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免疫学杂志2003年第08期封面 购买


cutting edge: in vivo induction of integrated hiv-1 expression by mycobacteria is critically dependent on toll-like receptor 2
cutting edge: t lymphocyte activation by repeated immunological synapse formation and intermittent signaling
baculovirus induces an innate immune response and confers protection from lethal influenza virus infection in mice
differential expression of smad7 transcripts identifies the cd4 + cd45rc high regulatory t cells that mediate type v collagen-induced tolerance to lung allografts
macrophages of the splenic marginal zone are essential for trapping of blood-borne particulate antigen but dispensable for induction of specific t cell responses
the immune response modifier and toll-like receptor 7 agonist s-27609 selectively induces il-12 and tnf- production in cd11c + cd11b + cd8 - dendritic cells
il-18 binding protein protects against contact hypersensitivity
constitutive caspase activation and impaired death-inducing signaling complex formation in cd95-resistant, long-term activated, antigen-specific t cells
fas ligand on tumor cells mediates inactivation of neutrophils
antibody repertoire and gene expression profile: implications for different developmental and functional traits of splenic and peritoneal b-1 lymphocytes
hemopoietic function after use of il-1 with chemotherapy or irradiation
early defect prethymic in bone marrow t cell progenitors in athymic nu/nu mice
scurfin (foxp3) controls t-dependent immune responses in vivo through regulation of cd4 + t cell effector function
theileria parva -transformed t cells show enhanced resistance to fas/fas ligand-induced apoptosis
l -arginine consumption by macrophages modulates the expression of cd3 chain in t lymphocytes
enhanced priming of multispecific, murine cd8 + t cell responses by dna vaccines expressing stress protein-binding polytope peptides
regulation of polyclonal t cell responses by an mhc anchor-substituted variant of myelin oligodendrocyte glycoprotein 35-55
a giant gtpase, very large inducible gtpase-1, is inducible by ifns
cd4 + nkt cells, but not conventional cd4 + t cells, are required to generate efferent cd8 + t regulatory cells following antigen inoculation in an immune-privilege..
blockade of programmed death-1 engagement accelerates graft-versus-host disease lethality by an ifn- -dependent mechanism
chronic exposure to low levels of antigen in the periphery causes reversible functional impairment correlating with changes in cd5 levels in monoclonal cd8 t cells
constitutively active protein kinase b enhances lck and erk activities and influences thymocyte selection and activation
the onecut transcription factor hepatocyte nuclear factor-6 controls b lymphopoiesis in fetal liver
mutation of a dibasic amino acid motif within the c terminus of the p2x 7 nucleotide receptor results in trafficking defects and impaired function
the porcine ig gene: unique chimeric splicing of the first constant region domain in its heavy chain transcripts 1,
the lyn tyrosine kinase negatively regulates neutrophil integrin signaling
b cell receptor-mediated syk-independent activation of phosphatidylinositol 3-kinase, ras, and mitogen-activated protein kinase pathways
identification and characterization of a novel regulatory factor: iga-inducing protein
complexes of hla-g protein on the cell surface are important for leukocyte ig-like receptor-1 function
positive modulation of il-12 signaling by sphingosine kinase 2 associating with the il-12 receptor 1 cytoplasmic region
slp-76 coordinates nck-dependent wiskott-aldrich syndrome protein recruitment with vav-1/cdc42-dependent wiskott-aldrich syndrome protein activation at the t cell-a..
analysis of hla-e peptide-binding specificity and contact residues in bound peptide required for recognition by cd94/nkg2
protein expression and peptide binding suggest unique and interacting functional roles for hla-e, f, and g in maternal-placental immune recognition
functional analysis of the tcr binding domain of toxic shock syndrome toxin-1 predicts further diversity in mhc class ii/superantigen/tcr ternary complexes
repetitive elements in mammalian telomeres suppress bacterial dna-induced immune activation
inhibition of ifn- -inducible protein-10 abrogates colitis in il-10 -/- mice
promiscuous ctl recognition of viral epitopes on multiple human leukocyte antigens: biological validation of the proposed hla a24 supertype
alternate class i mhc antigen processing is inhibited by toll-like receptor signaling pathogen-associated molecular patterns: mycobacterium tuberculosis 19-kda lipo..
clearance of pneumocystis carinii in mice is dependent on b cells but not on p. carinii -specific antibody
porcine pulmonary collectins show distinct interactions with influenza a viruses: role of the n -linked oligosaccharides in the carbohydrate recognition domain
heat-killed brucella abortus induces tnf and il-12p40 by distinct myd88-dependent pathways: tnf, unlike il-12p40 secretion, is toll-like receptor 2 dependent
leptospira interrogans activation of human peripheral blood mononuclear cells: preferential expansion of tcr + t cells vs tcr + t cells
inhibition of a p38/stress-activated protein kinase-2-dependent phosphatase restores function of il-1 receptor-associated kinase-1 and reverses toll-like receptor 2..
glycosylinositolphosphate soluble variant surface glycoprotein inhibits ifn- -induced nitric oxide production via reduction in stat1 phosphorylation in african tryp..
injury primes the innate immune system for enhanced toll-like receptor reactivity
nf- b is required within the innate immune system to inhibit microflora-induced colitis and expression of il-12 p40
human mast cell -tryptase is a gelatinase
pellino3, a novel member of the pellino protein family, promotes activation of c-jun and elk-1 and may act as a scaffolding protein
murine macrophages produce secretory leukocyte protease inhibitor during clearance of apoptotic cells: implications for resolution of the inflammatory response
the proteasome as a lipopolysaccharide-binding protein in macrophages: differential effects of proteasome inhibition on lipopolysaccharide-induced signaling events
trail induces apoptosis and inflammatory gene expression in human endothelial cells
proangiogenic function of cd40 ligand-cd40 interactions 1,
role of regulator of g protein signaling 16 in inflammation- induced t lymphocyte migration and activation
mucosal t cells expressing high levels of il-7 receptor are potential targets for treatment of chronic colitis
pivotal role of stat4 and stat6 in the pathogenesis of the lupus-like disease in the new zealand mixed 2328 mice
systemic rather than local heme oxygenase-1 overexpression improves cardiac allograft outcomes in a new transgenic mouse
complement activation determines the therapeutic activity of rituximab in vivo
her-2 dna and protein vaccines containing potent th cell epitopes induce distinct protective and therapeutic antitumor responses in her-2 transgenic mice
inhibitory signal override increases susceptibility to mercury-induced autoimmunity
enhanced immunogenicity and protective efficacy against mycobacterium tuberculosis of bacille calmette-guérin vaccine using mucosal administration and boosting wit..
cutting edge: invariant v 14 nkt cells are required for allergen-induced airway inflammation and hyperreactivity in an experimental asthma model
cutting edge: the b cell chemokine cxc chemokine ligand 13/b lymphocyte chemoattractant is expressed in the high endothelial venules of lymph nodes and peyers patch..
cutting edge: sr-psox/cxc chemokine ligand 16 mediates bacterial phagocytosis by apcs through its chemokine domain
cutting edge: induced indoleamine 2,3 dioxygenase expression in dendritic cell subsets suppresses t cell clonal expansion
germinal centers regulate human th2 development
lymphocyte accumulation in the spleen of retinoic acid receptor-related orphan receptor -deficient mice
mechanisms of ganglioside inhibition of apc function
plasma cell survival is mediated by synergistic effects of cytokines and adhesion-dependent signals
differential localization and function of adp-ribosylation factor-6 in anergic human t cells: a potential marker for their identification
functional dissection of lupus susceptibility loci on the new zealand black mouse chromosome 1: evidence for independent genetic loci affecting t and b cell activat..
selective inhibition of t cell activation via cd147 through novel modulation of lipid rafts
blastocyst mhc, a putative murine homologue of hla-g, protects tap-deficient tumor cells from natural killer cell-mediated rejection in vivo
ccr3 expression induced by il-2 and il-4 functioning as a death receptor for b cells
synoviocyte-mediated expansion of inflammatory t cells in rheumatoid synovitis is dependent on cd47-thrombospondin 1 interaction
identifying mhc class i epitopes by predicting the tap transport efficiency of epitope precursors
rna interference shows critical requirement for nf- b p50 in the production of il-12 by human dendritic cells
incomplete activation of cd4 t cells by antigen-presenting transitional immature b cells: implications for peripheral b and t cell responsiveness
kir2dl4 (cd158d) genotype influences expression and function in nk cells
nkt cells from normal and tumor-bearing human livers are phenotypically and functionally distinct from murine nkt cells
induced dendritic cell differentiation of chronic myeloid leukemia blasts is associated with down-regulation of bcr-abl
either of the cd45rb and cd45ro isoforms are effective in restoring t cell, but not b cell, development and function in cd45-null mice
break of neonatal th1 tolerance and exacerbation of experimental allergic encephalomyelitis by interference with b7 costimulation
il-18 stimulates the proliferation and ifn- release of cd4 + t cells in the chicken: conservation of a th1-like system in a nonmammalian species
t cell-intrinsic requirement for nf- b induction in postdifferentiation ifn- production and clonal expansion in a th1 response
the human fascin gene promoter is highly active in mature dendritic cells due to a stage-specific enhancer
inhibitory coreceptors activated by antigens but not by anti-ig heavy chain antibodies install requirement of costimulation through cd40 for survival and proliferat..
3 domain mutants of peptide/mhc class i multimers allow the selective isolation of high avidity tumor-reactive cd8 t cells
reduced dosage of brutons tyrosine kinase uncouples b cell hyperresponsiveness from autoimmunity in lyn -/- mice
apoptosis by neglect of cd4 + th cells in granulomas: a novel effector mechanism involved in the control of egg-induced immunopathology in murine schistosomiasis
pathogen-associated molecular patterns sensitize macrophages to fas ligand-induced apoptosis and il-1 release
a catalytically inactive form of protein kinase c-associated kinase/receptor interacting protein 4, a protein kinase c -associated kinase that mediates nf- b activa..
studies of structure-activity relations of complement inhibitor compstatin
new programming of il-4 receptor signal transduction in activated t cells: stat6 induction and th2 differentiation mediated by il-4r lacking cytoplasmic tyrosines
the cd43 coreceptor molecule recruits the -chain as part of its signaling pathway
potential role of nkg2d/mhc class i-related chain a interaction in intrathymic maturation of single-positive cd8 t cells
2 -microglobulin-free hla class i heavy chain epitope mimicry by monoclonal antibody hc-10-specific peptide
a novel -66t/c polymorphism in fc ri -chain promoter affecting the transcription activity: possible relationship to allergic diseases
recombinant tcr ligand induces early tcr signaling and a unique pattern of downstream activation
human immature monocyte-derived dendritic cells express the g protein-coupled receptor gpr105 (kiaa0001, p2y 14 ) and increase intracellular calcium in response to ..
brugia malayi microfilariae induce cell death in human dendritic cells, inhibit their ability to make il-12 and il-10, and reduce their capacity to activate cd4 + t..
an anti-inflammatory role for v 14 nk t cells in mycobacterium bovis bacillus calmette-guérin-infected mice
t cell costimulatory molecule function determines susceptibility to infection with pneumocystis carinii in mice
the fourth surface-exposed region of the outer membrane protein p5-homologous adhesin of nontypable haemophilus influenzae is an immunodominant but nonprotective de..
presentation and binding affinity of equine infectious anemia virus ctl envelope and matrix protein epitopes by an expressed equine classical mhc class i molecule
nramp1 functionality increases inducible nitric oxide synthase transcription via stimulation of ifn regulatory factor 1 expression
dna vaccines, combining form of antigen and method of delivery to raise a spectrum of ifn- and il-4-producing cd4 + and cd8 + t cells
protection against ctl escape and clinical disease in a murine model of virus persistence
lipomannans, but not lipoarabinomannans, purified from mycobacterium chelonae and mycobacterium kansasii induce tnf- and il-8 secretion by a cd14-toll-like receptor..
protracted protection to plasmodium berghei malaria is linked to functionally and phenotypically heterogeneous liver memory cd8 + t cells
helicobacter pylori infection interferes with epithelial stat6-mediated interleukin-4 signal transduction independent of caga, cage, or vaca
mycobacterium tuberculosis exerts gene-selective inhibition of transcriptional responses to ifn- without inhibiting stat1 function
expression and function of formyl peptide receptors on human fibroblast cells
plasminogen activator inhibitor-1 supports il-8-mediated neutrophil transendothelial migration by inhibition of the constitutive shedding of endothelial il-8/hepara..
inflammatory chemoreceptor cross-talk suppresses leukotriene b 4 receptor 1-mediated neutrophil calcium mobilization and chemotaxis after trauma
functional expression of neurokinin 1 receptors on mast cells induced by il-4 and stem cell factor
airway igg counteracts specific and bystander allergen-triggered pulmonary inflammation by a mechanism dependent on fc r and ifn-
synergism between platelet-activating factor-like phospholipids and peroxisome proliferator-activated receptor agonists generated during low density lipoprotein oxi..
intracellular domain of brain endothelial intercellular adhesion molecule-1 is essential for t lymphocyte-mediated signaling and migration
prevention of collagen-induced arthritis in mice transgenic for the complement inhibitor complement receptor 1-related gene/protein y
a plant-based allergy vaccine suppresses experimental asthma via an ifn- and cd4 + cd45rb low t cell-dependent mechanism
a novel therapeutic approach targeting articular inflammation using the filarial nematode-derived phosphorylcholine-containing glycoprotein es-6
differentiation of cd8 + t cells from tumor-invaded and tumor-free lymph nodes of melanoma patients: role of common -chain cytokines
immunoregulatory role of cd1d in the hydrocarbon oil-induced model of lupus nephritis
reconstitution of cd8 + t cells by retroviral transfer of the tcr -chain genes isolated from a clonally expanded p815-infiltrating lymphocyte
her-2/neu-specific monoclonal antibodies collaborate with her-2/neu-targeted granulocyte macrophage colony-stimulating factor secreting whole cell vaccination to au..
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