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核酸研究医学期刊2004年第03期封面 购买


the diverse superfamily of lysine acetyltransferases and their roles in leukemia and other diseases
biochemical characterization of the mitochondrial trnaser(ucn) t7511c mutation associated with nonsyndromic deafness
site-resolved stabilization of a dna triple helix by magnesium ions
identification of a direct dlx homeodomain target in the developing mouse forebrain and retina by optimization of chromatin immunoprecipitation
a library of sirna duplexes targeting the phosphoinositide 3-kinase pathway: determinants of gene silencing for use in cell-based screens
inhibitors of protein synthesis identified by a high throughput multiplexed translation screen
kinetic and thermodynamic characterization of the rna-cleaving 8-17 deoxyribozyme
pre-steady-state kinetics shows differences in processing of various dna lesions by escherichia coli formamidopyrimidine-dna glycosylase
guidelines for the selection of highly effective sirna sequences for mammalian and chick rna interference
statistical analysis of over-represented words in human promoter sequences
the genome sequence of bacillus cereus atcc 10987 reveals metabolic adaptations and a large plasmid related to bacillus anthracis pxo1
the effect of manganese(ii) on dna structure: electronic and vibrational circular dichroism studies
phosphatidyl inositol 3-kinase-like serine/threonine protein kinases (pikks) are required for dna damage-induced phosphorylation of the 32 kda subunit of replicatio..
a mutation in polynucleotide phosphorylase from escherichia coli impairing rna binding and degradosome stability
mycobacterium tuberculosis rv2118c codes for a single-component homotetrameric m1a58 trna methyltransferase
rbd-1, a nucleolar rna-binding protein, is essential for caenorhabditis elegans early development through 18s ribosomal rna processing
the importance of intrinsic disorder for protein phosphorylation
biased distribution of dna uptake sequences towards genome maintenance genes
protein interaction mapping on a functional shotgun sequence of rickettsia sibirica
physical and functional interaction of the archaeal single-stranded dna-binding protein ssb with rna polymerase
interactions among cii protein, rna polymerase and the pre promoter: contacts between rna polymerase and the
atypical archaeal trna pyrrolysine transcript behaves towards ef-tu as a typical elongator trna
a thymine tetrad in d(tggggt) quadruplexes stabilized with tl+/na+ ions
assembly of the replication initiation complex on sv40 origin dna
the inhibition of the human cholesterol 7-hydroxylase gene (cyp7a1) promoter by fibrates in cultured cells is mediated via the liver x receptor and peroxisome prol..
translesion synthesis of acetylaminofluorene-dg adducts by dna polymerase is stimulated by yeast rev1 protein
analysis and recognition of 5' utr intron splice sites in human pre-mrna
psoralen interstrand cross-link repair is specifically altered by an adjacent triple-stranded structure
enhanced gene silencing of hiv-1 specific sirna using microrna designed hairpins
overexpression of phage-type rna polymerase rpotp in tobacco demonstrates its role in chloroplast transcription by recognizing a distinct promoter type
relevance of up elements for three strong bacillus subtilis phage 29 promoters
identification of nh...n hydrogen bonds by magic angle spinning solid state nmr in a double-stranded rna associated with myotonic dystrophy
gene repeat expansion and contraction by spontaneous intrachromosomal homologous recombination in mammalian cells
a novel strategy to engineer dna polymerases for enhanced processivity and improved performance in vitro
a gene-specific dna sequencing chip for exploring molecular evolutionary change
delineation of the mechanisms of aberrant splicing caused by two unusual intronic mutations in the rsk2 gene involved in coffin
length-dependent structure formation in friedreich ataxia (gaa)n?(ttc)n repeats at neutral ph
etr-3 and celf4 protein domains required for rna binding and splicing activity in vivo
mer1p is a modular splicing factor whose function depends on the conserved u2 snrnp protein snu17p
determination of detection and quantification limits for snp allele frequency estimation in dna pools using real time pcr
nuclear localization signal and cell synchrony enhance gene targeting efficiency in primary fetal fibroblasts
sequence saturation mutagenesis (sesam): a novel method for directed evolution
genomic shotgun array: a procedure linking large-scale dna sequencing with regional transcript mapping
semiconductor nanocrystal probes for human metaphase chromosomes
reliability of gene expression ratios for cdna microarrays in multiconditional experiments with a reference design
doxycyline regulation in a single retroviral vector by an autoregulatory loop facilitates controlled gene expression in liver cells
large-scale determination of the methylation status of retrotransposons in different tissues using a methylation tags approach
strong positional preference in the interaction of lna oligonucleotides with dna polymerase and proofreading exonuclease activities: implications for genotyping ass..
surfection: a new platform for transfected cell arrays
lsimpute: accurate estimation of missing values in microarray data with least squares methods
unlocking hidden genomic sequence
shuffled antibody libraries created by in vivo homologous recombination and yeast surface display
simple cdna normalization using kamchatka crab duplex-specific nuclease
a simple method for estimating global dna methylation using bisulfite pcr of repetitive dna elements
generating in vitro transcripts with homogenous 3' ends using trans-acting antigenomic delta ribozyme
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