibits transcriptional activity and promotes hsp90 binding
role of transmembrane segment 10 in efflux mediated by the staphylococcal multidrug transport protein qaca
mediator as a general transcription factor
a splicing repressor domain in polypyrimidine tract-binding protein
regulation of 3-hydroxy-3-methylglutaryl coenzyme a reductase promoter by nuclear receptors liver receptor homologue-1 and small heterodimer partner
evidence that ser87 of bimel is phosphorylated by akt and regulates bimel apoptotic function
a novel o-aminophenol oxidase responsible for formation of the phenoxazinone chromophore of grixazone
g-protein-coupled ox1 orexin/hcrtr-1 hypocretin receptors induce caspase-dependent and -independent cell death through p38 mitogen-/stress-activated protein kinase
gerstmann-sträussler-scheinker disease amyloid protein polymerizes according to the “dock-and-lock“ model
cross-species vascular endothelial growth factor (vegf)-blocking antibodies completely inhibit the growth of human tumor xenografts and measure the contribution of ..
rat long chain acyl-coa synthetase 5 increases fatty acid uptake and partitioning to cellular triacylglycerol in mcardle-rh7777 cells
the fasting-induced adipose factor/angiopoietin-like protein 4 is physically associated with lipoproteins and governs plasma lipid levels and adiposity
erbin inhibits raf activation by disrupting the sur-8-ras-raf complex
cooperation of erk and scfskp2 for mkp-1 destruction provides a positive feedback regulation of proliferating signaling
zinc and calcium ions cooperatively modulate adamts13 activity
the retinoblastoma family proteins bind to and activate diacylglycerol kinase
a single amino acid substitution in the activation loop defines the decoy characteristic of vegfr-1/flt-1
domain architecture of protein-disulfide isomerase facilitates its dual role as an oxidase and an isomerase in ero1p-mediated disulfide formation
scanning the membrane-bound conformation of helix 1 in the colicin e1 channel domain by site-directed fluorescence labeling
dpm1, the catalytic subunit of dolichol-phosphate mannose synthase, is tethered to and stabilized on the endoplasmic reticulum membrane by dpm3
regulation of gli1 localization by the camp/protein kinase a signaling axis through a site near the nuclear localization signal
outer chain n-glycans are required for cell wall integrity and virulence of candida albicans
fibroblast growth factor-2 is a downstream mediator of phosphatidylinositol 3-kinase-akt signaling in 14,15-epoxyeicosatrienoic acid-induced angiogenesis
leu309 plays a critical role in the encapsulation of substrate protein into the internal cavity of groel
the streptococcal lipoprotein rotamase a (slra) is a functional peptidyl-prolyl isomerase involved in pneumococcal colonization
induction of oxidative metabolism by mitochondrial frataxin inhibits cancer growth
insulin enhances growth hormone induction of the mek/erk signaling pathway
estrogen-related receptor is a repressor of phosphoenolpyruvate carboxykinase gene transcription
scanning cysteine mutagenesis analysis of a-(1-40) amyloid fibrils
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