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免疫学杂志2006年第22期封面 购买


nucleic acid-sensing tlrs as modifiers of autoimmunity
cutting edge: cd4 is the receptor for the tick saliva immunosuppressor, salp15
cutting edge: activation of murine tlr8 by a combination of imidazoquinoline immune response modifiers and polyt oligodeoxynucleotides
cutting edge: resistance to hiv-1 infection among african female sex workers is associated with inhibitory kir in the absence of their hla ligands
cutting edge: inherent and acquired resistance to radiation-induced apoptosis in b cells: a pivotal role for stat3
cutting edge: the phosphoinositide 3-kinase p110 is critical for the function of cd4 + cd25 + foxp3 + regulatory t cells
cyclophosphamide-induced type-1 diabetes in the nod mouse is associated with a reduction of cd4 + cd25 + foxp3 + regulatory t cells
coreceptor signal strength regulates positive selection but does not determine cd4/cd8 lineage choice in a physiologic in vivo model
prime-boost with alternating dna vaccines designed to engage different antigen presentation pathways generates high frequencies of peptide-specific cd8 + t cells
antibody responses to mycobacterial and self heat shock protein 65 in autoimmune arthritis: epitope specificity and implication in pathogenesis
functional dichotomy in cd40 reciprocally regulates effector t cell functions
gata-3 regulates the development and function of invariant nkt cells
immature cd4 + cd8 + thymocytes and mature t cells regulate nur77 distinctly in response to tcr stimulation
specific and redundant roles for nfat transcription factors in the expression of mast cell-derived cytokines
partial versus full allogeneic hemopoietic chimerization is a preferential means to inhibit type 1 diabetes as the latter induces generalized immunosuppression
death of cd4 + t cells from lymph nodes during primary sivmac251 infection predicts the rate of aids progression
glutamate released by dendritic cells as a novel modulator of t cell activation
quantification of repertoire diversity of influenza-specific epitopes with predominant public or private tcr usage
cxc chemokine ligand 13 and cc chemokine ligand 19 cooperatively render resistance to apoptosis in b cell lineage acute and chronic lymphocytic leukemia cd23 + cd5 ..
e2-2 regulates the expansion of pro-b cells and follicular versus marginal zone decisions
human bone marrow: a reservoir for “enhanced effector memory“ cd8 + t cells with potent recall function
cd8 t cell recall responses are regulated by the tissue tropism of the memory cell and pathogen
cd4 + t cells in the absence of the cd8 + cytotoxic t cells are critical and sufficient for nkt cell-dependent tumor rejection
hepatitis c virus (hcv) core protein-induced, monocyte-mediated mechanisms of reduced ifn- and plasmacytoid dendritic cell loss in chronic hcv infection
melan-a/mart-1-specific cd4 t cells in melanoma patients: identification of new epitopes and ex vivo visualization of specific t cells by mhc class ii tetramers
t regulatory and primed uncommitted cd4 t cells express cd73, which suppresses effector cd4 t cells by converting 5‘-adenosine monophosphate to adenosine
activin a functions as a th2 cytokine in the promotion of the alternative activation of macrophages
the wild-type sequence (wt) p53 25-35 peptide induces hla-dr7 and hla-dr11-restricted cd4 + th cells capable of enhancing the ex vivo expansion and function of anti..
tcr genes direct mhc restriction in the potent human t cell response to a class i-bound viral epitope
fc receptor homolog 3 is a novel immunoregulatory marker of marginal zone and b1 b cells
adaptation of solitary intestinal lymphoid tissue in response to microbiota and chemokine receptor ccr7 signaling
tirc7 inhibits t cell proliferation by modulation of ctla-4 expression
microbial immune suppression mediated by direct engagement of inhibitory fc receptor
cd8 + il-17-producing t cells are important in effector functions for the elicitation of contact hypersensitivity responses
syk is downstream of intercellular adhesion molecule-1 and mediates human rhinovirus activation of p38 mapk in airway epithelial cells
a novel model of demyelinating encephalomyelitis induced by monocytes and dendritic cells
tlr4 up-regulation at protein or gene level is pathogenic for lupus-like autoimmune disease
functional interaction of common -chain and growth hormone receptor signaling apparatus
pertussis toxin is superior to tlr ligands in enhancing pathogenic autoimmunity, targeted at a neo-self antigen, by triggering robust expansion of th1 cells and the..
segregation of hla-c from icam-1 at nk cell immune synapses is controlled by its cell surface density
the study of high-affinity tcrs reveals duality in t cell recognition of antigen: specificity and degeneracy
double-negative t cells, activated by xenoantigen, lyse autologous b and t cells using a perforin/granzyme-dependent, fas-fas ligand-independent pathway
stages of germinal center transit are defined by b cell transcription factor coexpression and relative abundance
ccr8 expression identifies cd4 memory t cells enriched for foxp3 + regulatory and th2 effector lymphocytes
distinct molecular program imposed on cd4 + t cell targets by cd4 + cd25 + regulatory t cells
reversing tumor immune suppression with intratumoral il-12: activation of tumor-associated t effector/memory cells, induction of t suppressor apoptosis, and infiltr..
antibodies to complement receptor 3 treat established inflammation in murine models of colitis and a novel model of psoriasiform dermatitis
cd4 + cxcr4 high cd69 + t cells accumulate in lung adenocarcinoma
oligomerization of cxcl10 is necessary for endothelial cell presentation and in vivo activity
the peptidyl-prolyl isomerase pin1 regulates granulocyte-macrophage colony-stimulating factor mrna stability in t lymphocytes
v h replacement rescues progenitor b cells with two nonproductive vdj alleles
hla-b2704, an allotype associated with ankylosing spondylitis, is critically dependent on transporter associated with antigen processing and relatively independent ..
activating transcription factor/camp response element binding protein family member regulated transcription of cd1a
genes within the idd5 and idd9/11 diabetes susceptibility loci affect the pathogenic activity of b cells in nonobese diabetic mice
fine mapping of collagen-induced arthritis quantitative trait loci in an advanced intercross line
the immunosuppressant cyclosporin a antagonizes human formyl peptide receptor through inhibition of cognate ligand binding
tlr-dependent induction of ifn- mediates host defense against trypanosoma cruzi
adoptive transfer of cd8 + dendritic cells (dc) isolated from mice infected with chlamydia muridarum are more potent in inducing protective immunity than cd8 - dc
il-10 deficiency promotes increased borrelia burgdorferi clearance predominantly through enhanced innate immune responses
nk cell-derived ifn- differentially regulates innate resistance and neutrophil response in t cell-deficient hosts infected with mycobacterium tuberculosis
human cytomegalovirus envelope glycoproteins b and h are necessary for tlr2 activation in permissive cells
hiv induces maturation of monocyte-derived dendritic cells and langerhans cells
flavivirus activation of plasmacytoid dendritic cells delineates key elements of tlr7 signaling beyond endosomal recognition
sertoli cells initiate testicular innate immune responses through tlr activation
bordetella bronchiseptica modulates macrophage phenotype leading to the inhibition of cd4 + t cell proliferation and the initiation of a th17 immune response
prenatal malaria immune experience affects acquisition of plasmodium falciparum merozoite surface protein-1 invasion inhibitory antibodies during infancy
cytosolic localization of listeria monocytogenes triggers an early ifn- response by cd8 + t cells that correlates with innate resistance to infection
lipopolysaccharide-activated cd4 + cd25 + t regulatory cells inhibit neutrophil function and promote their apoptosis and death
airway epithelial cells produce b cell-activating factor of tnf family by an ifn- -dependent mechanism
il-1 and tnf- regulation of the adenosine receptor (a 2a ) expression: differential requirement for nf- b binding to the proximal promoter
extracellular heat shock protein-70 induces endotoxin tolerance in thp-1 cells
a jnk-independent signaling pathway regulates tnf -stimulated, c-jun-driven fra-1 protooncogene transcription in pulmonary epithelial cells
bruton?s tyrosine kinase is required for tlr-induced il-10 production
a novel role of hypoxia-inducible factor in cobalt chloride- and hypoxia-mediated expression of il-8 chemokine in human endothelial cells 1,
urothelial cd44 facilitates escherichia coli infection of the murine urinary tract
systemic inhibition of the angiotensin-converting enzyme limits lipopolysaccharide-induced lung neutrophil recruitment through both bradykinin and angiotensin ii-re..
metalloproteinases control brain inflammation induced by pertussis toxin in mice overexpressing the chemokine ccl2 in the central nervous system
chronic hyperglycemia predisposes to exaggerated inflammatory response and leukocyte dysfunction in akita mice
involvement of the purinergic p2x 7 receptor in the formation of multinucleated giant cells
complement-dependent p-selectin expression and injury following ischemic stroke
evidence of a functional role for mast cells in the development of type 1 diabetes mellitus in the biobreeding rat
fcr-bearing myeloid cells are responsible for triggering murine lupus nephritis
the chemokine decoy receptor m3 blocks cc chemokine ligand 2 and cxc chemokine ligand 13 function in vivo
transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: new molecules and patterns of gene expression
proteomic identification of in vivo substrates for matrix metalloproteinases 2 and 9 reveals a mechanism for resolution of inflammation
expression and functions of the vascular endothelial growth factors and their receptors in human basophils
inhibition of helicobacter hepaticus -induced colitis by il-10 requires the p50/p105 subunit of nf- b
major basic protein homolog (mbp2): a specific human eosinophil marker
induction of tolerance to innocuous inhaled antigen relies on a ccr7-dependent dendritic cell-mediated antigen transport to the bronchial lymph node
porcine endothelial cells and iliac arteries transduced with adenoil-4 are intrinsically protected, through akt activation, against immediate injury caused by human..
epitope specificity of autoreactive t and b cells associated with experimental autoimmune encephalomyelitis and optic neuritis induced by oligodendrocyte-specific p..
a single amino acid difference within the -2 domain of two naturally occurring equine mhc class i molecules alters the recognition of gag and rev epitopes by equine..
severe focal sialadenitis and dacryoadenitis in nzm2328 mice induced by mcmv: a novel model for human sjögren?s syndrome
cd4 + cd25 high t cells are enriched in the tumor and peripheral blood of prostate cancer patients
preservation of t cell proliferation restricted by protective hla alleles is critical for immune control of hiv-1 infection
atorvastatin restores lck expression and lipid raft-associated signaling in t cells from patients with systemic lupus erythematosus
role of mhc-linked genes in autoantigen selection and renal disease in a murine model of systemic lupus erythematosus
thrice-weekly low-dose rituximab decreases cd20 loss via shaving and promotes enhanced targeting in chronic lymphocytic leukemia
modulation of autoimmunity by tlr9 in the chronic graft-vs-host model of systemic lupus erythematosus
defective th1 cytokine gene transcription in cd4 + and cd8 + t cells from wiskott-aldrich syndrome patients
modulation of the immune response induced by gene electrotransfer of a hepatitis c virus dna vaccine in nonhuman primates
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