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免疫学杂志2003年第10期封面 购买


cutting edge: diabetes-associated quantitative trait locus, idd4, is responsible for the il-12p40 overexpression defect in nonobese diabetic (nod) mice
cutting edge: effector memory cd8 + t cells in the lung airways retain the potential to mediate recall responses
cutting edge: signaling and cell surface expression of a µh chain in the absence of 5: a paradigm revisited
cutting edge: cd28 controls peripheral homeostasis of cd4 + cd25 + regulatory t cells
cutting edge: t cells from aged mice are resistant to depletion early during virus infection
extrathymic tcr gene rearrangement in human small intestine: identification of new splice forms of recombination activating gene-1 mrna with selective tissue expres..
airway eosinophils accumulate in the mediastinal lymph nodes but lack antigen-presenting potential for naive t cells
electroporation enables plasmid vaccines to elicit cd8 + t cell responses in the absence of cd4 + t cells
ifn- skews monocyte differentiation into toll-like receptor 7-expressing dendritic cells with potent functional activities
in vivo treatment of class ii mhc-deficient mice with anti-tcr antibody restores the generation of circulating cd4 t cells and optimal architecture of thymic medulla
t/nk bipotent progenitors in the thymus retain the potential to generate dendritic cells
death decoy receptor tr6/dcr3 inhibits t cell chemotaxis in vitro and in vivo
kir2dl4 is an il-2-regulated nk cell receptor that exhibits limited expression in humans but triggers strong ifn- production
veto-like activity of mesenchymal stem cells: functional discrimination between cellular responses to alloantigens and recall antigens
essential role for stat5 signaling in cd25 + cd4 + regulatory t cell homeostasis and the maintenance of self-tolerance
il-2-activated cd8 + cd44 high cells express both adaptive and innate immune system receptors and demonstrate specificity for syngeneic tumor cells
neuropeptide y (npy) suppresses experimental autoimmune encephalomyelitis: npy 1 receptor-specific inhibition of autoreactive th1 responses in vivo
diversity of clonal t cell proliferation is mediated by differential expression of cd152 (ctla-4) on the cell surface of activated individual t lymphocytes
human tumor-derived heat shock protein 96 mediates in vitro activation and in vivo expansion of melanoma- and colon carcinoma-specific t cells
cd4 + cd25 + and cd4 + cd25 - t cells act respectively as inducer and effector t suppressor cells in superantigen-induced tolerance
critical role of preconceptional immunization for protective and nonpathological specific immunity in murine neonates
genetic control of tolerance to type ii collagen and development of arthritis in an autologous collagen-induced arthritis model
transduction of multiple effects of sphingosine 1-phosphate (s1p) on t cell functions by the s1p 1 g protein-coupled receptor
opposing signals from pathogen-associated molecular patterns and il-10 are critical for optimal dendritic cell induction of in vivo humoral immunity to streptococcu..
activation of discoidin domain receptor 1 facilitates the maturation of human monocyte-derived dendritic cells through the tnf receptor associated factor 6/tgf- -ac..
dna fragments of the human 60-kda heat shock protein (hsp60) vaccinate against adjuvant arthritis: identification of a regulatory hsp60 peptide
genetic reprogramming of primary human t cells reveals functional plasticity in th cell differentiation
induction of macrophage insulin-like growth factor-i expression by the th2 cytokines il-4 and il-13
cc chemokine ligand 2 and its receptor regulate mucosal production of il-12 and tgf- in high dose oral tolerance
gated importation of prothymocytes by adult mouse thymus is coordinated with their periodic mobilization from bone marrow
cellular events involved in butyric acid-induced t cell apoptosis
exogenous administration of gangliosides inhibits fc ri-mediated mast cell degranulation by decreasing the activity of phospholipase c
morpholino antisense oligonucleotide-mediated gene knockdown during thymocyte development reveals role for runx3 transcription factor in cd4 silencing during develo..
dna-rag protein interactions in the control of selective d gene utilization in the tcr locus
t cell-specific expression of the human tnf- gene involves a functional and highly conserved chromatin signature in intron 3
receptor activator of nf- b ligand stimulates recruitment of shp-1 to the complex containing tnfr-associated factor 6 that regulates osteoclastogenesis
identification of novel il-4/stat6-regulated genes in t lymphocytes
protein kinase a regulatory subunit type ii directly interacts with and suppresses creb transcriptional activity in activated t cells
lipopolysaccharide-induced suppression of airway th2 responses does not require il-12 production by dendritic cells
global gene expression profiles during acute pathogen-induced pulmonary inflammation reveal divergent roles for th1 and th2 responses in tissue repair
flagellin is the major proinflammatory determinant of enteropathogenic salmonella
involvement of leucine residues at positions 107, 112, and 115 in a leucine-rich repeat motif of human toll-like receptor 2 in the recognition of diacylated lipopro..
cd11b + peyers patch dendritic cells secrete il-6 and induce iga secretion from naive b cells
ifn- -independent effects of il-12 during intestinal nematode infection
strong cytosine-guanosine-independent immunostimulation in humans and other primates by synthetic oligodeoxynucleotides with pynttttgt motifs
the role of interleukin-10 in susceptibility of balb/c mice to infection with leishmania mexicana and leishmania amazonensis
cysteine protease b of leishmania mexicana inhibits host th1 responses and protective immunity
impacts of avidity and specificity on the antiviral efficiency of hiv-1-specific ctl
il-12 regulates an endothelial cell-lymphocyte network: effect on metalloproteinase-9 production
eosinophil major basic protein stimulates neutrophil superoxide production by a class i a phosphoinositide 3-kinase and protein kinase c- -dependent pathway
inhibition of cytokine gene transcription by the human recombinant histamine-releasing factor in human t lymphocytes
inflammatory cytokine expression is independent of the c-jun n-terminal kinase/ap-1 signaling cascade in human neutrophils
substance p regulates th1-type colitis in il-10 knockout mice
viral induction of inflammatory cytokines in human epithelial cells follows a p38 mitogen-activated protein kinase-dependent but nf- b-independent pathway
immunomodulatory role of cxcr2 during experimental septic peritonitis
p21-activated kinase 2 in neutrophils can be regulated by phosphorylation at multiple sites and by a variety of protein phosphatases
janus kinase 2 activation by the platelet-activating factor receptor (pafr): roles of tyk2 and pafr c terminus
involvement of dectin-2 in ultraviolet radiation-induced tolerance
activation of mast cells is essential for development of house dust mite dermatophagoides farinae -induced allergic airway inflammation in mice
s sµ and s s switch circles in human nasal mucosa following ex vivo allergen challenge: evidence for direct as well as sequential class switch recombination
cytokines regulate the pattern of rejection and susceptibility to cyclosporine therapy in different mouse recipient strains after cardiac allografting
evolution of cd8 + t cell immunity and viral escape following acute hiv-1 infection
genetic evidence for involvement of classical complement pathway in induction of experimental autoimmune myasthenia gravis
antagonistic effects of tnf- on tgf- signaling through down-regulation of tgf- receptor type ii in human dermal fibroblasts
curcumin (diferuloylmethane) inhibits constitutive and il-6-inducible stat3 phosphorylation in human multiple myeloma cells
the sgp3 locus on mouse chromosome 13 regulates nephritogenic gp70 autoantigen expression and predisposes to autoimmunity
islet allograft rejection in nonobese diabetic mice involves the common -chain and cd28/cd154-dependent and -independent mechanisms
molecular signatures of anti-nuclear antibodies: contributions of specific light chain residues and a novel new zealand black v 1 germline gene
cutting edge: cyclooxygenase-2 activation suppresses th1 polarization in response to helicobacter pylori
specific inhibition of stat5a/b promotes apoptosis of il-2-responsive primary and tumor-derived lymphoid cells
different dynamics of cd4 + and cd8 + t cell responses during and after acute lymphocytic choriomeningitis virus infection
prostaglandin d 2 inhibits airway dendritic cell migration and function in steady state conditions by selective activation of the d prostanoid receptor 1
intratumor cpg-oligodeoxynucleotide injection induces protective antitumor t cell immunity
mediation of enhanced transcription of the il-10 gene in t cells, upon contact with human glioma cells, by fas signaling through a protein kinase a-independent path..
functional effects of tnf- on a human follicular dendritic cell line: persistent nf- b activation and sensitization for fas-mediated apoptosis
regulation of developing b cell survival by rela-containing nf- b complexes
highly biased type 1 immune responses in mice deficient in lfa-1 in listeria monocytogenes infection are caused by elevated il-12 production by granulocytes
expression and function of toll-like receptors in eosinophils: activation by toll-like receptor 7 ligand
burn injury promotes antigen-driven th2-type responses in vivo
th1 cytokines regulate adenosine receptors and their downstream signaling elements in human microvascular endothelial cells
broadly increased sensitivity to cytotoxic t lymphocytes resulting from nef epitope escape mutations
mhc class i gene conversion mutations alter the cd8 t cell repertoire
coordinate regulation of lymphocyte-endothelial interactions by pregnancy-associated hormones
glycolipid antigen drives rapid expansion and sustained cytokine production by nk t cells
immunization with th-ctl fusion peptide and cytosine-phosphate-guanine dna in transgenic hla-a2 mice induces recognition of hiv-infected t cells and clears vaccinia..
dynamics of pathogenic and suppressor t cells in autoimmune diabetes development
the central tolerance response to male antigen in normal mice is deletion and not receptor editing
hsp110-her2/ neu chaperone complex vaccine induces protective immunity against spontaneous mammary tumors in her-2/ neu transgenic mice
the tetraspanin cd81 regulates the expression of cd19 during b cell development in a postendoplasmic reticulum compartment
psychological stress exerts an adjuvant effect on skin dendritic cell functions in vivo
t cells induce extended class ii mhc compartments in dendritic cells in a toll-like receptor-dependent manner
functional segregation of the tcr and antigen-mhc complexes on the surface of ctl
t cell development in mice expressing cd1d directed by a classical mhc class ii promoter
expression of cd1d under the control of a mhc class ia promoter skews the development of nkt cells, but not cd8 + t cells
t cell-specific disruption of arylhydrocarbon receptor nuclear translocator ( arnt ) gene causes resistance to 2,3,7,8-tetrachlorodibenzo- p -dioxin-induced thymic ..
enhanced effector and memory ctl responses generated by incorporation of receptor activator of nf- b (rank)/rank ligand costimulatory molecules into dendritic cell ..
clonal expansion of double-positive intraepithelial lymphocytes by mhc class i-related chain a expressed in mouse small intestinal epithelium
clustering of th cell epitopes on exposed regions of hiv envelope despite defects in antibody activity
lysosomal localization of murine cd1d mediated by ap-3 is necessary for nk t cell development
blockade of b7-h1 suppresses the development of chronic intestinal inflammation
exposure of human primary colon carcinoma cells to anti-fas interactions influences the emergence of pre-existing fas-resistant metastatic subpopulations
ex vivo analysis of thymic cd4 t cells in nonobese diabetic mice with tetramers generated from i-a g7 /class ii-associated invariant chain peptide precursors
ifn- -induced mhc class ii expression: transactivation of class ii transactivator promoter iv by ifn regulatory factor-1 is regulated by protein kinase c-
the rac-activating toxin cytotoxic necrotizing factor 1 oversees nk cell-mediated activity by regulating the actin/microtubule interplay
phosphatidylcholine-specific phospholipase c activity is necessary for the activation of stat6
nf- b regulates bcl3 transcription in t lymphocytes through an intronic enhancer
transcriptional control of murine cd94 gene: differential usage of dual promoters by lymphoid cell types
dual phosphorylation of phosphoinositide 3-kinase adaptor grb2-associated binder 2 is responsible for superoxide formation synergistically stimulated by fc and form..
receptor glycosylation regulates ly-49 binding to mhc class i
hemozoin increases ifn- -inducible macrophage nitric oxide generation through extracellular signal-regulated kinase- and nf- b-dependent pathways
deficient anti-listerial immunity in the absence of perforin can be restored by increasing memory cd8 + t cell numbers
evidence for naturally acquired t cell-mediated mucosal immunity to neisseria meningitidis 1,
myosin autoimmunity is not essential for cardiac inflammation in acute chagas disease
functional characterization of class ia- and non-class ia-restricted chlamydia -reactive cd8 + t cell responses in humans
mucosally delivered e1-deleted adenoviral vaccine carriers induce transgene product-specific antibody responses in neonatal mice
a dominant role of toll-like receptor 4 in the signaling of apoptosis in bacteria-faced macrophages
toll/il-1 receptor domain-containing adaptor inducing ifn- (trif) associates with tnf receptor-associated factor 6 and tank-binding kinase 1, and activates two dist..
costimulatory molecule immune enhancement in a plasmid vaccine model is regulated in part through the ig constant-like domain of cd80/86
toll-like receptor ligands modulate dendritic cells to augment cytomegalovirus- and hiv-1-specific t cell responses
compromised host defense on pseudomonas aeruginosa biofilms: characterization of neutrophil and biofilm interactions
up-regulation of matrix metalloproteinase-9 in t lymphocytes of mammary tumor bearers: role of vascular endothelial growth factor
selective depletion of nonspecific t cells during the early stage of immune responses to infection
th1-biased tertiary lymphoid tissue supported by cxc chemokine ligand 13-producing stromal network in chronic lesions of autoimmune gastritis
regulation of eotaxin gene expression by tnf- and il-4 through mrna stabilization: involvement of the rna-binding protein hur
blockade of airway inflammation and hyperresponsiveness by hiv-tat-dominant negative ras
mast cells exert effects outside the central nervous system to influence experimental allergic encephalomyelitis disease course
tnf- induces phosphorylation of p47 phox in human neutrophils: partial phosphorylation of p47 phox is a common event of priming of human neutrophils by tnf- and gra..
activation of group iv cytosolic phospholipase a 2 in human eosinophils by phosphoinositide 3-kinase through a mitogen-activated protein kinase-independent pathway
il-8/cxcl8 and growth-related oncogene /cxcl1 induce chondrocyte hypertrophic differentiation
defective phagocytosis and clearance of pseudomonas aeruginosa in the lung following bone marrow transplantation
the hemopoietic rho/rac guanine nucleotide exchange factor vav1 regulates n -formyl-methionyl-leucyl-phenylalanine-activated neutrophil functions
hla-drb10402 (dw10) transgene protects collagen- induced arthritis-susceptible h2a q and drb10401 (dw4) transgenic mice from arthritis
repeated -galactosylceramide administration results in expansion of nk t cells and alleviates inflammatory dermatitis in mrl- lpr/lpr mice
il-7 stimulates t cell renewal without increasing viral replication in simian immunodeficiency virus-infected macaques
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