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a global regulatory role of gluconeogenic genes in escherichia coli revealed by transcriptome network analysis
unstructured conformations are a substrate requirement for the sir2 family of nad-dependent protein deacetylases
nucleo-cytoplasmic shuttling of high risk human papillomavirus e2 proteins induces apoptosis
cooperative phosphorylation of the tumor suppressor phosphatase and tensin homologue (pten) by casein kinases and glycogen synthase kinase 3
the translational efficiencies of the two leishmania infantum hsp70 mrnas, differing in their 3‘-untranslated regions, are affected by shifts in the temperature of..
the long terminal repeat (ltr) of erv-9 human endogenous retrovirus binds to nf-y in the assembly of an active ltr enhancer complex nf-y/mzf1/gata-2
substrate-induced conformational changes in the membrane-embedded iicmtl-domain of the mannitol permease from escherichia coli, enzymeiimtl, probed by tryptophan ph..
apoptosis-associated tyrosine kinase (aatyk) has differential ca2+-dependent phosphorylation states in response to survival and apoptotic conditions in cerebellar g..
binding of clostridium botulinum type c and d neurotoxins to ganglioside and phospholipid
fibrin but not adsorbed fibrinogen supports fibronectin assembly by spread platelets
suppression of death receptor-mediated apoptosis by 1,25-dihydroxyvitamin d3 revealed by microarray analysis
a binding site tyrosine shapes desensitization kinetics and agonist potency at glur
pc2-mediated sumoylation of smad-interacting protein 1 attenuates transcriptional repression of e-cadherin
the conformationally dynamic c helix of the ri subunit of protein kinase a mediates isoform-specific domain reorganization upon c subunit binding
clavulanic acid inactivation of shv-1 and the inhibitor-resistant s130g shv-1 -lactamase
mutational analysis of the catalytic domain of o-linked n-acetylglucosaminyl transferase
a specific microdomain (“glycosynapse 3“) controls phenotypic conversion and reversion of bladder cancer cells through gm3-mediated interaction of 31 integrin wit..
structure and lytic activity of a bacillus anthracis prophage endolysin
analysis of the functional modules of the trna 3‘ endonuclease (trnase z)
ultraviolet b radiation generates platelet-activating factor-like phospholipids underlying cutaneous damage
sox9 and p300 cooperatively regulate chromatin-mediated transcription
nuclear factor of activated t cells c1 induces osteoclast-associated receptor gene expression during tumor necrosis factor-related activation-induced cytokine-media..
apoptosis induced by the kinase inhibitor bay 43-9006 in human leukemia cells involves down-regulation of mcl-1 through inhibition of translation
the optimedin gene is a downstream target of pax6
identification of a repressor in the first intron of the human 2(i) collagen gene (col1a2)
human mitochondrial clpp is a stable heptamer that assembles into a tetradecamer in the presence of clpx
yxin is a modular protein combining a dexd/h core and a specific rna-binding domain
spontaneous thermal motion of the gabaa receptor m2 channel-lining segments
effects of rna interference of trypanosoma brucei structure-specific endonuclease-i on kinetoplast dna replication
early growth response gene 1 (egr1) regulates heparanase gene transcription in tumor cells
synthetic lethal interaction of the mitochondrial phosphatidylethanolamine and cardiolipin biosynthetic pathways in saccharomyces cerevisiae
selective metal binding to a membrane-embedded aspartate in the escherichia coli metal transporter yiip (fief)
the core histone n-terminal tail domains function independently and additively during salt-dependent oligomerization of nucleosomal arrays
the immune modulator fty720 inhibits sphingosine-1-phosphate lyase activity
prostaglandin i2 production and camp accumulation in response to acidic extracellular ph through ogr1 in human aortic smooth muscle cells
cys-trnapro editing by haemophilus influenzae ybak via a novel synthetase·ybak·trna ternary complex
identification of the surfactant protein a receptor 210 as the unconventional myosin 18a
plasmin- and thrombin-accelerated shedding of syndecan-4 ectodomain generates cleavage sites at lys114-arg115 and lys129-val130 bonds
biosynthesis of amphotericin derivatives lacking exocyclic carboxyl groups
the essential light chain n-terminal extension alters force and fiber kinetics in mouse cardiac muscle
protein complexes of the escherichia coli cell envelope
domains and maturation processes that regulate the activity of adamts-2, a metalloproteinase cleaving the aminopropeptide of fibrillar procollagens types i-iii and v
attenuation of insulin-stimulated insulin receptor substrate-1 serine 307 phosphorylation in insulin resistance of type 2 diabetes
elevation of rnase r in response to multiple stress conditions
engineering functional changes in escherichia coli endonuclease iii based on phylogenetic and structural analyses
launching of the yeast 20 s rna narnavirus by expressing the genomic or antigenomic viral rna in vivo
lass5 is a bona fide dihydroceramide synthase that selectively utilizes palmitoyl-coa as acyl donor
mediator and tfiih govern carboxyl-terminal domain-dependent transcription in yeast extracts
characterizing the non-reducing end structure of heparan sulfate
b-aggressive lymphoma family proteins have unique domains that modulate transcription and exhibit poly(adp-ribose) polymerase activity
glutamate cysteine ligase catalysis
tyrosine modification is not required for myeloperoxidase-induced loss of apolipoprotein a-i functional activities
copper stress causes an in vivo requirement for the escherichia coli disulfide isomerase dsbc
regulation of the dynamics of hsp90 action on the glucocorticoid receptor by acetylation/deacetylation of the chaperone
n-linked glycosylation is required for nicotinic receptor assembly but not for subunit associations with calnexin
chlortetracycline and demeclocycline inhibit calpains and protect mouse neurons against glutamate toxicity and cerebral ischemia
down-regulation of factor ixa in the factor xase complex by protein z-dependent protease inhibitor
identification of mammalian proteins cross-linked to dna by ionizing radiation
the dna-dependent protein kinase catalytic subunit phosphorylation sites in human artemis
calmodulin binds to the cytoplasmic domain of angiotensin-converting enzyme and regulates its phosphorylation and cleavage secretion
cross-talk among gp130 cytokines in adipocytes
oxidative stress is responsible for mitochondrial permeability transition induction by salicylate in liver mitochondria
glucocorticoids regulate transcription of the gene for phosphoenolpyruvate carboxykinase in the liver via an extended glucocorticoid regulatory unit
interaction of hemojuvelin with neogenin results in iron accumulation in human embryonic kidney 293 cells
caspartin and calprismin, two proteins of the shell calcitic prisms of the mediterranean fan mussel pinna nobilis
proteasomes mediate prolactin-induced receptor down-regulation and fragment generation in breast cancer cells
tumor necrosis factor (tnf) induces the unfolded protein response (upr) in a reactive oxygen species (ros)-dependent fashion, and the upr counteracts ros accumulati..
phorbol ester-induced g1 phase arrest selectively mediated by protein kinase c-dependent induction of p21
cyclic nucleotides, the photosynthetic apparatus and response to a uv-b stress in the cyanobacterium synechocystis sp. pcc 6803
ib kinase regulates subcellular distribution and turnover of cyclin d1 by phosphorylation
functional analysis of early secreted antigenic target-6, the dominant t-cell antigen of mycobacterium tuberculosis, reveals key residues involved in secretion, com..
basis for selectivity of cationic antimicrobial peptides for bacterial versus mammalian membranes
pseudoapoptosis induced by brief activation of atp-gated p2x7 receptors
crystal structure and functional analysis of lipoamide dehydrogenase from mycobacterium tuberculosis
toll-like receptor 3 and stat-1 contribute to double-stranded rna+ interferon--induced apoptosis in primary pancreatic -cells
potent mechanism-based inhibitors for matrix metalloproteinases
the identification of apoptosis-related residues in human thymosin -10 by mutational analysis and computational modeling
ephrina1 repulsive response is regulated by an epha2 tyrosine phosphatase
shedding of collagen xvii ectodomain depends on plasma membrane microenvironment
wild-type pink1 prevents basal and induced neuronal apoptosis, a protective effect abrogated by parkinson disease-related mutations
mso1 is a novel component of the yeast exocytic snare complex
smad-dependent cooperative regulation of interleukin 2 receptor chain gene expression by t cell receptor and transforming growth factor-
the role of ubiquitination in drosophila innate immunity
anthrax biosensor, protective antigen ion channel asymmetric blockade
nap1 modulates binding of linker histone h1 to chromatin and induces an extended chromatin fiber conformation
insights into the human cd59 complement binding interface toward engineering new therapeutics
crystal structures representing the michaelis complex and the thiouronium reaction intermediate of pseudomonas aeruginosa arginine deiminase
ubiquilin-1 regulates nicotine-induced up-regulation of neuronal nicotinic acetylcholine receptors
activation of the hetero-octameric atp phosphoribosyl transferase through subunit interface rearrangement by a trna synthetase paralog
selective vulnerability of dopaminergic neurons to microtubule depolymerization
human sco1 and sco2 function as copper-binding proteins
identification of mmp-15 as an anti-apoptotic factor in cancer cells
the epstein-barr virus protein, latent membrane protein 2a, co-opts tyrosine kinases used by the t cell receptor
unwinding of the nascent lagging strand by rep and pria enables the direct restart of stalled replication forks
evidence for the involvement of tyrosine kinase zap 70 in nuclear retinoid receptor-dependent transactivation in t lymphocytes
full-length p73 represses drug-induced apoptosis in small cell lung carcinoma cells
improved photobiological h2 production in engineered green algal cells
independent regulation of hsp70 and hsp90 chaperones by hsp70/hsp90-organizing protein sti1 (hop1)
-amyloid is different in normal aging and in alzheimer disease
deconvolution of a complex target using dna aptamers
mechanisms of statin-mediated inhibition of small g-protein function
mammary serine protease inhibitor (maspin) binds directly to interferon regulatory factor
wnk1 activates sgk1 by a phosphatidylinositol 3-kinase-dependent and non-catalytic mechanism
a novel mechanism of modulation of hyperpolarization-activated cyclic nucleotide-gated channels by src kinase
the opportunistic pathogen toxoplasma gondii deploys a diverse legion of invasion and survival proteins
proteomic analysis of rhoptry organelles reveals many novel constituents for host-parasite interactions in toxoplasma gondii
partial agonism in a g protein-coupled receptor
monokine induced by interferon- acts as a neurotrophic factor on pc12 cells and rat primary sympathetic neurons
structural analysis of siah1-siah-interacting protein interactions and insights into the assembly of an e3 ligase multiprotein complex
modulation of apolipoprotein e structure by domain interaction
identification of the cyclamate interaction site within the transmembrane domain of the human sweet taste receptor subunit t1r3
modification of the stat1 sh2 domain broadly improves interferon efficacy in proportion to p300/creb-binding protein coactivator recruitment
magnesium and phosphate ions enable nad binding to methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase
thermostable mutants of the photoprotein aequorin obtained by in vitro evolution
the lactococcus lactis cody regulon
functional consequences of hypertrophic and dilated cardiomyopathy-causing mutations in -tropomyosin
endoplasmic reticulum-directed pex3p routes to peroxisomes and restores peroxisome formation in a saccharomyces cerevisiae pex3 strain
light-induced proton release of phytochrome is coupled to the transient deprotonation of the tetrapyrrole chromophore
influence of nonameric au-rich tristetraprolin-binding sites on mrna deadenylation and turnover
involvement of the p97-ufd1-npl4 complex in the regulated endoplasmic reticulum-associated degradation of inositol 1,4,5-trisphosphate receptors
the switch in alternative splicing of cyclic amp-response element modulator protein crem2 (activator) to crem (repressor) in human myometrial cells is mediated by s..
identification of hepatocyte growth factor activator inhibitor-1b as a potential physiological inhibitor of prostasin
biosynthesis of lipid-linked oligosaccharides in saccharomyces cerevisiae
binding and functions of adp-ribosylation factor on mammalian and yeast peroxisomes
mechanisms underlying energy-independent transfer of lipoproteins from lola to lolb, which have similar unclosed -barrel structures
processing of m1 rna at the 3‘ end protects its primary transcript from degradation
chemerin activation by serine proteases of the coagulation, fibrinolytic, and inflammatory cascades
the respiratory substrate rhodoquinol induces q-cycle bypass reactions in the yeast cytochrome bc1 complex
death-associated protein kinase as a sensor of mitochondrial membrane potential
functional expression of the human hcn3 channel
cellular sterol ester synthesis in plants is performed by an enzyme (phospholipid:sterol acyltransferase) different from the yeast and mammalian acyl-coa:sterol acy..
activation of nuclear factor b by somatostatin type 2 receptor in pancreatic acinar ar42j cells involves g14 and multiple signaling components
interaction of rna-binding proteins hur and auf1 with the human atf3 mrna 3‘-untranslated region regulates its amino acid limitation-induced stabilization
redox and spectroscopic properties of the escherichia coli nitric oxide-detoxifying system involving flavorubredoxin and its nadh-oxidizing redox partner
a novel set domain methyltransferase modifies ribosomal protein rpl23ab in yeast
sterol regulatory element-binding proteins activate insulin gene promoter directly and indirectly through synergy with beta2/e47
the enigmatic acyl carrier protein phosphodiesterase of escherichia coli
targeted intestinal overexpression of the immediate early gene tis7 in transgenic mice increases triglyceride absorption and adiposity
controlling -amyloid oligomerization by the use of naphthalene sulfonates
a gq/11-coupled mutant histamine h1 receptor f435a activated solely by synthetic ligands (rassl)
als2/alsin regulates rac-pak signaling and neurite outgrowth
the saccharomyces cerevisiae smc2/4 condensin compacts dna into (+) chiral structures without net supercoiling
characterization of single channel currents from primary cilia of renal epithelial cells
ph-dependent interaction of cytochrome c with mitochondrial mimetic membranes
the predicted coiled-coil domain of myosin 10 forms a novel elongated domain that lengthens the head
molecular modeling and site-directed mutagenesis of plant chloroplast monogalactosyldiacylglycerol synthase reveal critical residues for activity
identification of pama as a pii-binding membrane protein important in nitrogen-related and sugar-catabolic gene expression in synechocystis sp. pcc 6803
differential promotion of glutamate transporter expression and function by glucocorticoids in astrocytes from various brain regions
a functional role for the switch 2 region of yeast rna polymerase ii in transcription start site utilization and abortive initiation
active hsf1 significantly suppresses polyglutamine aggregate formation in cellular and mouse models
arabidopsis atdgk7, the smallest member of plant diacylglycerol kinases (dgks), displays unique biochemical features and saturates at low substrate concentration
peroxynitrite is a potent inhibitor of nf-b activation triggered by inflammatory stimuli in cardiac and endothelial cell lines
the vitamin k-dependent carboxylase has been acquired by leptospira pathogens and shows altered activity that suggests a role other than protein carboxylation
angiomotin regulates endothelial cell-cell junctions and cell motility
identification of an agonist-induced conformational change occurring adjacent to the ligand-binding pocket of the m3 muscarinic acetylcholine receptor
domain 5 of high molecular weight kininogen is antibacterial
fibulin-1 acts as a cofactor for the matrix metalloprotease adamts-1
the kinetics of pdz domain-ligand interactions and implications for the binding mechanism
a conserved glutamate residue in transmembrane helix 10 influences substrate specificity of rabbit oct2 (slc22a2)
folate metabolism in plants
the role of canonical transient receptor potential 7 in b-cell receptor-activated channels
cleavage of claspin by caspase-7 during apoptosis inhibits the chk1 pathway
multivalent interactions of calcium/calmodulin-dependent protein kinase ii with the postsynaptic density proteins nr2b, densin-180, and -actinin-2
demonstration of the pleiotrophin-binding oligosaccharide sequences isolated from chondroitin sulfate/dermatan sulfate hybrid chains of embryonic pig brains
protein kinase c delta induces apoptosis of vascular smooth muscle cells through induction of the tumor suppressor p53 by both p38-dependent and p38-independent mec..
proliferating cell nuclear antigen recruits cyclin-dependent kinase inhibitor xic1 to dna and couples its proteolysis to dna polymerase switching
the c-terminal domain of the xenopus cyclin-dependent kinase inhibitor, p27xic1, is both necessary and sufficient for phosphorylation-independent proteolysis
uncoupling ligand-dependent and -independent mechanisms for mitogen-activated protein kinase activation by the murine ron receptor tyrosine kinase
phosphorylation of numb family proteins
disease-related modifications in tau affect the interaction between fyn and tau
active-site peptide “fingerprinting“ of glycosidases in complex mixtures by mass spectrometry
distinct 3‘-untranslated region elements regulate stage-specific mrna accumulation and translation in leishmania
the b cell inhibitory fc receptor triggers apoptosis by a novel c-abl family kinase-dependent pathway
covalently dimerized seca is functional in protein translocation
identification and characterization of a novel human histone h3 lysine 36-specific methyltransferase
induction of the human oxidized base-specific dna glycosylase neil1 by reactive oxygen species
a phosphorylation-dependent export structure in romk (kir 1.1) channel overrides an endoplasmic reticulum localization signal
crystal structure of smcl, a bacterial neutral sphingomyelinase c from listeria
h-ras dynamically interacts with recycling endosomes in cho-k1 cells
tumor-suppressive maspin regulates cell response to oxidative stress by direct interaction with glutathione s-transferase
rabphilin localizes with the cell actin cytoskeleton and stimulates association of granules with f-actin cross-linked by -actinin
hypertonic induction of cox-2 in collecting duct cells by reactive oxygen species of mitochondrial origin
structural and mechanistic studies on carboxymethylproline synthase (carb), a unique member of the crotonase superfamily catalyzing the first step in carbapenem bio..
modification of the structure and function of fibrillin-1 by homocysteine suggests a potential pathogenetic mechanism in homocystinuria
the amino-terminal domain of clpb supports binding to strongly aggregated proteins
pex3p initiates the formation of a preperoxisomal compartment from a subdomain of the endoplasmic reticulum in saccharomyces cerevisiae
a novel form of neurotensin post-translationally modified by arginylation
an intron-encoded protein assists rna splicing of multiple similar introns of different bacterial genes
regulation of the transcriptional activity of c-fos by erk
identification and characterization of a novel mammalian caspase with proapoptotic activity
sequence determinants of enhanced amyloidogenicity of alzheimer a42 peptide relative to a40
phospholipid scramblase 1 binds to the promoter region of the inositol 1,4,5-triphosphate receptor type 1 gene to enhance its expression
chemical genetic engineering of g protein-coupled receptor kinase 2
identification of residues responsible for ligand recognition and regioisomeric selectivity of lysophosphatidic acid receptors expressed in mammalian cells
characterization of a rabbit kidney prostaglandin f2 receptor exhibiting gi-restricted signaling that inhibits water absorption in the collecting duct
transcription of the nr1 subunit of the n-methyl-d-aspartate receptor is down-regulated by excitotoxic stimulation and cerebral ischemia
dlx5 specifically regulates runx2 type ii expression by binding to homeodomain-response elements in the runx2 distal promoter
yeast pex14p possesses two functionally distinct pex5p and one pex7p binding sites
cyclopentenone isoprostanes inhibit the inflammatory response in macrophages
arabidopsis brs1 is a secreted and active serine carboxypeptidase
histidylated lipid-modified sendai viral envelopes mediate enhanced membrane fusion and potentiate targeted gene delivery
a role for human sp as a pattern recognition receptor
molecular characterization of the gallate dioxygenase from pseudomonas putida kt244
characterization of the oxidase activity in mammalian catalase
jnk and tumor necrosis factor- mediate free fatty acid-induced insulin resistance in 3t3-l1 adipocytes
involvement of endogenous bone morphogenetic protein (bmp) 2 and bmp6 in bone formation
a switch 3 point mutation in the subunit of transducin yields a unique dominant-negative inhibitor
docking and rolling, a model of how the mitotic motor eg5 works
the contribution of apoptosis-inducing factor, caspase-activated dnase, and inhibitor of caspase-activated dnase to the nuclear phenotype and dna degradation during..
origin of informational polymers
retinoid absorption and storage is impaired in mice lacking lecithin:retinol acyltransferase (lrat)
rational design of p53, an intrinsically unstructured protein, for the fabrication of novel molecular sensors
extracellular application of nicotinic acid adenine dinucleotide phosphate induces ca2+ signaling in astrocytes in situ
the p62 scaffold regulates nerve growth factor-induced nf-b activation by influencing traf6 polyubiquitination
enhanced ubiquitylation and accelerated degradation of the dopamine transporter mediated by protein kinase c
apbp-1, a dna/rna-binding protein, interacts with the chick aggrecan regulatory region
identification of three gp350/220 regions involved in epstein-barr virus invasion of host cells
development of zinc finger domains for recognition of the 5‘-cnn-3‘ family dna sequences and their use in the construction of artificial transcription factors
identification and characterization of neub3 from campylobacter jejuni as a pseudaminic acid synthase
reactive oxygen species-mediated -cleavage of the prion protein in the cellular response to oxidative stress
characterizing sterol defect suppressors uncovers a novel transcriptional signaling pathway regulating zymosterol biosynthesis
unsaturated fatty acids phosphorylate and destabilize abca1 through a phospholipase d2 pathway
serum amyloid a promotes cholesterol efflux mediated by scavenger receptor b-i
cloning, functional expression, and characterization of cyp709c1, the first sub-terminal hydroxylase of long chain fatty acid in plants
two hla-b14 subtypes (b1402 and b1403) differentially associated with ankylosing spondylitis differ substantially in peptide specificity but have limited peptide an..
the frameshift mutation in nod2 results in unresponsiveness not only to nod2- but also nod1-activating peptidoglycan agonists
regulation of microfilament organization by kaposi sarcoma-associated herpes virus-cyclin·cdk6 phosphorylation of caldesmon
a picrotoxin-specific conformational change in the glycine receptor m2-m3 loop
mtor-dependent suppression of protein phosphatase 2a is critical for phospholipase d survival signals in human breast cancer cells
lethal cutaneous disease in transgenic mice conditionally expressing type i human t cell leukemia virus tax
multiple conformations in the ligand-binding site of the yeast nuclear pore-targeting domain of nup116p
histidine-rich glycoprotein specifically binds to necrotic cells via its amino-terminal domain and facilitates necrotic cell phagocytosis
release of opa1 during apoptosis participates in the rapid and complete release of cytochrome c and subsequent mitochondrial fragmentation
normal and cystic fibrosis airway surface liquid homeostasis
the chemokine sdf-1/cxcl12 binds to and signals through the orphan receptor rdc1 in t lymphocytes
pivotal role of akt activation in mitochondrial protection and cell survival by poly(adp-ribose)polymerase-1 inhibition in oxidative stress
serinc, an activity-regulated protein family, incorporates serine into membrane lipid synthesis
direct modulation of kir channel gating by membrane phosphatidylinositol 4,5-bisphosphate
hydrogen peroxide is generated during the very early stages of aggregation of the amyloid peptides implicated in alzheimer disease and familial british dementia
mekk4 is an effector of the embryonic traf4 for jnk activation
the synthetic cannabinoid r(+)win 55,212-2 inhibits the interleukin-1 signaling pathway in human astrocytes in a cannabinoid receptor-independent manner
rapid effects of dexamethasone on intracellular ph and na+/h+ exchanger activity in human bronchial epithelial cells
fully metallated s134n cu,zn-superoxide dismutase displays abnormal mobility and intermolecular contacts in solution
yeast pias-type ull1/siz1 is composed of sumo ligase and regulatory domains
essential mechanisms in the catalysis of peptide bond formation on the ribosome
app1 transcription is regulated by inositol-phosphorylceramide synthase 1-diacylglycerol pathway and is controlled by atf2 transcription factor in cryptococcus neof..
functions of the per/arnt/sim domains of the hypoxia-inducible factor
7 integrin expression is negatively regulated by ef1 during skeletal myogenesis
distinct protein phosphatase 2a heterotrimers modulate growth factor signaling to extracellular signal-regulated kinases and akt
s100a1 enhances the l-type ca2+ current in embryonic mouse and neonatal rat ventricular cardiomyocytes
dual specificity mapk phosphatase 3 activates pepck gene transcription and increases gluconeogenesis in rat hepatoma cells
cadherins mediate both the association between ps1 and -catenin and the effects of ps1 on -catenin stability
endothelial thrombomodulin induces ca2+ signals and nitric oxide synthesis through epidermal growth factor receptor kinase and calmodulin kinase ii
epidermal growth factor-induced rapid retinoblastoma phosphorylation at ser780 and ser795 is mediated by erk1/2 in small intestine epithelial cells
deletion of the glucosidase ii gene in trypanosoma brucei reveals novel n-glycosylation mechanisms in the biosynthesis of variant surface glycoprotein
src kinase activates endothelial nitric-oxide synthase by phosphorylating tyr-83
uncoupling crk signal transduction by pseudomonas exoenzyme t
msba is not required for phospholipid transport in neisseria meningitidis
calcium/calmodulin regulates ubiquitination of the ubiquitin-specific protease tre17/usp6
positive regulation of ib kinase signaling by protein serine/threonine phosphatase 2a
estrogen regulation of adiposity and fuel partitioning
essential constituents of the 3‘-phosphoesterase domain of bacterial dna ligase d, a nonhomologous end-joining enzyme
control of aspp2/53bp2l protein levels by proteasomal degradation modulates p53 apoptotic function
toward an assembly line for u7 snrnps
self-association of iqgap
post-translational regulation of mercaptopyruvate sulfurtransferase via a low redox potential cysteine-sulfenate in the maintenance of redox homeostasis
elucidating the role of h/aca-like rnas in trans-splicing and rrna processing via rna interference silencing of the trypanosoma brucei cbf5 pseudouridine synthase
reassessment of protein stability, dna binding, and protection of mycobacterium smegmatis dps
free fatty acids repress the glut4 gene expression in cardiac muscle via novel response elements
phosphorylation of rela/p65 on serine 536 defines an ib-independent nf-b pathway
phosphorylation of y14 modulates its interaction with proteins involved in mrna metabolism and influences its methylation
the c-terminal appended domain of human cytosolic leucyl-trna synthetase is indispensable in its interaction with arginyl-trna synthetase in the multi-trna syntheta..
high resolution crystal structures of the trans-enamine intermediates formed by sulbactam and clavulanic acid and e166a shv-1 -lactamase
inhibition of metabotropic glutamate receptor signaling by the huntingtin-binding protein optineurin
a nine-transmembrane domain topology for presenilin 1
tumor necrosis factor (tnf) increases collagen accumulation and proliferation in intestinal myofibroblasts via tnf receptor 2
glycerophosphocholine-dependent growth requires gde1p (ypl110c) and git1p in saccharomyces cerevisiae
sirp1 is expressed as a disulfide-linked homodimer in leukocytes and positively regulates neutrophil transepithelial migration
activation of membrane cholesterol by displacement from phospholipids
fancc, fance, and fancd2 form a ternary complex essential to the integrity of the fanconi anemia dna damage response pathway
menkes copper atpase (atp7a) is a novel metal-responsive gene in rat duodenum, and immunoreactive protein is present on brush-border and basolateral membrane domains
the structure of bypass of forespore c, an intercompartmental signaling factor during sporulation in bacillus
localization of a substrate binding domain of the human reduced folate carrier to transmembrane domain 11 by radioaffinity labeling and cysteine-substituted accessi..
the intracellular trafficking of the g protein-coupled receptor tp depends on a direct interaction with rab11
epidermal growth factor receptor acts as a negative regulator for bacterium nontypeable haemophilus influenzae-induced toll-like receptor 2 expression via an src-de..
stable dna opening within open promoter complexes is mediated by the rna polymerase ‘-jaw domain
structural and mutational analyses of the molecular interactions between the catalytic domain of factor xia and the kunitz protease inhibitor domain of protease nex..
the - and -subunits of the human udp-n-acetylglucosamine:lysosomal enzyme phosphotransferase are encoded by a single cdna
identification and functional characterization of a voltage-gated chloride channel and its novel splice variant in taste bud cells
dpp-responsive silencers are bound by a trimeric mad-medea complex
hsp90 recruited by sp1 is important for transcription of 12(s)-lipoxygenase in a431 cells
2-cyano-3,12-dioxooleana-1,9-dien-28-imidazolide (cddo-im) directly targets mitochondrial glutathione to induce apoptosis in pancreatic cancer
c-terminal recognition by 14-3-3 proteins for surface expression of membrane receptors
alg14 recruits alg13 to the cytoplasmic face of the endoplasmic reticulum to form a novel bipartite udp-n-acetylglucosamine transferase required for the second step..
pdx-1 links histone h3-lys-4 methylation to rna polymerase ii elongation during activation of insulin transcription
identification and characterization of a second chromophore of dna photolyase from thermus thermophilus hb27
physiological and receptor-selective retinoids modulate interferon signaling by increasing the expression, nuclear localization, and functional activity of interfer..
hepatitis c virus nonstructural protein 5a (ns5a) is an rna-binding protein
determinants of substrate specificity in -aminotransferases
assembly of an rna-protein complex
acrolein impairs atp binding cassette transporter a1-dependent cholesterol export from cells through site-specific modification of apolipoprotein a-i
role of mrna stability during genome-wide adaptation of lactococcus lactis to carbon starvation
a single pair of acidic residues in the kinase major groove mediates strong substrate preference for p-2 or p-5 arginine in the agc, camk, and ste kinase families
nuclear targeting of protein phosphatase-1 by hiv-1 tat protein
modulation of androgen receptor transactivation by foxh
cd46 plays a key role in tailoring innate immune recognition of apoptotic and necrotic cells
the psce-pscf-pscg complex controls type iii secretion needle biogenesis in pseudomonas aeruginosa
cell cycle defects contribute to a block in hormone-induced mammary gland proliferation in ccaat/enhancer-binding protein (c/ebp)-null mice
-secretase is a functional component of phagosomes
involvement of n-terminal-extended form of sphingosine kinase 2 in serum-dependent regulation of cell proliferation and apoptosis
the homophilic binding of junctional adhesion molecule-c mediates tumor cell-endothelial cell interactions
subcellular compartmentation and differential catalytic properties of the three human nicotinamide mononucleotide adenylyltransferase isoforms
a mammalian actin substitution in yeast actin (h372r) causes a suppressible mitochondria/vacuole phenotype
sparc regulates extracellular matrix organization through its modulation of integrin-linked kinase activity
platelet-derived growth factor and reactive oxygen species (ros) regulate ras protein levels in primary human fibroblasts via erk1/
characterization of hcinap, a novel coilin-interacting protein encoded by a transcript from the transcription factor tafiid32 locus
expression signature of the mouse prostate
the origin of c1a-c2 interdomain interactions in protein kinase c
huntingtin associates with acidic phospholipids at the plasma membrane
rna interference-directed knockdown of urokinase plasminogen activator and urokinase plasminogen activator receptor inhibits prostate cancer cell invasion, survival..
inhibition of cyclin-dependent kinase 1 induces cytokinesis without chromosome segregation in an ect2 and mgcracgap-dependent manner
tumor necrosis factor- triggers mucus production in airway epithelium through an ib kinase -dependent mechanism
human tdp1 cleaves a broad spectrum of substrates, including phosphoamide linkages
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