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免疫学杂志2004年第03期封面 购买


of mice and not men: differences between mouse and human immunology
cutting edge: activation of toll-like receptor 2 induces a th2 immune response and promotes experimental asthma
cutting edge: activity of human adult microglia in response to cc chemokine ligand 21
cutting edge: a new approach to modeling early lung immunity in murine tuberculosis
phosphatidylinositol 3-kinase-dependent mitogen-activated protein/extracellular signal-regulated kinase kinase 1/2 and nf- b signaling pathways are required for b c..
a role for il-10-mediated hla-dr7-restricted t cell-dependent events in development of the modified th2 response to cat allergen
human thymus exports naive cd8 t cells that can home to nonlymphoid tissues
cd86 and cd80 differentially modulate the suppressive function of human regulatory t cells
the centromeric region of chromosome 7 from mrl mice ( lmb3 ) is an epistatic modifier of fas for autoimmune disease expression
the t cells specific for the carboxyl-terminal determinants of self (rat) heat-shock protein 65 escape tolerance induction and are involved in regulation of autoimm..
transgenic expression of insulin receptor substrate 2 in murine b cells alters the cell density-dependence of ige production in vitro and enhances ige production in..
circadian rhythms of granzyme b, perforin, ifn-, and nk cell cytolytic activity in the spleen: effects of chronic ethanol
il-12 priming during in vitro antigenic stimulation changes properties of cd8 t cells and increases generation of effector and memory cells
compromised humoral and delayed-type hypersensitivity responses in il-23-deficient mice
cd4 t cell-dependent cd8 t cell maturation
mannose receptor targeting of tumor antigen pmel17 to human dendritic cells directs anti-melanoma t cell responses via multiple hla molecules
depletion of cxcr2 inhibits tumor growth and angiogenesis in a murine model of lung cancer
lassa virus infection of human dendritic cells and macrophages is productive but fails to activate cells
in vivo v l -targeted activation-induced apoptotic supraclonal deletion by a microbial b cell toxin
analysis of autoreactive cd4 t cells in experimental autoimmune encephalomyelitis after primary and secondary challenge using mhc class ii tetramers
a role for toll-like receptor 4 in dendritic cell activation and cytolytic cd8 + t cell differentiation in response to a recombinant heat shock fusion protein
different potentials of t cell subsets in regulating airway responsiveness: v 1 + cells, but not v 4 + cells, promote airway hyperreactivity, th2 cytokines, and air..
a novel anti-inflammatory role of simvastatin in a murine model of allergic asthma
il-12 inhibits thymic involution by enhancing il-7- and il-2-induced thymocyte proliferation
spontaneous organ-specific th2-mediated autoimmunity in tcr transgenic mice
differential segmental flexibility and reach dictate the antigen binding mode of chimeric igd and igm: implications for the function of the b cell receptor
posttranscriptional inhibition of gene expression by mycobacterium tuberculosis offsets transcriptional synergism with ifn- and posttranscriptional up-regulation by..
toward a definition of self: proteomic evaluation of the class i peptide repertoire
a regulatory role for cd37 in t cell proliferation
all known in vivo functions of the oct-2 transcription factor require the c-terminal protein domain
relevance of posttranslational modifications for the arthritogenicity of type ii collagen
the ig-like domain of tapasin influences intermolecular interactions
physical and functional interactions between daxx and dna methyltransferase 1-associated protein, dmap1
a peptide that antagonizes tcr-mediated reactions with both syngeneic and allogeneic agonists: functional and structural aspects
toxoplasma gondii interferes with lipopolysaccharide-induced mitogen-activated protein kinase activation by mechanisms distinct from endotoxin tolerance
a type i ifn-dependent pathway induced by schistosoma mansoni eggs in mouse myeloid dendritic cells generates an inflammatory signature
essential involvement of ifn- in clostridium difficile toxin a-induced enteritis
targeting of secretory iga to peyers patch dendritic and t cells after transport by intestinal m cells
nk cells, but not nkt cells, are involved in pseudomonas aeruginosa exotoxin a-induced hepatotoxicity in mice
the classical activation pathway of the human complement system is specifically inhibited by calreticulin from trypanosoma cruzi
role of nicotinamide adenine dinucleotide phosphate oxidase 1 in oxidative burst response to toll-like receptor 5 signaling in large intestinal epithelial cells
the contribution of the toll-like/il-1 receptor superfamily to innate and adaptive immunity to fungal pathogens in vivo
postsecretory processing generates multiple cathelicidins for enhanced topical antimicrobial defense
t cell reactivity during infectious mononucleosis and persistent gammaherpesvirus infection in mice
leishmania infantum promotes replication of hiv type 1 in human lymphoid tissue cultured ex vivo by inducing secretion of the proinflammatory cytokines tnf- and il-1
enhanced cd8 + t cell immune responses and protection elicited against plasmodium berghei malaria by prime boost immunization regimens using a novel attenuated fowl..
hemozoin-inducible proinflammatory events in vivo: potential role in malaria infection
the group b streptococcal and pneumococcal hic proteins are structurally related immune evasion molecules that bind the complement inhibitor factor h in an analogou..
coordinate expression of cytokines and chemokines by nk cells during murine cytomegalovirus infection
toll-like receptor 2 plays a role in the early inflammatory response to murine pneumococcal pneumonia but does not contribute to antibacterial defense
comprehensive early and lasting loss of memory cd8 t cells and functional memory during acute and persistent viral infections
very diverse cd8 t cell clonotypic responses after virus infections
the pathogenesis of schistosomiasis is controlled by cooperating il-10-producing innate effector and regulatory t cells
depletion of cd4 + t cells during immunization with nonviable listeria monocytogenes causes enhanced cd8 + t cell-mediated protection against listeriosis
the effect of innate immunity on autoimmune diabetes and the expression of toll-like receptors on pancreatic islets
il-10 inhibits fc ri expression in mouse mast cells
hiv-infected lymphocytes regulate fibronectin synthesis by tgf 1 secretion
acidosis improves uptake of antigens and mhc class i-restricted presentation by dendritic cells
cd40 on adult human airway epithelial cells: expression and proinflammatory effects
recruitment of ifn- -producing (th1-like) cells into the inflamed retina in vivo is preferentially regulated by p-selectin glycoprotein ligand 1:p/e-selectin intera..
cryptic epitope identified in rat and human cardiac myosin s2 region induces myocarditis in the lewis rat
direct in vivo monitoring of acute allergic reactions in human conjunctiva
long-term suppression of tumor growth by tnf requires a stat1- and ifn regulatory factor 1-dependent ifn- pathway but not il-12 or il-18
grass pollen immunotherapy induces mucosal and peripheral il-10 responses and blocking igg activity
persistent and selective deficiency of cd4 + t cell immunity to cytomegalovirus in immunocompetent young children
lymphoma b cells evade apoptosis through the tnf family members baff/blys and april
rituximab infusion promotes rapid complement depletion and acute cd20 loss in chronic lymphocytic leukemia
vaccine-induced cd4 + t cell responses to mage-3 protein in lung cancer patients
role of specific cd8 + t cells in the severity of a fulminant zoonotic viral hemorrhagic fever, hantavirus pulmonary syndrome
human memory b cells transferred by allogenic bone marrow transplantation contribute significantly to the antibody repertoire of the recipient
molecular and immunological evaluation of the transcription factor sox-4 as a lung tumor vaccine antigen
host conditioning is a primary determinant in modulating the effect of il-7 on murine graft-versus-host disease
effects of sustained hiv-1 plasma viremia on hiv-1 gag-specific cd4 + t cell maturation and function
textbook germinal centers?
cutting edge: myeloid differentiation factor 88 is essential for pulmonary host defense against pseudomonas aeruginosa but not staphylococcus aureus
cutting edge: dgyw/wrch is a better predictor of mutability at g:c bases in ig hypermutation than the widely accepted rgyw/wrcy motif and probably reflects a two-st..
cutting edge: long-lived cd8 memory and protective immunity in the absence of cd40 expression on cd8 t cells
suppression of cd4 + t lymphocyte effector functions by cd4 + cd25 + cells in vivo
glu 496 to ala polymorphism in the p2x 7 receptor impairs atp-induced il-1 release from human monocytes
murine cd93 (c1qrp) contributes to the removal of apoptotic cells in vivo but is not required for c1q-mediated enhancement of phagocytosis
myeloid differentiation factor 88 is required for cross-priming in vivo
distinct profiles of human b cell effector cytokines: a role in immune regulation?
ech, an epoxycyclohexenone derivative that specifically inhibits fas ligand-dependent apoptosis in ctl-mediated cytotoxicity
age-related impaired type 1 t cell responses to influenza: reduced activation ex vivo, decreased expansion in ctl culture in vitro, and blunted response to influenz..
selection of similar naive t cell repertoires but induction of distinct t cell responses by native and modified antigen
cd1d1-dependent control of the magnitude of an acute antiviral immune response
memory t cells originate from adoptively transferred effectors and reconstituting host cells after sequential lymphodepletion and adoptive immunotherapy
indirect minor histocompatibility antigen presentation by allograft recipient cells in the draining lymph node leads to the activation and clonal expansion of cd4 +..
degradation of nf- b in t cells by gangliosides expressed on renal cell carcinomas
prolonged antigen presentation, apc-, and cd8 + t cell turnover during mycobacterial infection: comparison with listeria monocytogenes
improved immunogenicity of an immunodominant epitope of the her-2/neu protooncogene by alterations of mhc contact residues
distinct sequences in the cytoplasmic domain of complement receptor 2 are involved in antigen internalization and presentation
the rat rt1-a1 c mhc molecule is a xenogeneic ligand recognized by the mouse activating ly-49w and inhibitory ly-49g receptors
a late, prolonged activation of the phosphatidylinositol 3-kinase pathway is required for t cell proliferation
carcinoembryonic antigen-related cellular adhesion molecule 1 isoforms alternatively inhibit and costimulate human t cell function
the cell-cell adhesion molecule carcinoembryonic antigen-related cellular adhesion molecule 1 inhibits il-2 production and proliferation in human t cells by associa..
heme oxygenase-1 modulates the expression of adhesion molecules associated with endothelial cell activation
b cell receptors and complement receptors target the antigen to distinct intracellular compartments
a keratinocyte-responsive tcr is necessary for dendritic epidermal t cell activation by damaged keratinocytes and maintenance in the epidermis
distinct roles for the ox40-ox40 ligand interaction in regulatory and nonregulatory t cells
hyperproduction of proinflammatory cytokines by wsx-1-deficient nkt cells in concanavalin a-induced hepatitis
inhibition of nfat specifically in t cells prevents allergic pulmonary inflammation
glycoprotein 170 induces platelet-activating factor receptor membrane expression and confers tumor cell hypersensitivity to nk-dependent cell lysis
nasal flt3 ligand cdna elicits cd11c + cd8 + dendritic cells for enhanced mucosal immunity
b cells are crucial for both development and maintenance of the splenic marginal zone
defective b1 cell homing to the peritoneal cavity and preferential recruitment of b1 cells in the target organs in a murine model for systemic lupus erythematosus
the 2 -microglobulin locus of rainbow trout ( oncorhynchus mykiss ) contains three polymorphic genes
a major allergen from pollen defines a novel family of plant proteins and shows intra- and interspecie cross-reactivity
demethylation of promoter regulatory elements contributes to perforin overexpression in cd4 + lupus t cells
architectural changes in the tcr:cd3 complex induced by mhc:peptide ligation
unexpected diversity in the fine specificity of monoclonal antibodies that use the same v region gene to glucuronoxylomannan of cryptococcus neoformans
a disintegrin and metalloproteinase 10-mediated cleavage and shedding regulates the cell surface expression of cxc chemokine ligand 1
production of il-12 by macrophages infected with toxoplasma gondii depends on the parasite genotype
lipopolysaccharide from coxiella burnetii is involved in bacterial phagocytosis, filamentous actin reorganization, and inflammatory responses through toll-like rece..
t cell-intrinsic expression of c-rel regulates th1 cell responses essential for resistance to toxoplasma gondii
toll-like receptor 2 suppresses immunity against candida albicans through induction of il-10 and regulatory t cells
concomitant helper response rescues otherwise low avidity cd8 + memory ctls to become efficient effectors in vivo
increased dendritic cell numbers impair protective immunity to intracellular bacteria despite augmenting antigen-specific cd8 + t lymphocyte responses
mice transgenic for il-1 receptor antagonist protein are resistant to herpetic stromal keratitis: possible role for il-1 in herpetic stromal keratitis pathogenesis
control of simian/human immunodeficiency virus viremia and disease progression after il-2-augmented dna-modified vaccinia virus ankara nasal vaccination in nonhuman..
the human cationic peptide ll-37 induces activation of the extracellular signal-regulated kinase and p38 kinase pathways in primary human monocytes
cercarial dermatitis caused by bird schistosomes comprises both immediate and late phase cutaneous hypersensitivity reactions
il-4 and il-13 up-regulate intestinal trefoil factor expression: requirement for stat6 and de novo protein synthesis
mannose-binding lectin binds to two major outer membrane proteins, opacity protein and porin, of neisseria meningitidis
vaccination with phosphoglycan-deficient leishmania major protects highly susceptible mice from virulent challenge without inducing a strong th1 response
streptococcal m5 protein prevents neutrophil phagocytosis by interfering with cd11b/cd18 receptor-mediated association and signaling
diesel exhaust particles suppress in vivo ifn- production by inhibiting cytokine effects on nk and nkt cells
aberrant toll receptor expression and endotoxin hypersensitivity in mice lacking a functional tgf- 1 signaling pathway
activation of the d prostanoid receptor 1 regulates immune and skin allergic responses
cell surface localization of heparanase on macrophages regulates degradation of extracellular matrix heparan sulfate
decay-accelerating factor deficiency increases susceptibility to dextran sulfate sodium-induced colitis: role for complement in inflammatory bowel disease
cd4 + cd25 + t cells regulate airway eosinophilic inflammation by modulating the th2 cell phenotype
human thy-1 (cd90) on activated endothelial cells is a counterreceptor for the leukocyte integrin mac-1 (cd11b/cd18)
cxcr2 is critical to hyperoxia-induced lung injury
critical protection from renal ischemia reperfusion injury by cd55 and cd59
expression of developmental endothelial locus-1 in a subset of macrophages for engulfment of apoptotic cells
t cell recognition of desmoglein 3 peptides in patients with pemphigus vulgaris and healthy individuals
expansion and functional relevance of high-avidity myelin-specific cd4 + t cells in multiple sclerosis
impairment of il-12-dependent stat4 nuclear translocation in a patient with recurrent mycobacterium avium infection
enrichment of anti-glomerular antigen antibody-producing cells in the kidneys of mrl/mpj-fas lpr mice
survivin enhances fas ligand expression via up-regulation of specificity protein 1-mediated gene transcription in colon cancer cells
targeted bioactivity of membrane-anchored tnf by an antibody-derived tnf fusion protein
cloned human tcr from patients with autoimmune disease can respond to two structurally distinct autoantigens
immune defects in 28-kda proteasome activator -deficient mice
hla-dq8-associated t cell responses to the diabetes autoantigen phogrin (ia-2 ) in human prediabetes
il-2 production by virus- and tumor-specific human cd8 t cells is determined by their fine specificity
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