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activation of mitogen-activated protein kinase kinase (mkk) 3 and mkk6 by type i interferons
the phosphate carrier has an ability to be sorted to either the tim22 pathway or the tim23 pathway for its import into yeast mitochondria
an atypical tumor necrosis factor (tnf) receptor-associated factor-binding motif of b cell-activating factor belonging to the tnf family (baff) receptor mediates in..
simultaneous inhibition of epidermal growth factor receptor (egfr) signaling and enhanced activation of tumor necrosis factor-related apoptosis-inducing ligand (tra..
induction of leptin receptor expression in the liver by leptin and food deprivation
resistance to endotoxic shock in endothelial nitric-oxide synthase (enos) knock-out mice
trichostatin a induces transforming growth factor type ii receptor promoter activity and acetylation of sp1 by recruitment of pcaf/p300 to a sp1·nf-y complex
smad and p38 mapk signaling pathways independently regulate 1(i) collagen gene expression in unstimulated and transforming growth factor--stimulated hepatic stellat..
transcriptional responses of escherichia coli to s-nitrosoglutathione under defined chemostat conditions reveal major changes in methionine biosynthesis
nitric oxide inhibits mammalian methylmalonyl-coa mutase
fbw2 targets gcma to the ubiquitin-proteasome degradation system
modulation of the mammalian target of rapamycin pathway by diacylglycerol kinase-produced phosphatidic acid
transcriptional activity of the paired-like homeodomain proteins chx10 and vsx1
peroxisome proliferator-activated receptor -independent activation of p38 mapk by thiazolidinediones involves calcium/calmodulin-dependent protein kinase ii and pro..
meis c termini harbor transcriptional activation domains that respond to cell signaling
big1 is a binding partner of myosin ixb and regulates its rho-gtpase activating protein activity
activation of the iron regulon by the yeast aft1/aft2 transcription factors depends on mitochondrial but not cytosolic iron-sulfur protein biogenesis
p125 is localized in endoplasmic reticulum exit sites and involved in their organization
cd80 binding polyproline helical peptide inhibits t cell activation
transmembrane topology of the protein palmitoyl transferase akr1
daxx mediates the small ubiquitin-like modifier-dependent transcriptional repression of smad4
regulatory interactions between the amino terminus of g-protein subunits and the catalytic domain of phospholipase c2
thrombin-induced rapid geranylgeranylation of rhoa as an essential process for rhoa activation in endothelial cells
resurrecting the ancestral enzymatic role of a modulatory subunit
xenopus laevis cyp17 regulates androgen biosynthesis independent of the cofactor cytochrome b5
cystic fibrosis airway epithelial ca2+i signaling
interaction between the catalytic site and the a-m3 linker stabilizes e2/e2p conformational states of na+,k+-atpase
identification and functional characterization of a 5-transmembrane domain variant isoform of the nts2 neurotensin receptor in rat central nervous system
design and construction of highly stable, protease-resistant chimeric avidins
dual functionality of the anti-1 integrin antibody, 12g10, exemplifies agonistic signalling from the ligand binding pocket of integrin adhesion receptors
src phosphorylates ezrin at tyrosine 477 and induces a phosphospecific association between ezrin and a kelch-repeat protein family member
platelet-derived growth factor stimulates src-dependent mrna stabilization of specific early genes in fibroblasts
sirt1 deacetylation and repression of p300 involves lysine residues 1020/1024 within the cell cycle regulatory domain 1
ap-1 and ap-3 facilitate lysosomal targeting of batten disease protein cln3 via its dileucine motif
effect of myriocin on plasma sphingolipid metabolism and atherosclerosis in apoe-deficient mice
lipid infusion decreases the expression of nuclear encoded mitochondrial genes and increases the expression of extracellular matrix genes in human skeletal muscle
differential oxidation of protein-tyrosine phosphatases
molecular cloning of mouse type 2 and type 3 inositol 1,4,5-trisphosphate receptors and identification of a novel type 2 receptor splice variant
mitotic phosphorylation rescues abl from f-actin-mediated inhibition
a novel nf-b pathway involving ikk and p65/rela ser-536 phosphorylation results in p53 inhibition in the absence of nf-b transcriptional activity
flux of fatty acids through npc1 lysosomes
complete reversal of coenzyme specificity of xylitol dehydrogenase and increase of thermostability by the introduction of structural zinc
basement membrane distortions impair lung lobation and capillary organization in the mouse model for fraser syndrome
prostaglandin f2-mediated activation of apoptotic signaling cascades in the corpus luteum during apoptosis
roles of conserved amino acid sequence motifs in the spou (trmh) rna methyltransferase family
a molecular mechanism for lipopolysaccharide protection of gram-negative bacteria from antimicrobial peptides
yersinia phosphatase induces mitochondrially dependent apoptosis of t cells
cytochrome b6 arginine 214 of synechococcus sp. pcc 7002, a key residue for quinone-reductase site function and turnover of the cytochrome bf complex
altering substrate chain length specificity of an acylhomoserine lactone synthase in bacterial communication
characterization of two protein disulfide isomerases from the endocytic pathway of bloodstream forms of trypanosoma brucei
differential regulation of phosphoglucose isomerase/autocrine motility factor activities by protein kinase ck2 phosphorylation
cloning, sequencing, and characterization of alternatively spliced glutaredoxin 1 cdna and its genomic gene
a dictyostelium mutant with reduced lysozyme levels compensates by increased phagocytic activity
neuritic beading induced by activated microglia is an early feature of neuronal dysfunction toward neuronal death by inhibition of mitochondrial respiration and axo..
n-cadherin mediates endocytosis of candida albicans by endothelial cells
cellular stability of serotonin n-acetyltransferase conferred by phosphonodifluoromethylene alanine (pfa) substitution for ser-205
hrs, a mammalian master molecule in vesicular transport and protein sorting, suppresses the degradation of escrt proteins signal transducing adaptor molecule 1 and 2
syntaxin 6 and vti1b form a novel snare complex, which is up-regulated in activated macrophages to facilitate exocytosis of tumor necrosis factor-
loss of rb-e2f repression results in caspase-8-mediated apoptosis through inactivation of focal adhesion kinase
specific cleavage of mcl-1 by caspase-3 in tumor necrosis factor-related apoptosis-inducing ligand (trail)-induced apoptosis in jurkat leukemia t cells
distinct golgi populations of phosphatidylinositol 4-phosphate regulated by phosphatidylinositol 4-kinases
cisplatin inactivation of caspases inhibits death ligand-induced cell death in vitro and fulminant liver damage in mice
glycosylation-related gene expression in prion diseases
crystal structures and amidolytic activities of two glycosylated snake venom serine proteinases
role of leucine 31 of phospholamban in structural and functional interactions with the ca2+ pump of cardiac sarcoplasmic reticulum
engineering of a recombinant vitamin k-dependent -carboxylation system with enhanced -carboxyglutamic acid forming capacity
the role of lip5 and chmp5 in multivesicular body formation and hiv-1 budding in mammalian cells
licorice compounds glycyrrhizin and 18-glycyrrhetinic acid are potent modulators of bile acid-induced cytotoxicity in rat hepatocytes
signaling mechanisms responsible for lysophosphatidic acid-induced urokinase plasminogen activator expression in ovarian cancer cells
gene trap mutagenesis-based forward genetic approach reveals that the tumor suppressor ovca1 is a component of the biosynthetic pathway of diphthamide on elongation..
role of the hepatocyte nuclear factor-1 (hnf-1) c-terminal domain in pkhd1 (arpkd) gene transcription and renal cystogenesis
distinct domains control the addressing and the insertion of bax into mitochondria
phospholipid scramblase 1 contains a nonclassical nuclear localization signal with unique binding site in importin
investigating the effects of mutations on protein aggregation in the cell
the antineoplastic lectin of the common edible mushroom (agaricus bisporus) has two binding sites, each specific for a different configuration at a single epimeric ..
integrin engagement differentially modulates epithelial cell motility by rhoa/rock and pak1
functional insights from the structure of the multifunctional c345c domain of c5 of complement
calcium-dependent open/closed conformations and interfacial energy maps of reconstituted hemichannels
a novel protein derived from the muc1 gene by alternative splicing and frameshifting
molecular mechanism underlying partial and full agonism mediated by the human cholecystokinin-1 receptor
carrier-independent nuclear import of the transcription factor pu.1 via rangtp-stimulated binding to nup153
bzdr, a repressor that controls the anaerobic catabolism of benzoate in azoarcus sp. cib, is the first member of a new subfamily of transcriptional regulators
reaction of morphinone reductase with 2-cyclohexen-1-one and 1-nitrocyclohexene
a novel mechanism for jak2 activation by a g protein-coupled receptor, the cck2r
csx/nkx2.5 modulates differentiation of skeletal myoblasts and promotes differentiation into neuronal cells in vitro
rs1, a discoidin domain-containing retinal cell adhesion protein associated with x-linked retinoschisis, exists as a novel disulfide-linked octamer
structural and kinetic analyses of arginine residues in the active site of the acetate kinase from methanosarcina thermophila
exceptional disfavor for proline at the p+1 position among agc and camk kinases establishes reciprocal specificity between them and the proline-directed kinases
socs-3 induces myoblast differentiation
atomic force microscopy imaging demonstrates that p2x2 receptors are trimers but that p2x6 receptor subunits do not oligomerize
peroxisome proliferator-activated receptor-binding protein null mutation results in defective mammary gland development
kinetic and structural analysis of -d-glucose-1-phosphate cytidylyltransferase from salmonella typhi
nicotine inactivation of the proapoptotic function of bax through phosphorylation
superoxide anions are involved in mediating the effect of low k intake on c-src expression and renal k secretion in the cortical collecting duct
multiple full-length ns3 molecules are required for optimal unwinding of oligonucleotide dna in vitro
the e6ap ubiquitin ligase is required for transactivation of the htert promoter by the human papillomavirus e6 oncoprotein
long-chain acyl-coa synthetase 6 preferentially promotes dha metabolism
ku is a novel transcriptional recycling coactivator of the androgen receptor in prostate cancer cells
purified bacillus anthracis lethal toxin complex formed in vitro and during infection exhibits functional and biological activity
amplification of telomeric arrays via rolling-circle mechanism
regulation of mitochondrial nadp+-dependent isocitrate dehydrogenase activity by glutathionylation
atp-dependent and atp-independent roles for the rad54 chromatin remodeling enzyme during recombinational repair of a dna double strand break
mechanisms responsible for the promoter-specific effects of myocardin
type i transforming growth factor receptor binds to and activates phosphatidylinositol 3-kinase
a methanocaldococcus jannaschii archaeal signature gene encodes for a 5-formaminoimidazole-4-carboxamide-1--d-ribofuranosyl 5‘-monophosphate synthetase
reduction in the e2k subunit of the -ketoglutarate dehydrogenase complex has effects independent of complex activity
characterization of oligosaccharide ligands expressed on sw1116 cells recognized by mannan-binding protein
regulation of amphetamine-stimulated dopamine efflux by protein kinase c
the retroviral hypermutation specificity of apobec3f and apobec3g is governed by the c-terminal dna cytosine deaminase domain
oligopeptidase b from trypanosoma evansi
acidic extracellular ph induces matrix metalloproteinase-9 expression in mouse metastatic melanoma cells through the phospholipase d-mitogen-activated protein kinas..
hepatoma-derived growth factor
identification of a distal stat5-binding dna region that may mediate growth hormone regulation of insulin-like growth factor-i gene expression
cyclin d1 and c-myc internal ribosome entry site (ires)-dependent translation is regulated by akt activity and enhanced by rapamycin through a p38 mapk- and erk-dep..
furin directly cleaves prommp-2 in the trans-golgi network resulting in a nonfunctioning proteinase
function of phosphatidylinositol in mycobacteria
b23 regulates gadd45a nuclear translocation and contributes to gadd45a-induced cell cycle g2-m arrest
a functional link between store-operated and trpc channels revealed by the 3,5-bis(trifluoromethyl)pyrazole derivative, btp2
mechanistic studies of rhodobacter sphaeroides me2so reductase
glucosamine-induced activation of glycogen biosynthesis in isolated adipocytes
identification and mutational analysis of amino acid residues involved in dipyridamole interactions with human and caenorhabditis elegans equilibrative nucleoside t..
counteracting osmolyte trimethylamine n-oxide destabilizes proteins at ph below its pka
characterization of the oligomer structure of recombinant human mannan-binding lectin
structure/function analysis of 2a-adrenergic receptor interaction with g protein-coupledreceptor kinase 2
the small heat shock protein b-crystallin is a novel inhibitor of trail-induced apoptosis that suppresses the activation of caspase-3
differential single-stranded dna binding properties of the paralogous ssba and ssbb proteins from streptococcus pneumoniae
a five-coordinate metal center in co(ii)-substituted vanx
molecular characterization of n-acylethanolamine-hydrolyzing acid amidase, a novel member of the choloylglycine hydrolase family with structural and functional simi..
characterization of the protein dimerization domain responsible for assembly of functional selenodeiodinases
characterization of a conserved c-terminal motif (rsprr) in ribosomal protein s6 kinase 1 required for its mammalian target of rapamycin-dependent regulation
oxidative stress-mediated, post-translational loss of mafa protein as a contributing mechanism to loss of insulin gene expression in glucotoxic beta cells
brain contains a functional glucose-6-phosphatase complex capable of endogenous glucose production
stabilization of the unliganded glucocorticoid receptor by tsg101
differential phospholipid binding by site 3 and site 4 toxins
the guanine nucleotide exchange factor p63rhogef, a specific link between gq/11-coupled receptor signaling and rhoa
high affinity interaction with filamin a protects against calcium-sensing receptor degradation
c-abl tyrosine kinase regulates caspase-9 autocleavage in the apoptotic response to dna damage
heterodimerization of µ- and -opioid receptors occurs at the cell surface only and requires receptor-g protein interactions
the n-terminal peptide of the kaposi‘s sarcoma-associated herpesvirus (kshv)-cyclin determines substrate specificity
plasmon-waveguide resonance studies of lateral segregation of lipids and proteins into microdomains (rafts) in solid-supported bilayers
mapks (erk, p38) and akt can be phosphorylated by shear stress independently of platelet endothelial cell adhesion molecule-1 (cd31) in vascular endothelial cells
chromatin modification and the endothelial-specific activation of the e-selectin gene
functional consequences of the organization of the photosynthetic apparatus in rhodobacter sphaeroides
a mathematical model for the branched chain amino acid biosynthetic pathways of escherichia coli k12
a new tyrosyl radical on phe208 as ligand to the diiron center in escherichia coli ribonucleotide reductase, mutant r2-y122h
screening of 145 anti-prp monoclonal antibodies for their capacity to inhibit prpsc replication in infected cells
different from the hiv fusion inhibitor c34, the anti-hiv drug fuzeon (t-20) inhibits hiv-1 entry by targeting multiple sites in gp41 and gp120
mouse testican-
parathyroid hormone receptor trafficking contributes to the activation of extracellular signal-regulated kinases but is not required for regulation of camp signaling
o-fucosylation of notch occurs in the endoplasmic reticulum
the functional basis of mycophenolic acid resistance in candida albicans imp dehydrogenase
contributions of disulfide bonds in a nested pattern to the structure, stability, and biological functions of endostatin
crystal structure and binding properties of the serratia marcescens chitin-binding protein cbp21
cytosolic prion protein (prp) is not toxic in n2a cells and primary neurons expressing pathogenic prp mutations
binding of hepatitis c virus envelope protein e2 to cd81 up-regulates matrix metalloproteinase-2 in human hepatic stellate cells
solution nmr structure investigation for releasing mechanism of neocarzinostatin chromophore from the holoprotein
crystal structure of cd14 and its implications for lipopolysaccharide signaling
characterization and purification of saccharomyces cerevisiae rnase mrp reveals a new unique protein component
doublecortin association with actin filaments is regulated by neurabin ii
folding regulates autoprocessing of hiv-1 protease precursor
phosphoinositide 3-kinase is required for intracellular listeria monocytogenes actin-based motility and filopod formation
the nonconsecutive disulfide bond of escherichia coli phytase (appa) renders it dependent on the protein-disulfide isomerase, dsbc
prostaglandin e2 enhances osteoclastic differentiation of precursor cells through protein kinase a-dependent phosphorylation of tak1
microfibrils at basement membrane zones interact with perlecan via fibrillin-1
cannabinoid receptor-induced neurite outgrowth is mediated by rap1 activation through go/i-triggered proteasomal degradation of rap1gapii
engineering a selectable marker for hyperthermophiles
delta-interacting protein a, a new inhibitory partner of ccaat/enhancer-binding protein, implicated in adipocyte differentiation
the basolateral nhe1 na+/h+ exchanger regulates transepithelial absorption through actin cytoskeleton remodeling in renal thick ascending limb
lim-kinase 2 and cofilin phosphorylation mediate actin cytoskeleton reorganization induced by transforming growth factor-
oculodentodigital dysplasia-causing connexin43 mutants are non-functional and exhibit dominant effects on wild-type connexin43
the fission yeast protein ker1p is an ortholog of rna polymerase i subunit a14 in saccharomyces cerevisiae and is required for stable association of rrn3p and rpa21..
probing the mechanism of the archaeoglobus fulgidus inositol-1-phosphate synthase
a structural disulfide of yeast protein-disulfide isomerase destabilizes the active site disulfide of the n-terminal thioredoxin domain
asn792 participates in the hydrogen bond network around the k+-binding pocket of gastric h,k-atpase
crystal and solution structures of the helicase-binding domain of escherichia coli primase
nmr structure of the first phd finger of autoimmune regulator protein (aire1)
nitric oxide-dependent allosteric inhibitory role of a second nucleotide binding site in soluble guanylyl cyclase
crystal structure of foot-and-mouth disease virus 3c protease
activation of stat3 sequence-specific dna binding and transcription by p300/creb-binding protein-mediated acetylation
dissection of the mitochondrial import and assembly pathway for human tom40
homeobox-clock protein interaction in zebrafish
r1, a novel repressor of the human monoamine oxidase a
distinct conformations of the corticotropin releasing factor type 1 receptor adopted following agonist and antagonist binding are differentially regulated
mitotic kinesin inhibitors induce mitotic arrest and cell death in taxol-resistant and -sensitive cancer cells
interdimer processing and linearity of procaspase-3 activation
androgen receptor activation by gs signaling in prostate cancer cells
protein phosphatase 2a activity associated with golgi membranes during the g2/m phase may regulate phosphorylation of erk2
binding of two flaviolin substrate molecules, oxidative coupling, and crystal structure of streptomyces coelicolor a3(2) cytochrome p450 158a2
a novel isoform of the secretory pathway ca2+,mn2+-atpase, hspca2, has unusual properties and is expressed in the brain
trolox and 17-estradiol protect against amyloid -peptide neurotoxicity by a mechanism that involves modulation of the wnt signaling pathway
rhoa/rock signaling regulates sox9 expression and actin organization during chondrogenesis
co-chaperone chip associates with expanded polyglutamine protein and promotes their degradation by proteasomes
cytoskeleton-mediated death receptor and ligand concentration in lipid rafts forms apoptosis-promoting clusters in cancer chemotherapy
oxidative modifications and aggregation of cu,zn-superoxide dismutase associated with alzheimer and parkinson diseases
caveolae targeting and regulation of large conductance ca2+-activated k+ channels in vascular endothelial cells
junctional adhesion molecule 1 regulates epithelial cell morphology through effects on 1 integrins and rap1 activity
rap1 gtpase inhibits leukocyte transmigration by promoting endothelial barrier function
candidate metabolic network states in human mitochondria
gga proteins mediate the recycling pathway of memapsin 2 (bace)
decrypting the biochemical function of an essential gene from streptococcus pneumoniae using thermofluor® technology
a calmodulin binding domain of ryr increases activation of spontaneous ca2+ sparks in frog skeletal muscle
amplification of ca2+ signaling by diacylglycerol-mediated inositol 1,4,5-trisphosphate production
altered cholesterol metabolism in niemann-pick type c1 mouse brains affects mitochondrial function
wnt-dependent regulation of the e-cadherin repressor snail
selective activation of the mek-erk pathway is regulated by mechanical stimuli in forming joints and promotes pericellular matrix formation
interleukin-3 and granulocyte-macrophage colony-stimulating factor inhibits tumor necrosis factor (tnf)--induced osteoclast differentiation by down-regulation of ex..
solution structure of enzyme iiachitobiose from the n,n‘-diacetylchitobiose branch of the escherichia coli phosphotransferase system
intracellular positioning of isoforms explains an unusually large adenylate kinase gene family in the parasite trypanosoma brucei
erbin regulates mitogen-activated protein (map) kinase activation and map kinase-dependent interactions between merlin and adherens junction protein complexes in sc..
maize phosphoenolpyruvate carboxylase
identification of specific ligands for orphan olfactory receptors
serum response factor, an enriched cardiac mesoderm obligatory factor, is a downstream gene target for tbx genes
glutathione synthesis in streptococcus agalactiae
overexpression of proteasome 5 assembled subunit increases the amount of proteasome and confers ameliorated response to oxidative stress and higher survival rates
brn-3a transcription factor blocks p53-mediated activation of proapoptotic target genes noxa and bax in vitro and in vivo to determine cell fate
involvement of c-src and protein kinase c in the inhibition of cl-/oh- exchange activity in caco-2 cells by serotonin
ck2 phosphorylates ssrp1 and inhibits its dna-binding activity
modulation of endosomal cholesteryl ester metabolism by membrane cholesterol
the islet cell-enriched mafa activator is a key regulator of insulin gene transcription
the drosophila ninag oxidoreductase acts in visual pigment chromophore production
proline metabolism in procyclic trypanosoma brucei is down-regulated in the presence of glucose
identification of a novel class of target genes and a novel type of binding sequence of heat shock transcription factor in saccharomyces cerevisiae
stability of the topoisomerase ii closed clamp conformation may influence dna-stimulated atp hydrolysis
engineering glutathione transferase to a novel glutathione peroxidase mimic with high catalytic efficiency
the tsg-6 and ii interaction promotes a transesterification cleaving the protein-glycosaminoglycan-protein (pgp) cross-link
interaction of chromatin-associated plk1 and mcm7
enzymatic properties of purified murine fatty acid transport protein 4 and analysis of acyl-coa synthetase activities in tissues from fatp4 null mice
human cytomegalovirus ul84 is a phosphoprotein that exhibits utpase activity and is a putative member of the dexd/h box family of proteins
hyaluronan-cd44 interaction with iqgap1 promotes cdc42 and erk signaling, leading to actin binding, elk-1/estrogen receptor transcriptional activation, and ovarian ..
folding competence of n-terminally truncated forms of human procathepsin b
ecdysone-mediated up-regulation of the effector caspase drice is required for hormone-dependent apoptosis in drosophila cells
characterization of the yeast trimeric-sas acetyltransferase complex
activation of the trk signaling pathway by extracellular zinc
identification of lat4, a novel amino acid transporter with system l activity
seeding-dependent maturation of 2-microglobulin amyloid fibrils at neutral ph
direct role of chrebp·mlx in regulating hepatic glucose-responsive genes
lysophospholipid flipping across the escherichia coli inner membrane catalyzed by a transporter (lplt) belonging to the major facilitator superfamily
co-translational involvement of the chaperonin groel in the folding of newly translated polypeptides
regulation of chk2 by dna-dependent protein kinase
structural and functional features in human pde5a1 regulatory domain that provide for allosteric cgmp binding, dimerization, and regulation
cd4 down-regulation by hiv-1 and simian immunodeficiency virus (siv) nef proteins involves both internalization and intracellular retention mechanisms
regulation of complement c3 expression by the bile acid receptor fxr
evidence calcium pump binds magnesium before inorganic phosphate
positive and negative regulation of nuclear factor-b-mediated transcription by ib-, an inducible nuclear protein
t to c substitution at -175 or -173 of the -globin promoter affects gata-1 and oct-1 binding in vitro differently but can independently reproduce the hereditary per..
resveratrol and estradiol rapidly activate mapk signaling through estrogen receptors and in endothelial cells
a novel phosphatidylcholine-hydrolyzing phospholipase c induced by phosphate starvation in arabidopsis
roles of an ib kinase-related pathway in human cytomegalovirus-infected vascular smooth muscle cells
exploring the role of a unique carboxyl residue in emre by mass spectrometry
alternative mrna splicing of smrt creates functional diversity by generating corepressor isoforms with different affinities for different nuclear receptors
role of the streptokinase -domain in the interactions of streptokinase with plasminogen and plasmin
s-nitrosylation-dependent inactivation of akt/protein kinase b in insulin resistance
cytosolic phospholipase a2- is necessary for platelet-activating factor biosynthesis, efficient neutrophil-mediated bacterial killing, and the innate immune respons..
a functional analysis of mouse models of cardiac disease through metabolic profiling
endogenous methylarginines modulate superoxide as well as nitric oxide generation from neuronal nitric-oxide synthase
glycosaminoglycans modulate activation, activity, and stability of tripeptidyl-peptidase i in vitro and in vivo
-synuclein reduces proteasomal inhibition by -synuclein but not -synuclein
resistance exercise increases muscle protein synthesis and translation of eukaryotic initiation factor 2b mrna in a mammalian target of rapamycin-dependent manner
modulation of erythrocyte membrane mechanical function by protein 4.1 phosphorylation
a multifunctional lipoxygenase with fatty acid hydroperoxide cleaving activity from the moss physcomitrella patens
disruption of the mthfd1 gene reveals a monofunctional 10-formyltetrahydrofolate synthetase in mammalian mitochondria
characterization of the biochemical and transforming properties of the neuroepithelial transforming protein 1
inhibition of heparin-induced tau filament formation by phenothiazines, polyphenols, and porphyrins
rack1-mediated integration of adhesion and insulin-like growth factor i (igf-i) signaling and cell migration are defective in cells expressing an igf-i receptor mut..
tumor necrosis factor -dependent drug resistance to purine and pyrimidine analogues in human colon tumor cells mediated through ikk
yeast flavohemoglobin, a nitric oxide oxidoreductase, is located in both the cytosol and the mitochondrial matrix
the sv40 large t antigen contains a decoy phosphodegron that mediates its interactions with fbw7/hcdc4
role of the degree of oligomerization in the structure and function of human surfactant protein a
two heme binding sites are involved in the regulated degradation of the bacterial iron response regulator (irr) protein
evidence for the presence of three distinct binding sites for the thioflavin t class of alzheimer‘s disease pet imaging agents on -amyloid peptide fibrils
identification and integrative analysis of 28 novel genes specifically expressed and developmentally regulated in murine spermatogenic cells
b-myb represses elastin gene expression in aortic smooth muscle cells
transcription factor yb-1 mediates dna polymerase gene expression
real-time detection of basal and stimulated g protein gtpase activity using fluorescent gtp analogues
a clostridial endo--galactosidase that cleaves both blood group a and b glycotopes
phorbol 12-myristate 13-acetate induces epidermal growth factor receptor transactivation via protein kinase c/c-src pathways in glioblastoma cells
intracellular thiol-mediated modulation of epithelial sodium channel activity
ttk/hmps1 participates in the regulation of dna damage checkpoint response by phosphorylating chk2 on threonine 68
uncoupled packaging of amyloid precursor protein and presenilin 1 into coat protein complex ii vesicles
phosphoryl transfer step in the c-terminal src kinase controls src recognition
conserved n-terminal negative charges in the tim17 subunit of the tim23 translocase play a critical role in the import of preproteins into mitochondria
recruitment of the androgen receptor via serum response factor facilitates expression of a myogenic gene
high density lipoproteins facilitate hepatitis c virus entry through the scavenger receptor class b type i
the e46k mutation in -synuclein increases amyloid fibril formation
internalization and src activity regulate the time course of erk activation by delta opioid receptor ligands
in vitro molybdenum ligation to molybdopterin using purified components
actin cytoskeleton as the principal determinant of size-dependent dna mobility in cytoplasm
limiting effects of rip140 in estrogen signaling
last in, first out
the amyloid- peptide suppresses transforming growth factor-1-induced matrix metalloproteinase-2 production via smad7 expression in human monocytic thp-1 cells
saccharomyces cerevisiae mph1 gene, required for homologous recombination-mediated mutation avoidance, encodes a 3‘ to 5‘ dna helicase
the trifunctional sulfate-activating complex (sac) of mycobacterium tuberculosis
the saccharomyces cerevisiae peroxisomal import receptor pex5p is monoubiquitinated in wild type cells
expression of neutrophil gelatinase-associated lipocalin regulates epithelial morphogenesis in vitro
acquisition of unprecedented phosphatidylinositol 3,5-bisphosphate rise in hyperosmotically stressed 3t3-l1 adipocytes, mediated by arpikfyve-pikfyve pathway
reconstitution of a minimal dna replicase from pseudomonas aeruginosa and stimulation by non-cognate auxiliary factors
a small bacterial rna regulates a putative abc transporter
essential role of synoviolin in embryogenesis
epidermal and hepatocyte growth factors, but not keratinocyte growth factor, modulate protein kinase c translocation to the plasma membrane through 15(s)-hydroxyeic..
nmr analysis of the transient complex between membrane photosystem i and soluble cytochrome c6
two novel types of o-glycans on the mugwort pollen allergen art v 1 and their role in antibody binding
regulation of connexin43-protein binding in astrocytes in response to chemical ischemia/hypoxia
mass spectrometric analysis of the hiv-1 integrase-pyridoxal 5‘-phosphate complex reveals a new binding site for a nucleotide inhibitor
thrombomodulin changes the molecular surface of interaction and the rate of complex formation between thrombin and protein c
dro1, a gene down-regulated by oncogenes, mediates growth inhibition in colon and pancreatic cancer cells
essential interaction of egr-1 at an islet-specific response element for basal and gastrin-dependent glucagon gene transactivation in pancreatic -cells
inactivation of vhl by tumorigenic mutations that disrupt dynamic coupling of the pvhl·hypoxia-inducible transcription factor-1 complex
phosphodiesterase 4d forms a camp diffusion barrier at the apical membrane of the airway epithelium
integrin 64-erbb2 complex inhibits haptotaxis by up-regulating e-cadherin cell-cell junctions in keratinocytes
myotonic dystrophy protein kinase phosphorylates phospholamban and regulates calcium uptake in cardiomyocyte sarcoplasmic reticulum
kallikrein/kinin protects against myocardial apoptosis after ischemia/reperfusion via akt-glycogen synthase kinase-3 and akt-bad·14-3-3 signaling pathways
serum amyloid a binding to cla-1 (cd36 and limpii analogous-1) mediates serum amyloid a protein-induced activation of erk1/2 and p38 mitogen-activated protein kinases
-arrestin 1 and gq/11 coordinately activate rhoa and stress fiber formation following receptor stimulation
binding of rad51 and other peptide sequences to a promiscuous, highly electrostatic binding site in p53
the molecular mechanisms of coactivator utilization in ligand-dependent transactivation by the androgen receptor
functional demonstration of reverse transsulfuration in the mycobacterium tuberculosis complex reveals that methionine is the preferred sulfur source for pathogenic..
ultraviolet irradiation induces smad7 via induction of transcription factor ap-1 in human skin fibroblasts
spontaneous formation of nucleic acid-based nanoparticles is responsible for high interferon- induction by cpg-a in plasmacytoid dendritic cells
bone morphogenic protein-7 induces mesenchymal to epithelial transition in adult renal fibroblasts and facilitates regeneration of injured kidney
the role of mitogen-activated protein kinase phosphatase-1 in the response of alveolar macrophages to lipopolysaccharide
map1a light chain 2 interacts with exchange protein activated by cyclic amp 1 (epac1) to enhance rap1 gtpase activity and cell adhesion
col1a1 promoter-targeted expression of p20 ccaat enhancer-binding protein (c/ebp), a truncated c/ebp isoform, causes osteopenia in transgenic mice
human fas-associated factor 1 interacts with heat shock protein 70 and negatively regulates chaperone activity
the nociceptin pharmacophore site for opioid receptor binding derived from the nmr structure and bioactivity relationships
differential pattern of expression and sugar regulation of arabidopsis thaliana adp-glucose pyrophosphorylase-encoding genes
gln-trnagln formation from glu-trnagln requires cooperation of an asparaginase and a glu-trnagln kinase
epstein-barr virus lytic replication elicits atm checkpoint signal transduction while providing an s-phase-like cellular environment
analysis by fluorescence resonance energy transfer of the interaction between ligands and protein kinase c in the intact cell
the 8-kda dynein light chain binds to p53-binding protein 1 and mediates dna damage-induced p53 nuclear accumulation
crystal structure of the ptpl1/fap-1 human tyrosine phosphatase mutated in colorectal cancer
physical and functional interactions between stap-2/bks and stat5
residues within the first subdomain of the ferm-like domain in focal adhesion kinase are important in its regulation
periplakin interferes with g protein activation by the melanin-concentrating hormone receptor-1 by binding to the proximal segment of the receptor c-terminal tail
the ammonium transporter rhbg
integrin-dependent functions of the angiogenic inducer nov (ccn3)
oligomers of erbb3 have two distinct interfaces that differ in their sensitivity to disruption by heregulin
dissemination of lipid a deacylases (pagl) among gram-negative bacteria
identification of defensin 6 as a potential biomarker in colon adenocarcinoma
the structure of the complex of calmodulin with kar-
a novel endoplasmic reticulum membrane protein rcr1 regulates chitin deposition in the cell wall of saccharomyces cerevisiae
the nh2 terminus of influenza virus hemagglutinin-2 subunit peptides enhances the antitumor potency of polyarginine-mediated p53 protein transduction
peptide trapping of the holliday junction intermediate in cre-loxp site-specific recombination
the role of internalization in transforming growth factor 1-induced smad2 association with smad anchor for receptor activation (sara) and smad2-dependent signaling ..
evidence that the streptomyces developmental protein whid, a member of the whib family, binds a [4fe-4s] cluster
tenascin-r plays a role in neuroprotection via its distinct domains that coordinate to modulate the microglia function
dual function for a unique site within the 2i domain of integrin m2
deletion of mouse embryo fibroblast n-acetylglucosaminyltransferase v stimulates 51 integrin expression mediated by the protein kinase c signaling pathway
smad3 induces chondrogenesis through the activation of sox9 via creb-binding protein/p300 recruitment
myristoylated alanine-rich c kinase substrate-mediated neurotensin release via protein kinase c- downstream of the rho/rok pathway
structural and biochemical evidence for an enzymatic quinone redox cycle in escherichia coli
t cell receptor-induced activation of phospholipase c-1 depends on a sequence-independent function of the p-i region of slp-76
identification and characterization of a novel thioredoxin-related transmembrane protein of the endoplasmic reticulum
structural basis for phosphatidylinositol phosphate kinase type i binding to talin at focal adhesions
analysis of hiv-1 viral infectivity factor-mediated proteasome-dependent depletion of apobec3g
shp-2 modulates interleukin-1-induced ca2+ flux and erk activation via phosphorylation of phospholipase c1
structural and biochemical characterization of cib1 delineates a new family of ef-hand-containing proteins
single amino acid mutations in the cadherin receptor from heliothis virescens affect its toxin binding ability to cry1a toxins
calcium-dependent plasma membrane binding and cell lysis by perforin are mediated through its c2 domain
the high resolution crystal structure of a native thermostable serpin reveals the complex mechanism underpinning the stressed to relaxed transition
agonist-mediated conformational changes in acetylcholine-binding protein revealed by simulation and intrinsic tryptophan fluorescence
modulation of the actin cytoskeleton via gelsolin regulates vacuolar h+-atpase recycling
reversible mechanical unzipping of amyloid -fibrils
structure and substrate-binding mechanism of human ap4a hydrolase
human retroviral gag- and gag-pol-like proteins interact with the transforming growth factor- receptor activin receptor-like kinase 1
platelet-derived growth factor d, tissue-specific expression in the eye, and a key role in control of lens epithelial cell proliferation
epigen, the last ligand of erbb receptors, reveals intricate relationships between affinity and mitogenicity
side chain orientation of residues lining the selectivity filter of epithelial na+ channels
the promyelotic leukemia zinc finger promotes osteoblastic differentiation of human mesenchymal stem cells as an upstream regulator of cbfa1
doublecortin kinase-2, a novel doublecortin-related protein kinase associated with terminal segments of axons and dendrites
nte1p-mediated deacylation of phosphatidylcholine functionally interacts with sec14p
phosphorylation by mapk regulates simian immunodeficiency virus vpx protein nuclear import and virus infectivity
functional comparison of mouse slc26a6 anion exchanger with human slc26a6 polypeptide variants
expression of axin2 is regulated by the alternative 5‘-untranslated regions of its mrna
in vivo cleavage of 2,6-sialyltransferase by alzheimer -secretase
clac binds to amyloid peptides through the positively charged amino acid cluster within the collagenous domain 1 and inhibits formation of amyloid fibrils
induction of proinflammatory responses in macrophages by the glycosylphosphatidylinositols of plasmodium falciparum
conformational changes in the ligand-binding domain of a functional ionotropic glutamate receptor
silencing near trna genes requires nucleolar localization
thermodynamic, kinetic, and electron microscopy studies of concanavalin a and dioclea grandiflora lectin cross-linked with synthetic divalent carbohydrates
membrane transport proteins with complete replacement of transmembrane helices with polyalanine sequences remain functional
rev-erb regulates the expression of genes involved in lipid absorption in skeletal muscle cells
nitrile pathway involving acyl-coa synthetase
identification of a new membrane-associated protein that influences transport/maturation of gingipains and adhesins of porphyromonas gingivalis
nitric oxide scavenging by the cobalamin precursor cobinamide
expression and function of the nuclear factor of activated t cells in colon carcinoma cells
delayed dark adaptation in 11-cis-retinol dehydrogenase-deficient mice
parathyroid hormone-mediated regulation of na+-k+-atpase requires erk-dependent translocation of protein kinase c
carbon monoxide differentially modulates stat1 and stat3 and inhibits apoptosis via a phosphatidylinositol 3-kinase/akt and p38 kinase-dependent stat3 pathway durin..
regulation of cysteinyl leukotriene type 1 receptor internalization and signaling
characterization of the s-denitrosation activity of protein disulfide isomerase
expression of abcg5 and abcg8 is required for regulation of biliary cholesterol secretion
viral rna-directed rna polymerases use diverse mechanisms to promote recombination between rna molecules
indole-3-carbinol (i3c) inhibits cyclin-dependent kinase-2 function in human breast cancer cells by regulating the size distribution, associated cyclin e forms, and..
hiv-1 vif can directly inhibit apolipoprotein b mrna-editing enzyme catalytic polypeptide-like 3g-mediated cytidine deamination by using a single amino acid interac..
ca2+-calmodulin-dependent facilitation and ca2+ inactivation of ca2+ release-activated ca2+ channels
lactococcus lactis uses mscl as its principal mechanosensitive channel
two sur1-specific histidine residues mandatory for zinc-induced activation of the rat katp channel
consequences of lysine 72 mutation on the phosphorylation and activation state of camp-dependent kinase
nonsense suppression in yeast cells overproducing sup35 (erf3) is caused by its non-heritable amyloids
biosynthesis of hyaluronan
drip150 coactivation of estrogen receptor in zr-75 breast cancer cells is independent of lxxll motifs
expression of gastrointestinal glutathione peroxidase is inversely correlated to the presence of hepatitis c virus subgenomic rna in human liver cells
use of sulfated linked cyclitols as heparan sulfate mimetics to probe the heparin/heparan sulfate binding specificity of proteins
direct measurement of nitric oxide and oxygen partitioning into liposomes and low density lipoprotein
nuclear targeting and cell cycle regulatory function of human bard1
the acyl-amp ligase fadd32 and accd4-containing acyl-coa carboxylase are required for the synthesis of mycolic acids and essential for mycobacterial growth
hyaluronan constitutively regulates erbb2 phosphorylation and signaling complex formation in carcinoma cells
mislocalization or reduced expression of arf gtpase-activating protein asap1 inhibits cell spreading and migration by influencing arf1 gtpase cycling
the c terminus of ron tyrosine kinase plays an autoinhibitory role
contribution of mitochondrial dna repair to cell resistance from oxidative stress
functional comparison of human and drosophila hop reveals novel role in steroid receptor maturation
a unique sequence motif in the 54-kda subunit of the chloroplast signal recognition particle mediates binding to the 43-kda subunit
inhibition of src-like kinases reveals akt-dependent and -independent pathways in insulin-like growth factor i-mediated oligodendrocyte progenitor survival
the three nitric-oxide synthases differ in their kinetics of tetrahydrobiopterin radical formation, heme-dioxy reduction, and arginine hydroxylation
long lasting inhibition of adenylyl cyclase selectively mediated by inositol 1,4,5-trisphosphate-evoked calcium release
location of a common inhibitor binding site in the cytoplasmic vestibule of the cystic fibrosis transmembrane conductance regulator chloride channel pore
activation of µ-opioid receptors transfers control of g subunits to the regulator of g-protein signaling rgs9-
dynamic and differential in vivo modifications of the isoform hmga1a and hmga1b chromatin proteins
identification of mammalian proline transporter sit1 (slc6a20) with characteristics of classical system imino
signaling cascades activated upon antibody cross-linking of myelin oligodendrocyte glycoprotein
notch signaling represses myocardin-induced smooth muscle cell differentiation
hsp72 inhibits fas-mediated apoptosis upstream of the mitochondria in type ii cells
identification of v23rala-ser194 as a critical mediator for aurora-a-induced cellular motility and transformation by small pool expression screening
pancreatic -cell lipoprotein lipase independently regulates islet glucose metabolism and normal insulin secretion
probing the role of compartmentation of glycolysis in procyclic form trypanosoma brucei
kinetics of interconversion of ferrous enzymes, compound ii and compound iii, of wild-type synechocystis catalase-peroxidase and y249f
pram-1 potentiates arsenic trioxide-induced jnk activation
iron inactivates the rna polymerase ns5b and suppresses subgenomic replication of hepatitis c virus
the salmonella effector protein sopb protects epithelial cells from apoptosis by sustained activation of akt
neurons exclusively express n-bak, a bh3 domain-only bak isoform that promotes neuronal apoptosis
kinetics of fibril formation by polyalanine peptides
identification of t cell death-associated gene 8 (tdag8) as a novel acid sensing g-protein-coupled receptor
structural diversities of active site in clinical azole-bound forms between sterol 14-demethylases (cyp51s) from human and mycobacterium tuberculosis
the bacterial atpase seca functions as a monomer in protein translocation
genome-wide analysis reveals inositol, not choline, as the major effector of ino2p-ino4p and unfolded protein response target gene expression in yeast
extended dna binding site in pot1 broadens sequence specificity to allow recognition of heterogeneous fission yeast telomeres
calcium/calmodulin-dependent protein kinase ii (camkii) localization acts in concert with substrate targeting to create spatial restriction for phosphorylation
a novel tetraspanin fusion protein, peripherin-2, requires a region upstream of the fusion domain for activity
rdm1, a novel rna recognition motif (rrm)-containing protein involved in the cell response to cisplatin in vertebrates
two proteins homologous to the n- and c-terminal domains of the bacterial glycosyltransferase murg are required for the second step of dolichyl-linked oligosacchari..
the c-terminal domain of pediocin-like antimicrobial peptides (class iia bacteriocins) is involved in specific recognition of the c-terminal part of cognate immunit..
evidence for electron equilibrium between the two hemes bl in the dimeric cytochrome bc1 complex
interactions of tom1l1 with the multivesicular body sorting machinery
peroxisomal and mitochondrial oxidation of fatty acids in the heart, assessed from the 13c labeling of malonyl-coa and the acetyl moiety of citrate
bass hepcidin synthesis, solution structure, antimicrobial activities and synergism, and in vivo hepatic response to bacterial infections
anion-independent iron coordination by the campylobacter jejuni ferric binding protein
a key role for mast cell chymase in the activation of pro-matrix metalloprotease-9 and pro-matrix metalloprotease-2
novel function for receptor activity-modifying proteins (ramps) in post-endocytic receptor trafficking
direct inhibition of the interaction between -interaction domain and -interaction domain of voltage-dependent ca2+ channels by gem
presenilin-dependent processing and nuclear function of -protocadherins
pathogenic mutations located in the hydrophobic core of the prion protein interfere with folding and attachment of the glycosylphosphatidylinositol anchor
dicer is required for embryonic angiogenesis during mouse development
hypoxia-inducible factor-1-dependent overexpression of myeloid cell factor-1 protects hypoxic cells against tert-butyl hydroperoxide-induced apoptosis
isolation and characterization of griffithsin, a novel hiv-inactivating protein, from the red alga griffithsia sp.
role of interleukin-4 in regulation of age-related inflammatory changes in the hippocampus
regulation of zipper-interacting protein kinase activity in vitro and in vivo by multisite phosphorylation
deletion of the pdgfr- gene affects key fibroblast functions important for wound healing
hiv-1 tat interactions with p300 and pcaf transcriptional coactivators inhibit histone acetylation and neurotrophin signaling through creb
inhibition of yersinia tyrosine phosphatase by furanyl salicylate compounds
curcumin regulates expression and activity of matrix metalloproteinases 9 and 2 during prevention and healing of indomethacin-induced gastric ulcer
elevated pten levels account for the increased sensitivity of ethanol-exposed cells to tumor necrosis factor-induced cytotoxicity
ring finger ubiquitin-protein isopeptide ligase nrdp1/flrf regulates parkin stability and activity
discovery of pectin-degrading enzymes and directed evolution of a novel pectate lyase for processing cotton fabric
interaction of microtubule-associated protein-2 and p6
abnormal v(d)j recombination of t cell receptor locus in smar1 transgenic mice
spectral differentiation of blue opsins between phylogenetically close but ecologically distant goldfish and zebrafish
deficiency of atp2c1, a golgi ion pump, induces secretory pathway defects in endoplasmic reticulum (er)-associated degradation and sensitivity to er stress
linking of n-myc to death receptor machinery in neuroblastoma cells
gangliosides inhibit flagellin signaling in the absence of an effect on flagellin binding to toll-like receptor 5
pig-v involved in transferring the second mannose in glycosylphosphatidylinositol
lysophosphatidic acid (lpa) protects primary chronic lymphocytic leukemia cells from apoptosis through lpa receptor activation of the anti-apoptotic protein akt/pkb
constitutive activation of gsk3 down-regulates glycogen synthase abundance and glycogen deposition in rat skeletal muscle cells
peroxisome proliferator-activated receptor-/ inhibits epidermal cell proliferation by down-regulation of kinase activity
-arrestin binding to the 2-adrenergic receptor requires both receptor phosphorylation and receptor activation
early growth response factor-1 mediates prostaglandin e2-dependent transcriptional suppression of cytokine-induced tumor necrosis factor- gene expression in human m..
targeting a novel plasmodium falciparum purine recycling pathway with specific immucillins
archaeal cca-adding enzymes
structural basis of citrate-dependent and heparan sulfate-mediated cell surface retention of cobra cardiotoxin a3
x-ray structure of human prommp-
actinomycin d induces histone -h2ax foci and complex formation of -h2ax with ku70 and nuclear dna helicase ii
structure and dynamics of micelle-bound human -synuclein
peroxisome proliferator-activated receptor is a novel target of the nerve growth factor signaling pathway in pc12 cells
polymorphisms in human organic anion-transporting polypeptide 1a2 (oatp1a2)
the mouse cell surface protein toso regulates fas/fas ligand-induced apoptosis through its binding to fas-associated death domain
stage-by-stage change in dna methylation status of dnmt1 locus during mouse early development
stable plasma membrane levels of hctr1 mediate cellular copper uptake
the copper-transporting atpases, menkes and wilson disease proteins, have distinct roles in adult and developing cerebellum
characteristics of the polyamine transporter tpo1 and regulation of its activity and cellular localization by phosphorylation
structure of a cell polarity regulator, a complex between atypical pkc and par6 pb1 domains
molecular structure of human galactokinase
phosphoinositide binding by the disabled-1 ptb domain is necessary for membrane localization and reelin signal transduction
metal-catalyzed oxidation of -synuclein
physical and genetic interactions link the yeast protein zds1p with mrna nuclear export
identification of an extremely thermostable enzyme with dual sugar-1-phosphate nucleotidylyltransferase activities from an acidothermophilic archaeon, sulfolobus to..
mek1-dependent delayed expression of fos-related antigen-1 counteracts c-fos and p65 nf-b-mediated interleukin-8 transcription in response to cytokines or growth fa..
kruppel-like factor 4 abrogates myocardin-induced activation of smooth muscle gene expression
gpi7 is the second partner of pig-f and involved in modification of glycosylphosphatidylinositol
phosphorylation of carboxyl-terminal tyrosines modulates the specificity of sprouty-2 inhibition of different signaling pathways
molecular mechanism of inhibition of survivin transcription by the gc-rich sequence-selective dna binding antitumor agent, hedamycin
uteroglobin suppresses scca gene expression associated with allergic asthma
essential role of ib kinase in the constitutive processing of nf-b2 p100
the stress-inducted proteins rtp801 and rtp801l are negative regulators of the mammalian target of rapamycin pathway
-amylase is not required for breakdown of transitory starch in arabidopsis leaves
sirt1 shows no substrate specificity in vitro
transcriptional activation of the human gi2 gene promoter through nuclear factor-b and antioxidant response elements
restoration of growth to acidic phospholipid-deficient cells by dnaa(l366k) is independent of its capacity for nucleotide binding and exchange and requires dnaa
breakdown of 2-hydroxylated straight chain fatty acids via peroxisomal 2-hydroxyphytanoyl-coa lyase
a central role for the hsp90·cdc37 molecular chaperone module in interleukin-1 receptor-associated-kinase-dependent signaling by toll-like receptors
proteinase inhibition by proform of eosinophil major basic protein (pro-mbp) is a multistep process of intra- and intermolecular disulfide rearrangements
sphingosine 1-phosphate analogs as receptor antagonists
dual nature of the infectious prion protein revealed by high pressure
noncanonical dna elements in the lamin b2 origin of dna replication
depletion of mitochondrial dna causes impaired glucose utilization and insulin resistance in l6 glut4myc myocytes
heterologous expression, purification, and characterization of recombinant rat cysteine dioxygenase
translocation of diacylglycerol kinase from cytosol to plasma membrane in response to activation of g protein-coupled receptors and protein kinase c
the dna damage checkpoint response requires histone h2b ubiquitination by rad6-bre1 and h3 methylation by dot1
hepatocyte cyp2e1 overexpression and steatohepatitis lead to impaired hepatic insulin signaling
bioluminescence resonance energy transfer reveals ligand-induced conformational changes in cxcr4 homo- and heterodimers
vascular endothelial growth factor (vegf)-a165-induced prostacyclin synthesis requires the activation of vegf receptor-1 and -2 heterodimer
identification of a specific domain responsible for jnk22 autophosphorylation
nonequivalence of the nucleotide binding domains of the arsa atpase
the binding mechanism of the yeast f1-atpase inhibitory peptide
sumo-1 modification of human transcription factor (tf) iid complex subunits
marcks is a natively unfolded protein with an inaccessible actin-binding site
dna binding of repressor nuclear factor-b p50/p50 depends on phosphorylation of ser337 by the protein kinase a catalytic subunit
glucose deprivation increases mrna stability of vascular endothelial growth factor through activation of amp-activated protein kinase in du145 prostate carcinoma
matrix metalloproteinase secretion by gastric epithelial cells is regulated by e prostaglandins and mapks
the linker region joining the catalytic and the regulatory domains of cna is essential for binding to nfat
human s-nitroso oxymyoglobin is a store of vasoactive nitric oxide
interaction of insulin-like growth factor ii (igf-ii) with multiple plasma proteins
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