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免疫学杂志2003年第02期封面 购买


cutting edge: ifn consensus sequence binding protein/ifn regulatory factor 8 drives the development of type i ifn-producing plasmacytoid dendritic cells
cutting edge: profile of chemokine receptor expression on human plasma cells accounts for their efficient recruitment to target tissues
transgenic expression of rasgrp1 induces the maturation of double-negative thymocytes and enhances the production of cd8 single-positive thymocytes
deregulated mhc class ii transactivator expression leads to a strong th2 bias in cd4 + t lymphocytes
comparative effects of human ig and ig in inducing autoreactive antibodies against b cells in mice
sustained depolarization and adp-ribose activate a common ionic current in rat peritoneal macrophages
ifn- released by mycobacterium tuberculosis -infected human dendritic cells induces the expression of cxcl10: selective recruitment of nk and activated t cells
tumor eradication by hepatitis b virus x antigen-specific cd8 + t cells in xenografted nude mice
cross-presentation of hla class i epitopes from exogenous ny-eso-1 polypeptides by nonprofessional apcs
the contribution of nkt cells, nk cells, and other -chain-dependent non-t non-b cells to il-12-mediated rejection of tumors
broadening of epitope recognition during immune rejection of erbb-2-positive tumor prevents growth of erbb-2-negative tumor
transfer of tcr genes into mature t cells is accompanied by the maintenance of parental t cell avidity
differential antigen sensitivity and costimulatory requirements in human th1 and th2 antigen-specific cd4 + cells with similar tcr avidity
tcr reserve: a novel principle of cd4 t cell activation by weak ligands
preferential escape of subdominant cd8 + t cells during negative selection results in an altered antiviral t cell hierarchy
role for il-10 in suppression mediated by peptide-induced regulatory t cells in vivo
critical role of mhc class i-related chain a and b expression on ifn- -stimulated dendritic cells in nk cell activation: impairment in chronic hepatitis c virus inf..
blockade of programmed death-1 ligands on dendritic cells enhances t cell activation and cytokine production
enhanced differentiation of splenic plasma cells but diminished long-lived high-affinity bone marrow plasma cells in aged mice
in vivo blockade of macrophage migration inhibitory factor ameliorates acute experimental autoimmune encephalomyelitis by impairing the homing of encephalitogenic t..
ly6c induces clustering of lfa-1 (cd11a/cd18) and is involved in subtype-specific adhesion of cd8 t cells
induction of antigen-specific ctl by recombinant hiv trans -activating fusion protein-pulsed human monocyte-derived dendritic cells
entry into the thymic microenvironment triggers notch activation in the earliest migrant t cell progenitors
inhibitory feedback loop between tolerogenic dendritic cells and regulatory t cells in transplant tolerance
tgf- regulates airway responses via t cells
tnf- plus ifn- induce connexin43 expression and formation of gap junctions between human monocytes/macrophages that enhance physiological responses
mhc class ii-peptide complexes and apc lipid rafts accumulate at the immunological synapse
rules for gene usage inferred from a comparison of large-scale gene expression profiles of t and b lymphocyte development
block in development at the pre-b-ii to immature b cell stage in mice without ig and ig light chain
mimicry of native peptide antigens by the corresponding retro-inverso analogs is dependent on their intrinsic structure and interaction propensities
natural substrates and inhibitors of mannan-binding lectin-associated serine protease-1 and -2: a study on recombinant catalytic fragments
suppressor of cytokine signaling 1 inhibits il-10-mediated immune responses
the shift of th1 to th2 immunodominance associated with the chronicity of mycobacterium bovis bacille calmette-guérin infection does not affect the memory response
lipopolysaccharide (lps)-binding protein mediates lps detoxification by chylomicrons
human intestinal epithelial cells are broadly unresponsive to toll-like receptor 2-dependent bacterial ligands: implications for host-microbial interactions in the ..
a simian replication-defective adenoviral recombinant vaccine to hiv-1 gag
nonspecific recruitment of memory cd8 + t cells to the lung airways during respiratory virus infections
impaired clearance of herpes simplex virus type 1 from mice lacking cd1d or nkt cells expressing the semivariant v 14-j 281 tcr
a soluble chemokine-binding protein from vaccinia virus reduces virus virulence and the inflammatory response to infection
a specific role for b cells in the generation of cd8 t cell memory by recombinant listeria monocytogenes
ccl28 has dual roles in mucosal immunity as a chemokine with broad-spectrum antimicrobial activity
differential expression of the murine mannose-binding lectins a and c in lymphoid and nonlymphoid organs and tissues
the long pentraxin ptx3 is synthesized in iga glomerulonephritis and activates mesangial cells
mhc class ii-associated invariant chain isoforms regulate pulmonary immune responses
cytochrome p4502d6 193-212 : a new immunodominant epitope and target of virus/self cross-reactivity in liver kidney microsomal autoantibody type 1-positive liver di..
cd4 + th2 cell recognition of hla-dr-restricted epitopes derived from camel: a tumor antigen translated in an alternative open reading frame
induction of antigen-specific ctl responses using antigens conjugated to short peptide vectors
bordetella pertussis infection in 2-month-old infants promotes type 1 t cell responses
cd28/b7 regulation of anti-cd3-mediated immunosuppression in vivo
lack of a functional alternative complement pathway ameliorates ischemic acute renal failure in mice
a novel anti-inflammatory role for simvastatin in inflammatory arthritis
the in vitro and in vivo effects of anti-galactose antibodies on endothelial cell activation and xenograft rejection
increased bone mass is a part of the generalized lymphoproliferative disorder phenotype in the mouse 1,
oral feeding with ethinyl estradiol suppresses and treats experimental autoimmune encephalomyelitis in sjl mice and inhibits the recruitment of inflammatory cells i..
peptide nucleic acid antisense prolongs skin allograft survival by means of blockade of cxcr3 expression directing t cells into graft
induction of apoptosis by hiv-1-infected monocytic cells
normal tissue depresses while tumor tissue enhances human t cell responses in vivo to a novel self/tumor melanoma antigen, oa
transcutaneous immunization with cholera toxin b subunit adjuvant suppresses ige antibody responses via selective induction of th1 immune responses
cutting edge: perforin down-regulates cd4 and cd8 t cell-mediated immune responses to a transplanted organ
cutting edge: immediate rantes secretion by resting memory cd8 t cells following antigenic stimulation
cutting edge: the g-u mismatch glycosylase methyl-cpg binding domain 4 is dispensable for somatic hypermutation and class switch recombination
cutting edge: distinct toll-like receptor 2 activators selectively induce different classes of mediator production from human mast cells 1,
cutting edge: both activating and inhibitory fc receptors expressed on mast cells regulate experimental allergic encephalomyelitis disease severity
cutting edge: carbohydrate profiling identifies new pathogens that interact with dendritic cell-specific icam-3-grabbing nonintegrin on dendritic cells
targeting apoptotic tumor cells to fc r provides efficient and versatile vaccination against tumors by dendritic cells
th1 and th2 pancreatic inflammation differentially affects homing of islet-reactive cd4 cells in nonobese diabetic mice
a unique population of extrathymically derived tcr + cd4 - cd8 - t cells with regulatory functions dominates the mouse female genital tract
cd40 ligand in pathogenesis of autoimmune ovarian disease of day 3-thymectomized mice: implication for cd40 ligand antibody therapy
cd4 + cd25 - t cells in aged mice are hyporesponsive and exhibit suppressive activity
allergen-independent maternal transmission of asthma susceptibility
epitope spreading is not required for relapses in experimental autoimmune encephalomyelitis
lack of the transcriptional coactivator obf-1 prevents the development of systemic lupus erythematosus-like phenotypes in aiolos mutant mice
b cell developmental requirement for the g i2 gene
hiv-1 nef induces the release of inflammatory factors from human monocyte/macrophages: involvement of nef endocytotic signals and nf- b activation
pertussis toxin enhances th1 responses by stimulation of dendritic cells
preferential survival of cd8 t and nk cells expressing high levels of cd94
the leishmania mexicana cysteine protease, cpb2.8, induces potent th2 responses
protective mucosal immunity in aging is associated with functional cd4 + t cells in nasopharyngeal-associated lymphoreticular tissue
expression of ifn- upon triggering of activating ly49d nk receptors in vitro and in vivo: costimulation with il-12 or il-18 overrides inhibitory receptors
nf- b hyperactivation has differential effects on the apc function of nonobese diabetic mouse macrophages
antibody repertoire development in fetal and neonatal piglets. vi. b cell lymphogenesis occurs at multiple sites with differences in the frequency of in-frame rearr..
the th2 cell cytokines il-4 and il-13 regulate found in inflammatory zone 1/resistin-like molecule gene expression by a stat6 and ccaat/enhancer-binding protein-dep..
cooperation of tnf family members cd40 ligand, receptor activator of nf- b ligand, and tnf- in the activation of dendritic cells and the expansion of viral specific..
suppressive dna vaccination in myelin oligodendrocyte glycoprotein peptide-induced experimental autoimmune encephalomyelitis involves a t1-biased immune response
tnf-related apoptosis-inducing ligand mediates tumoricidal activity of human monocytes stimulated by newcastle disease virus
antigen density presented by dendritic cells in vivo differentially affects the number and avidity of primary, memory, and recall cd8 + t cells
naturally occurring human igm antibody that binds b7-dc and potentiates t cell stimulation by dendritic cells
temperature effect on ige binding to cd23 versus fc ri
role of double-negative regulatory t cells in long-term cardiac xenograft survival
immunoglobulin superantigen protein l induces il-4 and il-13 secretion from human fc ri + cells through interaction with the light chains of ige
h2-m3-restricted memory t cells: persistence and activation without expansion
stat signals release activated naive th cells from an anergic checkpoint
characterization of thymic progenitors in adult mouse bone marrow
human activation-induced cytidine deaminase is induced by il-4 and negatively regulated by cd45: implication of cd45 as a janus kinase phosphatase in antibody diver..
locus-specific constitutive and cytokine-induced hla class i gene expression
restoration of ig secretion: mutation of germline-encoded residues in t15l chains leads to secretion of free light chains and assembled antibody complexes bearing s..
structure function differences in nonpeptide ccr1 antagonists for human and mouse ccr
crystal structure of a hydrophobic immunodominant antigenic site on hepatitis c virus core protein complexed to monoclonal antibody 19d9d6
associations of mhc ancestral haplotypes with resistance/susceptibility to aids disease development
ctla-4 in filarial infections: implications for a role in diminished t cell reactivity
constrained intracellular survival of mycobacterium tuberculosis in human dendritic cells
the induction and kinetics of antigen-specific cd8 t cells are defined by the stage specificity and compartmentalization of the antigen in murine toxoplasmosis
cd4 + t cells mediate abscess formation in intra-abdominal sepsis by an il-17-dependent mechanism
the mitochondrial network of human neutrophils: role in chemotaxis, phagocytosis, respiratory burst activation, and commitment to apoptosis
mouse swam1 and swam2 are antibacterial proteins composed of a single whey acidic protein motif
prevention of spontaneous breast carcinoma by prophylactic vaccination with dendritic/tumor fusion cells
cd8 + t cells accumulate in the lungs of mycobacterium tuberculosis -infected k b-/- d b-/- mice, but provide minimal protection
nf- b1 is required for optimal cd4 + th1 cell development and resistance to leishmania major
tnf plays an essential role in tumor regression after adoptive transfer of perforin/ifn- double knockout effector t cells
regression of a mammary adenocarcinoma in stat6 -/- mice is dependent on the presence of stat6-reactive t cells
memory inflation: continuous accumulation of antiviral cd8 + t cells over time
modulation of hla-a0201-restricted t cell responses by natural polymorphism in the ie1 315-324 epitope of human cytomegalovirus
il-13 is sufficient for respiratory syncytial virus g glycoprotein-induced eosinophilia after respiratory syncytial virus challenge
persistence and turnover of antigen-specific cd4 t cells during chronic tuberculosis infection in the mouse
role of cd4 t cell help and costimulation in cd8 t cell responses during listeria monocytogenes infection
expression of the long form of human flip by retroviral gene transfer of hemopoietic stem cells exacerbates experimental autoimmune encephalomyelitis
suppression of nf- b activation and proinflammatory cytokine expression by shiga toxin-producing escherichia coli
dual roles of il-4 in lung injury and fibrosis
akt as a mediator of secretory phospholipase a 2 receptor-involved inducible nitric oxide synthase expression
mechanisms of inhibition of collagen-induced arthritis by murine il-18 binding protein
il-17, produced by lymphocytes and neutrophils, is necessary for lipopolysaccharide-induced airway neutrophilia: il-15 as a possible trigger
poly(adp-ribose) polymerase-1 regulates activation of activator protein-1 in murine fibroblasts
lipopolysaccharide down-regulates the leukotriene c 4 synthase gene in the monocyte-like cell line, thp-1
parenchymal, but not leukocyte, tnf receptor 2 mediates t cell-dependent hepatitis in mice
absence of ccr8 does not impair the response to ovalbumin-induced allergic airway disease
synoviocyte-derived cxcl12 is displayed on endothelium and induces angiogenesis in rheumatoid arthritis
induction of experimental autoimmune encephalomyelitis in il-12 receptor- 2-deficient mice: il-12 responsiveness is not required in the pathogenesis of inflammatory..
survival and tumor localization of adoptively transferred melan-a-specific t cells in melanoma patients
induction of pemphigus phenotype by a mouse monoclonal antibody against the amino-terminal adhesive interface of desmoglein 3
lf 15-0195 inhibits the development of rat central nervous system autoimmunity by inducing long-lasting tolerance in autoreactive cd4 t cells
peptide fine specificity of anti-glycoprotein 100 ctl is preserved following transfer of engineered tcr genes into primary human t lymphocytes
absence of il-4, and not suppression of the th2 response, prevents development of experimental autoimmune graves disease
essential roles of perforin in antigen-specific cytotoxicity mediated by human cd4 + t lymphocytes: analysis using the combination of hereditary perforin-deficient ..
microsatellite instability and suppressed dna repair enzyme expression in rheumatoid arthritis
perforin-dependent brain-infiltrating cytotoxic cd8 + t lymphocytes mediate experimental cerebral malaria pathogenesis
t cell reactivity to mhc class ii-bound self peptides in systemic lupus erythematosus-prone mrl/ lpr mice
in vivo efficacy of anti-glycoprotein 41, but not anti-glycoprotein 120, immunotoxins in a mouse model of hiv infection
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