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免疫学杂志2004年第09期封面 购买


regulation and function of cyclin d2 in b lymphocyte subsets
cutting edge: 1,25-dihydroxyvitamin d 3 is a direct inducer of antimicrobial peptide gene expression
cutting edge: tnfr-associated factor (traf) 6 is essential for myd88-dependent pathway but not toll/il-1 receptor domain-containing adaptor-inducing ifn- (trif)-dep..
cutting edge: il-5 primes th2 cytokine-producing capacity in eosinophils through a stat5-dependent mechanism
cutting edge: regulation of cd8 + t cell effector population size
cutting edge: critical role for cd5 in experimental autoimmune encephalomyelitis: inhibition of engagement reverses disease in mice
cd30/cd30 ligand (cd153) interaction regulates cd4 + t cell-mediated graft-versus-host disease
cd4 + cd25 + cells controlling a pathogenic cd4 response inhibit cytokine differentiation, cxcr-3 expression, and tissue invasion
lymphocyte development and function in the absence of retinoic acid-related orphan receptor
lipid rafts mediate association of lfa-1 and cd3 and formation of the immunological synapse of ctl
presumptive lymph node organizers are differentially represented in developing mesenteric and peripheral nodes
caspase-8 serves both apoptotic and nonapoptotic roles
phosphatidylserine regulates the maturation of human dendritic cells
a novel mutation in cd83 results in the development of a unique population of cd4 + t cells
4-1bb and ox40 dual costimulation synergistically stimulate primary specific cd8 t cells for robust effector function
constitutive expression of ccr7 directs effector cd8 t cells into the splenic white pulp and impairs functional activity
bcl-2 transduction protects human endothelial cell synthetic microvessel grafts from allogeneic t cells in vivo
vascular endothelium does not activate cd4 + direct allorecognition in graft rejection
characterization of the systemic loss of dendritic cells in murine lymph nodes during polymicrobial sepsis 1,
opsonization with c1q and mannose-binding lectin targets apoptotic cells to dendritic cells
identification and characterization of pdc-like cells in normal mouse skin and melanomas treated with imiquimod
strong and durable tcr clustering at the t/dendritic cell immune synapse is not required for nfat activation and ifn- production in human cd4 + t cells 1,
an evaluation of enforced rapid proteasomal degradation as a means of enhancing vaccine-induced ctl responses
functional maturation of cd4 + cd25 + ctla4 + cd45ra + t regulatory cells in human neonatal t cell responses to environmental antigens/allergens
p21 cip1 and p27 kip1 act in synergy to alter the sensitivity of naive t cells to tgf- -mediated g 1 arrest through modulation of il-2 responsiveness
diabetes incidence is unaltered in glutamate decarboxylase 65-specific tcr retrogenic nonobese diabetic mice: generation by retroviral-mediated stem cell gene trans..
prevention of diabetes in nonobese diabetic mice mediated by cd1d-restricted nonclassical nkt cells
cd4 + cd25 bright t cells in human intestinal lamina propria as regulatory cells
proliferation and differentiation of cd8 + t cells in the absence of il-2/15 receptor -chain expression or stat5 activation
functional and genetic analysis of two cd8 t cell subsets defined by the level of cd45rc expression in the rat
size-dependent immunogenicity: therapeutic and protective properties of nano-vaccines against tumors
il-15r is a negative regulator of tcr-activated proliferation in cd4 + t cells
environmental and endogenous peroxisome proliferator-activated receptor agonists induce bone marrow b cell growth arrest and apoptosis: interactions between mono(2-..
fas-mediated inhibition of cd4 + t cell priming results in dominance of type 1 cd8 + t cells in the immune response to the contact sensitizer trinitrophenyl
folate deficiency inhibits the proliferation of primary human cd8 + t lymphocytes in vitro
ceramide inhibits il-2 production by preventing protein kinase c-dependent nf- b activation: possible role in protein kinase c regulation
naive t cells are resistant to anergy induction by anti-cd3 antibodies
vav-dependent and vav-independent phosphatidylinositol 3-kinase activation in murine b cells determined by the nature of the stimulus
functional analysis of -571 il-10 promoter polymorphism reveals a repressor element controlled by sp1
single-stranded dna breaks adjacent to cytosines occur during ig gene class switch recombination
the complete map of the ig heavy chain constant gene region reveals evidence for seven igg isotypes and for igd in the horse 1,
the chemoattractants, il-8 and formyl-methionyl-leucyl-phenylalanine, regulate granulocyte colony-stimulating factor signaling by inducing suppressor of cytokine si..
targeted deletion of protein kinase c reveals a distribution of functions between the two atypical protein kinase c isoforms
rates of recombination and chain pair biases greatly influence the primary tcr repertoire in the thymus of adult mice
dissecting mhc class ii export, b cell maturation, and dm stability defects in invariant chain mutant mice
arthropod-derived histamine-binding protein prevents murine allergic asthma
ccr5-deficient mice control mycobacterium tuberculosis infection despite increased pulmonary lymphocytic infiltration
inhibition of lipopolysaccharide-induced macrophage il-12 production by leishmania mexicana amastigotes: the role of cysteine peptidases and the nf- b signaling pat..
tgf- receptor signaling is critical for mucosal iga responses
the cholera toxin-derived cta1-dd vaccine adjuvant administered intranasally does not cause inflammation or accumulate in the nervous tissues
signaling of apoptosis through tlrs critically involves toll/il-1 receptor domain-containing adapter inducing ifn-, but not myd88, in bacteria-infected murine macro..
coinfection modulates inflammatory responses and clinical outcome of helicobacter felis and toxoplasma gondii infections
intracellularly expressed tlr2s and tlr4s contribution to an immunosilent environment at the ocular mucosal epithelium
vaccine-induced immunity against helicobacter pylori infection is impaired in il-18-deficient mice
nk cells use perforin rather than granulysin for anticryptococcal activity
inhibition of the growth of toxoplasma gondii in immature human dendritic cells is dependent on the expression of tnf- receptor 2
a novel recombinant multisubunit vaccine against chlamydia
shaping phenotype, function, and survival of dendritic cells by cytomegalovirus-encoded il-10
il-6 and il-10 induction from dendritic cells in response to mycobacterium tuberculosis is predominantly dependent on tlr2-mediated recognition
inhibition of myeloid dendritic cell accessory cell function and induction of t cell anergy by alcohol correlates with decreased il-12 production 1,
prolonged production of tnf- exacerbates illness during respiratory syncytial virus infection
expression of a functional c5a receptor in regenerating hepatocytes and its involvement in a proliferative signaling pathway in rat
regulation of found in inflammatory zone 1 expression in bleomycin-induced lung fibrosis: role of il-4/il-13 and mediation via stat-6
vitamin d receptor-deficient mice fail to develop experimental allergic asthma
c5a initiates the inflammatory cascade in immune complex peritonitis
a critical regulatory role of leucin zipper transcription factor c-maf in th1-mediated experimental colitis
n -nonanoyl-cc chemokine ligand 14, a potent cc chemokine ligand 14 analogue that prevents the recruitment of eosinophils in allergic airway inflammation
nrf2 is a key transcription factor that regulates antioxidant defense in macrophages and epithelial cells: protecting against the proinflammatory and oxidizing effe..
il-17 markedly up-regulates -defensin-2 expression in human airway epithelium via jak and nf- b signaling pathways
presence of ifn- does not indicate its necessity for induction of coronary arteritis in an animal model of kawasaki disease
15-deoxy- 12,14 -prostaglandin j 2 inhibits ifn-inducible protein 10/cxc chemokine ligand 10 expression in human microglia: mechanisms and implications
short- and long-term effects of il-1 and tnf antagonists on periodontal wound healing
mechanism of action of transmembrane activator and calcium modulator ligand interactor-ig in murine systemic lupus erythematosus
c protein-induced myocarditis and subsequent dilated cardiomyopathy: rescue from death and prevention of dilated cardiomyopathy by chemokine receptor dna therapy
ig-reactive cd4 + cd25 + t cells from tolerized (new zealand black x new zealand white)f 1 mice suppress in vitro production of antibodies to dna
frequent joining of bcl-2 to a j h 6 gene in hepatitis c virus-associated t(14;18)
cyclic adenosine 5‘-monophosphate response element modulator is responsible for the decreased expression of c- fos and activator protein-1 binding in t cells from ..
synovial fibroblasts from patients with rheumatoid arthritis, like fibroblasts from graves disease, express high levels of il-16 when treated with igs against insul..
thy-1: more than a mouse pan-t cell marker
cutting edge: direct interaction of tlr4 with nad(p)h oxidase 4 isozyme is essential for lipopolysaccharide-induced production of reactive oxygen species and activa..
cutting edge: murine dendritic cells require il-15r to prime nk cells
cutting edge: serotonin is a chemotactic factor for eosinophils and functions additively with eotaxin
stromelysin-2 (matrix metalloproteinase 10) is inducible in lymphoma cells and accelerates the growth of lymphoid tumors in vivo
adoptive transfer of paternal antigen-hyporesponsive t cells induces maternal tolerance to the allogeneic fetus in abortion-prone matings
kinetics of in vivo elimination of suicide gene-expressing t cells affects engraftment, graft-versus-host disease, and graft-versus-leukemia after allogeneic bone m..
b7-2 (cd86) controls the priming of autoreactive cd4 t cell response against pancreatic islets
dynamic redistribution of the activating 2b4/sap complex at the cytotoxic nk cell immune synapse
immunological synapse formation licenses cd40-cd40l accumulations at t-apc contact sites
lfa-1 contributes an early signal for nk cell cytotoxicity
fas-fas ligand interactions are essential for the binding to and killing of activated macrophages by t cells
cc chemokine ligands 25 and 28 play essential roles in intestinal extravasation of iga antibody-secreting cells
nitric oxide-dependent mitochondrial biogenesis generates ca 2+ signaling profile of lupus t cells
cd59a is the primary regulator of membrane attack complex assembly in the mouse
quantitative and qualitative differences in the in vivo response of nkt cells to distinct - and -anomeric glycolipids
differential requirement for tapasin in the presentation of leader- and insulin-derived peptide antigens to qa-1 b -restricted ctls
cross-talk between activated human nk cells and cd4 + t cells via ox40-ox40 ligand interactions
stimulatory killer ig-like receptors modulate t cell activation through dap12-dependent and dap12-independent mechanisms
the critical role of residues 43 r and 44 q of carcinoembryonic antigen cell adhesion molecules-1 in the protection from killing by human nk cells
a dual role of ifn- in the balance between proliferation and death of human cd4 + t lymphocytes during primary response
murine plasmacytoid dendritic cells initiate the immunosuppressive pathway of tryptophan catabolism in response to cd200 receptor engagement
intratumoral cc chemokine ligand 5 overexpression delays tumor growth and increases tumor cell infiltration
discrete event modeling of cd4 + memory t cell generation
expansion and function of cd8 + t cells expressing ly49 inhibitory receptors specific for mhc class i molecules
sphingosine contributes to glucocorticoid-induced apoptosis of thymocytes independently of the mitochondrial pathway 1,
enhanced pathogenicity of diabetogenic t cells escaping a non-mhc gene-controlled near death experience
a role for the granzyme b inhibitor serine protease inhibitor 6 in cd8 + memory cell homeostasis
enhanced responses of glycosylphosphatidylinositol anchor-deficient t lymphocytes
expression of the glucocorticoid receptor from the 1a promoter correlates with t lymphocyte sensitivity to glucocorticoid-induced cell death
human galectin-2: novel inducer of t cell apoptosis with distinct profile of caspase activation
hiv-1 tat protein modulates the generation of cytotoxic t cell epitopes by modifying proteasome composition and enzymatic activity
il-6 regulates in vivo dendritic cell differentiation through stat3 activation
cd8 t cell responses to lymphocytic choriomeningitis virus in early growth response gene 1-deficient mice
impaired type i ifn-induced jak/stat signaling in fa-c cells and abnormal cd4 + th cell subsets in fancc -/- mice
an indispensable role for stat1 in il-27-induced t-bet expression but not proliferation of naive cd4 + t cells
unraveling the consecutive recombination events in the human igk locus
dual function of the extracellular matrix: stimulatory for cell cycle progression of naive t cells and antiapoptotic for tissue-derived memory t cells
signaling through cd70 regulates b cell activation and igg production
a role for cd28 in lymphopenia-induced proliferation of cd4 t cells
microglia initiate central nervous system innate and adaptive immune responses through multiple tlrs
immunoproteasomes down-regulate presentation of a subdominant t cell epitope from lymphocytic choriomeningitis virus
analysis of notch1 function by in vitro t cell differentiation of pax5 mutant lymphoid progenitors
delta-short consensus repeat 4-decay accelerating factor (daf: cd55) inhibits complement-mediated cytolysis but not nk cell-mediated cytolysis
the murine nk receptor 2b4 (cd244) exhibits inhibitory function independent of signaling lymphocytic activation molecule-associated protein expression
phosphorylation of grb2-associated binder 2 on serine 623 by erk mapk regulates its association with the phosphatase shp-2 and decreases stat5 activation
the binding sites for competitive antagonistic, allosteric antagonistic, and agonistic antibodies to the i domain of integrin lfa-1
histone deacetylase 3, a class i histone deacetylase, suppresses mapk11-mediated activating transcription factor-2 activation and represses tnf gene expression
characterization of a dipeptide motif regulating ifn- receptor 2 plasma membrane accumulation and ifn- responsiveness
a novel mutation in ifn- receptor 2 with dominant negative activity: biological consequences of homozygous and heterozygous states
distinct and opposite activities of human terminal deoxynucleotidyltransferase splice variants
il-13 activates a mechanism of tissue fibrosis that is completely tgf- independent
mechanisms of host defense following severe acute respiratory syndrome-coronavirus (sars-cov) pulmonary infection of mice
il-12p40 and il-18 modulate inflammatory and immune responses to respiratory syncytial virus infection
identification of immunodominant sites on the spike protein of severe acute respiratory syndrome (sars) coronavirus: implication for developing sars diagnostics and..
salmonella escape from antigen presentation can be overcome by targeting bacteria to fc receptors on dendritic cells
hemozoin (malarial pigment) inhibits differentiation and maturation of human monocyte-derived dendritic cells: a peroxisome proliferator-activated receptor- -mediat..
stat4 is a critical mediator of early innate immune responses against pulmonary klebsiella infection
the development of functional cd8 t cell memory after listeria monocytogenes infection is not dependent on cd40
low-dose salmonella infection evades activation of flagellin-specific cd4 t cells
protection against late-onset aids in macaques prophylactically immunized with a live simian hiv vaccine was dependent on persistence of the vaccine virus
herpes simplex virus type-1-induced activation of myeloid dendritic cells: the roles of virus cell interaction and paracrine type i ifn secretion
activation of signaling lymphocytic activation molecule triggers a signaling cascade that enhances th1 responses in human intracellular infection
platelet-derived thrombospondin-1 is necessary for the vitamin d-binding protein (gc-globulin) to function as a chemotactic cofactor for c5a
the essential role of the intestinal microbiota in facilitating acute inflammatory responses
reduction of nitric oxide synthase 2 expression by distamycin a improves survival from endotoxemia
regulation of human polymorphonuclear leukocytes functions by the neuropeptide pituitary adenylate cyclase-activating polypeptide after activation of mapks
cigarette smoke inhibits lipopolysaccharide-induced production of inflammatory cytokines by suppressing the activation of activator protein-1 in bronchial epithelia..
modulation of renal disease in mrl/ lpr mice by suberoylanilide hydroxamic acid
proinflammatory cytokines induce proteinase 3 as membrane-bound and secretory forms in human oral epithelial cells and antibodies to proteinase 3 activate the cells..
renal expression of the c3a receptor and functional responses of primary human proximal tubular epithelial cells
il-8 is a key chemokine regulating neutrophil recruitment in a new mouse model of shigella- induced colitis
andrographolide attenuates inflammation by inhibition of nf- b activation through covalent modification of reduced cysteine 62 of p50
cd137-deficient mice have reduced nk/nkt cell numbers and function, are resistant to lipopolysaccharide-induced shock syndromes, and have lower il-4 responses
accelerated ischemia/reperfusion-induced injury in autoimmunity-prone mice 1,
complement mediates the binding of hiv to erythrocytes
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